Immunologic Aspects of the Biogenesis of Erythropoietin

SCHOOLEY, JOHN C.; ZANJANI, ESMAIL D.; GORDON, ALBERT S.

doi:10.1182/blood.V35.3.276.276

JOHN C. SCHOOLEY, PH.D.,

JOHN C. SCHOOLEY, PH.D.

Research Physiologist

1Donner Laboratory, Lawrence Radiation Laboratory, University of California, Berkeley, and Laboratory of Experimental Hematology, Department of Biology, New York University, New York, N. Y.

2Lawrence Radiation Laboratory, Donner Laboratory, University of California, Berkeley, Calif.

Search for other works by this author on:

This Site

PubMed

Google Scholar

ESMAIL D. ZANJANI, PH.D.,

ESMAIL D. ZANJANI, PH.D.

Associate Research Scientist

1Donner Laboratory, Lawrence Radiation Laboratory, University of California, Berkeley, and Laboratory of Experimental Hematology, Department of Biology, New York University, New York, N. Y.

3Department of Biology, New York University, New York, N. Y

Search for other works by this author on:

This Site

PubMed

Google Scholar

ALBERT S. GORDON, PH.D.

Professor of Biology

1Donner Laboratory, Lawrence Radiation Laboratory, University of California, Berkeley, and Laboratory of Experimental Hematology, Department of Biology, New York University, New York, N. Y.

3Department of Biology, New York University, New York, N. Y

Search for other works by this author on:

This Site

PubMed

Google Scholar

Blood (1970) 35 (3): 276–281.

https://doi.org/10.1182/blood.V35.3.276.276

Abstract

Immunologic evidence is presented that the interaction of Renal Erythropoietic Factor (REF) and a serum substrate results in the production in vitro of erythropoietin. Antibody capable of neutralizing erythropoietin (ESF) does not combine with either the REF or the serum substrate. Immune serum against the crude REF extract has been produced. This immune serum does not prevent the in vitro action or in vivo production of REF. This failure, however, may result from the diversity of antibodies produced.

This content is only available as a PDF.

1970

Immunologic Aspects of the Biogenesis of Erythropoietin

Abstract

Contents

Data & Figures

Supplemental data

References

Cited By

Email alerts

ASH Publications

American Society of Hematology

Immunologic Aspects of the Biogenesis of Erythropoietin

Abstract

Contents

Data & Figures

Supplemental data

References

Related

Related

Cited By

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only