Brief Report: Correction of the Hemostatic Defects in Von Willebrand’s Disease

The Pool cryoprecipitate provides an effective source of the factor lacking in the plasma of patients with von Willebrand’s disease which is necessary for a normal bleeding time. Correction of the bleeding time appears to be necessary for control of bleeding in some instances of severe spontaneous hemorrhage. None of the commercially prepared antihemophilic factor concentrates prepared in this country contain adequate amounts of the extremely labile bleeding time factor.