Congenital Deficiency of Fibrin-stabilizing Factor (Factor XIII): A Report of Four Cases (Two Families) and Family Members

Four patients with congenital deficiency of fibrin-stabilizing factor (factor XIII) from two families have been described. The mother and the sibs in one family and both parents in the other family were found to have varying degrees of factor XIII deficiency. The observations support the hypothesis of autosomal recessive inheritance of factor XIII deficiency.