Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 66

Sort by

Sort Order Select

Journal Articles

4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model

Abigail Ballard-Kordeliski, Robert H. Lee, Ellen C. O’Shaughnessy, Paul Y. Kim, Summer R. Jones, Rafal Pawlinski, Matthew J. Flick, David S. Paul, Nigel Mackman, David A. Adalsteinsson, Wolfgang Bergmeier

Blood (2024) 144 (10): 1116–1126.

https://doi.org/10.1182/blood.2023022608

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis

Woosuk S. Hur, Tomohiro Kawano, Jean Marie N. Mwiza, David S. Paul, Robert H. Lee, Emily G. Clark, Emma G. Bouck, Ananya Dutta, Can Cai, Stephen R. Baker, Martin Guthold, Nigel Mackman, Pierre Mangin, Alisa S. Wolberg, Wolfgang Bergmeier, Matthew J. Flick

Blood (2024) 143 (2): 105–117.

https://doi.org/10.1182/blood.2023020805

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

4D Intravital Imaging Studies Identify Platelets As the Predominant Cellular Procoagulant Surface in Hemostasis

Abigail Ballard, Wolfgang Bergmeier, David Paul, Robert Hugh Lee, Nigel Mackman, Matthew J. Flick, Ellen O'Shaughnessy, David Adalsteinsson, Paul Kim

Blood (2023) 142 (Supplement 1): 2572.

https://doi.org/10.1182/blood-2023-179274

Published: 2023

Journal Articles

Accelerated Platelet Clearance in Mice with Constitutive Store-Operated Calcium Entry Is Independent of Caldag-GEFI/Rap1 Activation

Robert H Lee, Bernhard Nieswandt, Wolfgang Bergmeier

Blood (2022) 140 (Supplement 1): 5542.

https://doi.org/10.1182/blood-2022-163345

Published: 2022

Journal Articles

Identification of Receptors and Signaling Pathways Mediating the Platelet Contribution to Clotting Parameters in Thromboelastography (TEG)

Robert H Lee, Tanvi Rudran, Silvio Antoniak, Alisa S. Wolberg, Wolfgang Bergmeier

Blood (2022) 140 (Supplement 1): 8385.

https://doi.org/10.1182/blood-2022-170017

Published: 2022

Journal Articles

Decreased Platelet Reactivity and Function in a Mouse Model of Pancreatic Cancer

Tomohiro Kawano, Yohei Hisada, Steven P Grover, Wyatt Schug, David Paul, Wolfgang Bergmeier, Nigel Mackman

Blood (2022) 140 (Supplement 1): 5533.

https://doi.org/10.1182/blood-2022-163420

Published: 2022

Journal Articles

Both G protein–coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice

Jean Marie N. Mwiza, Robert H. Lee, David S. Paul, Lori A. Holle, Brian C. Cooley, Bernhard Nieswandt, Wyatt J. Schug, Tomohiro Kawano, Nigel Mackman, Alisa S. Wolberg, Wolfgang Bergmeier

Blood (2022) 139 (21): 3194–3203.

https://doi.org/10.1182/blood.2022015787

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP

Bojing Shao, Christopher Hoover, Huiping Shi, Yuji Kondo, Robert H. Lee, Junmei Chen, Xindi Shan, Jianhua Song, J. Michael McDaniel, Meixiang Zhou, Samuel McGee, Karen Vanhoorelbeke, Wolfgang Bergmeier, José A. López, James N. George, Lijun Xia

Blood (2022) 139 (16): 2523–2533.

https://doi.org/10.1182/blood.2021012896

Published: 2022

Includes: Supplemental data

Journal Articles

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Woosuk S. Hur, David S. Paul, Emma G. Bouck, Oscar A. Negrón, Jean-Marie Mwiza, Lauren G. Poole, Holly M. Cline-Fedewa, Emily G. Clark, Lih Jiin Juang, Jerry Leung, Christian J. Kastrup, Tatiana P. Ugarova, Alisa S. Wolberg, James P. Luyendyk, Wolfgang Bergmeier, Matthew J. Flick

Blood (2022) 139 (9): 1374–1388.

https://doi.org/10.1182/blood.2021012537

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Investigating the Roles of Platelet PAR4 in Hemostasis, Thrombosis and Viral Infection Using a Newly Generated PAR4 Floxed Mouse

Robert H Lee, Tomohiro Kawano, Vanthana Bharathi, David Martinez, Dale O Cowley, Steven P Grover, Nigel Mackman, Wolfgang Bergmeier, Silvio Antoniak

Blood (2021) 138 (Supplement 1): 1000.

https://doi.org/10.1182/blood-2021-151121

Published: 2021

Journal Articles

The Small Gtpase Rap1 in Platelets Is Critical for Arterial but Not Venous Thrombosis in Mice

Jean Mwiza, Robert H Lee, David Paul, Lori A Holle, Brian C Cooley, Alisa S. Wolberg, Wolfgang Bergmeier

Blood (2021) 138 (Supplement 1): 2131.

https://doi.org/10.1182/blood-2021-153362

Published: 2021

Journal Articles

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

Christopher Hoover, Yuji Kondo, Bojing Shao, Michael J. McDaniel, Robert Lee, Samuel McGee, Sidney Whiteheart, Wolfgang Bergmeier, Rodger P. McEver, Lijun Xia

Blood (2021) 137 (20): 2756–2769.

