Macroglobulinemia in a Child With Acute Leukemia

Čejka, Jan; Bollinger, Robert O.; Schuit, Henrica R.E.; Lusher, Jeanne M.; Chang, Chung-Ho; Zuelzer, Wolf W.

doi:10.1182/blood.V43.2.191.191

Jan Čejka, Ph.D.,

Jan Čejka, Ph.D.

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

2Department of Immunochemistry, The Children's Hospital of Michigan, Detroit, Mich. 48201.

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Robert O. Bollinger, Ph.D.,

Robert O. Bollinger, Ph.D.

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

3Department of Electron Microscopy, The Child Research Center of Michigan. Detroit, Mich. 48201.

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Henrica R.E. Schuit,

Henrica R.E. Schuit

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

4Institute for Experimental Gerontology TNO, Rzjswijk (ZH), The Netherlands.

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Jeanne M. Lusher, M.D.,

Jeanne M. Lusher, M.D.

Associate Professor of Pediatrics

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

5Wayne State University School of Medicine, Detroit, Mich. 48207; Associate Hematologist, The Children's Hospital of Michigan, Detroit, Mich. 48201.

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Chung-Ho Chang, M.D.,

Chung-Ho Chang, M.D.

Assistant Pathologist

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

6The Children's Hospital of Michigan, Detroit, Mich. 48201.

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Wolf W. Zuelzer, M.D.

Professor of Pediatrics

1Children’s Hospital of Michigan and The Child Research Center of Michigan, Detroit, Mich. 48201, and the Institute for Experimental Gerontology TNO, Rijswijk, The Netherlands.

7Wayne State University School of Medicine, Detroit, Mich. 48207; Director of The Child Research Center of Michigan, Detroit. Mich. 48201; Chief of Laboratory Medicine, The Children's Hospital of Michigan. Detroit, Mich. 48201.

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Blood (1974) 43 (2): 191–199.

https://doi.org/10.1182/blood.V43.2.191.191

Abstract

A 12-yr-old boy with acute leukemia was found to have paraproteinemia and Bence-Jones proteinuria. The paraprotein was characterized as immunoglobulin M, type κ and the Bence Jones protein as free κ-chains. Increased amounts of β₂-microglobulin were found in the patient’s serum and urine. Electron microscopic and immunofluorescence studies provided evidence of the presence of lymphoid leukemia cells apparently responsible for the production of the paraprotein.

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1974

Macroglobulinemia in a Child With Acute Leukemia

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American Society of Hematology

Macroglobulinemia in a Child With Acute Leukemia

Abstract

Contents

Data & Figures

Supplemental data

References

Related

Related

Cited By

Email alerts

ASH Publications

American Society of Hematology

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