H3-thymidine and H3-DL-leucine incorporation in the erythroblasts of the bone marrow from a case of acute and one of chronic Di Guglielmo’s disease was studied. A similar investigation was also carried out with bone marrow from 4 normal subjects. The high resolution of the radioautographic technic employed allowed a comparative study at the cellular and subcellular level.

A definitely lowered thymidine uptake was observed in the cells of acute erythremic myelosis, while increased incorporation of DL-leucine was detected in both the acute and the chronic form of this disease.

This content is only available as a PDF.
© 1960 by American Society of Hematology, Inc.
1960
Sign in via your Institution