https://doi.org/10.1182/blood.2020010310

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Impact of Platelet Count on Bleeding in the Setting of Anti-Platelet Therapy

Robert Hugh Lee, PhD, Wolfgang Bergmeier, PhD

Blood (2020) 136 (Supplement 1): 18.

https://doi.org/10.1182/blood-2020-142893

Published: 2020

Journal Articles

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg

Blood (2020) 136 (10): 1180–1190.

https://doi.org/10.1182/blood.2020005348

Published: 2020

Includes: Supplemental data

Journal Articles

Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Camille Faes, Anton Ilich, Amandine Sotiaux, Erica M. Sparkenbaugh, Michael W. Henderson, Laura Buczek, Joan D. Beckman, Patrick Ellsworth, Denis F. Noubouossie, Lantarima Bhoopat, Mark Piegore, Céline Renoux, Wolfgang Bergmeier, Yara Park, Kenneth I. Ataga, Brian Cooley, Alisa S. Wolberg, Nigel S. Key, Rafal Pawlinski

Blood (2019) 133 (23): 2529–2541.

https://doi.org/10.1182/blood.2019000424

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Functional redundancy between RAP1 isoforms in murine platelet production and function

Lucia Stefanini, Robert H. Lee, David S. Paul, Ellen C. O'Shaughnessy, Dorsaf Ghalloussi, Christopher I. Jones, Yacine Boulaftali, Kathryn O. Poe, Raymond Piatt, Dan O. Kechele, Kathleen M. Caron, Klaus M. Hahn, Jonathan M. Gibbins, Wolfgang Bergmeier

Blood (2018) 132 (18): 1951–1962.

https://doi.org/10.1182/blood-2018-03-838714

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Calcium-Induced Conformational Changes in EF hands and Autoinhibitory Linker Region are Critical for Catalytic Activity of CalDAG-GEFI Towards the Small GTPase Rap1

Aaron Cook, Wei Deng, PhD, Renhao Li, PhD, John Sondek, PhD, Wolfgang Bergmeier, PhD

Blood (2017) 130 (Supplement 1): 3614.

https://doi.org/10.1182/blood.V130.Suppl_1.3614.3614

Published: 2017

Journal Articles

Murine Studies to Test the Efficacy of Platelet Transfusions in the Management of Platelet Function Disorders

Raymond Piatt, BS, Robert Hugh Lee, PhD, David Paul, PhD, Wolfgang Bergmeier, PhD

Blood (2017) 130 (Supplement 1): 1123.

https://doi.org/10.1182/blood.V130.Suppl_1.1123.1123

Published: 2017

Journal Articles

Phenotype Analysis and Clinical Management in a Large Family with a Novel Truncating Mutation in RASGRP2 , the Caldag-GEFI Encoding Gene

Amrita Desai, MD MPH, Wenche Jy, PhD, Wolfgang Bergmeier, PhD, Mathias Canault, PhD, Marie-Christine Alessi, MD PhD, Paquita Nurden, MD PhD, Yeon-Soong Ahn, MD, Alan T. Nurden, PhD

Blood (2016) 128 (22): 3713.

https://doi.org/10.1182/blood.V128.22.3713.3713

Published: 2016

Journal Articles

Novel mutations in RASGRP2 , which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

María Luisa Lozano, Aaron Cook, José María Bastida, David S. Paul, Gemma Iruin, Ana Rosa Cid, Rosa Adan-Pedroso, José Ramón González-Porras, Jesús María Hernández-Rivas, Sarah J. Fletcher, Ben Johnson, Neil Morgan, Francisca Ferrer-Marin, Vicente Vicente, John Sondek, Steve P. Watson, Wolfgang Bergmeier, José Rivera

Blood (2016) 128 (9): 1282–1289.

https://doi.org/10.1182/blood-2015-11-683102

Published: 2016

Includes: Supplemental data

NARROW

4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model

Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis

4D Intravital Imaging Studies Identify Platelets As the Predominant Cellular Procoagulant Surface in Hemostasis

Accelerated Platelet Clearance in Mice with Constitutive Store-Operated Calcium Entry Is Independent of Caldag-GEFI/Rap1 Activation

Identification of Receptors and Signaling Pathways Mediating the Platelet Contribution to Clotting Parameters in Thromboelastography (TEG)

Decreased Platelet Reactivity and Function in a Mouse Model of Pancreatic Cancer

Both G protein–coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Investigating the Roles of Platelet PAR4 in Hemostasis, Thrombosis and Viral Infection Using a Newly Generated PAR4 Floxed Mouse

The Small Gtpase Rap1 in Platelets Is Critical for Arterial but Not Venous Thrombosis in Mice

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

Impact of Platelet Count on Bleeding in the Setting of Anti-Platelet Therapy

Talin-1 is the principal platelet Rap1 effector of integrin activation

Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Functional redundancy between RAP1 isoforms in murine platelet production and function

Calcium-Induced Conformational Changes in EF hands and Autoinhibitory Linker Region are Critical for Catalytic Activity of CalDAG-GEFI Towards the Small GTPase Rap1

Murine Studies to Test the Efficacy of Platelet Transfusions in the Management of Platelet Function Disorders

Phenotype Analysis and Clinical Management in a Large Family with a Novel Truncating Mutation in RASGRP2 , the Caldag-GEFI Encoding Gene

Novel mutations in RASGRP2 , which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only