Platelet survival studies were performed by the radiochromium method in 280 patients. Although various types of patients were studied, markedly accelerated platelet destruction was encountered only in those with ITP. No thrombocytopenic patient was found with accelerated platelet production and changes in platelet count with therapy reflected corresponding changes in survival. The use of surface scanning showed that patients with significant splenic localization were more suitable candidates for splenectomy that those without this localization.

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© 1963 by American Society of Hematology, Inc.
1963
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