The Vitamin B₁₂ Content of Human Liver Tissue and Its Nutritional Significance : A Comparison Study of Various Age Groups

Range and average values are reported for the vitamin B₁₂ content of liver tissue obtained at autopsy from 132 individuals. Th average value for all age groups was approximately 0.70 γ per Gm. of wet tissues. In cirrhosis the average value was 0.26 γ per Gm. It was concluded that there are no apparent differences in vitamin B₁₂ stores in the various age groups. Also, the amount of vitamin stored is relatively large in terms of requirement and is probably sufficient to last for a period of several years.