Observations on growth and other characteristics of subcutaneously transplanted chloroleukemia in non-inbred rats have been described in this report. This chloroleukemia cytologically is an acute or subacute, not chronic, myelogenous leukemia. Because of serious immunologic differences, the experimental usefulness of subtransferred chloroleukemia is greatly limited. However, myelogenous leukemia in the rat, induced by chemical agents or ionizing radiation, may offer a valuable approach to the study of leukemogenic mechanisms.

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© 1962 by American Society of Hematology, Inc.
1962
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