A new hypothesis is proposed for platelet aggregation. The model involves the formation of intermolecular platelet actomyosin bridges between platelet actin and platelet myosin moieties localized on or near the surface of adjacent platelets. These intermolecular platelet actomyosin bridges can then contract in the presence of ATP, drawing the platelets into a tight mass or thrombus.

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© 1969 by American Society of Hematology, Inc.
1969
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