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Article| July 1, 1949

OBSERVATIONS ON THE EFFECT OF AN ANIMAL PROTEIN FACTOR CONCENTRATE ON PERSONS WITH THE MACROCYTIC ANEMIA OF PERNICIOUS ANEMIA, OF NUTRITIONAL MACROCYTIC ANEMIA AND OF SPRUE, AND ON PERSONS WITH NUTRITIONAL GLOSSITIS

TOM D. SPIES, M.D.,

TOM D. SPIES, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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GUILLERMO GARCIA LOPEZ, M.D.,

GUILLERMO GARCIA LOPEZ, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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FERNANDO MILANES, M.D.,

FERNANDO MILANES, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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ROBERT E. STONE, M.D.,

ROBERT E. STONE, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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RUBEN LOPEZ TOCA, M.D.,

RUBEN LOPEZ TOCA, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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TOMAS ARAMBURU, M.D.,

TOMAS ARAMBURU, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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SAM KARTUS, M.D.

SAM KARTUS, M.D.

1Northwestern University Studies in Nutrition at the Hillman Hospital, Birmingham, Alabama, and at the General Calixto Garcia Hospital, Havana, Cuba, in cooperation with the University of Havana. From the Department of Nutrition and Metabolism, Northwestern University.

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Blood (1949) 4 (7): 819–826.

https://doi.org/10.1182/blood.V4.7.819.819

Abstract

The intramuscular injection of animal protein factor concentrate to 5 cases of pernicious anemia in relapse, 4 cases of nutritional macrocytic anemia in relapse, and 3 cases of tropical sprue in relapse was followed by a positive hematologic response in each case as is illustrated in figures 1, 2, and 4, respectively. The parenteral administration of this material to 3 patients with nutritional glossitis unassociated with anemia was followed by the disappearance of the redness and soreness of the tongue.

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© 1949 by American Society of Hematology, Inc.

1949

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