Antibodies against human AHF were produced in the rabbit. These antibodies acted as anticoagulants in vitro by inactivating AHF and preventing normal thromboplastin formation. Species specificity and physical properties of the anticoagulant are described. It is postulated that similar anticoagulants occurring in humans are also antibodies produced by AHF immunization.

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© 1956 by American Society of Hematology, Inc.
1956
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