Evaluation of the Oncohaematologic Pathology of Two Oncologics Centers of Buenos Aires, Argentina in the Period between 1995–2005; a Total of 1884 Cases.

Introduction: In the absence of national and regional records of oncohaematologic pathology the information regarding the composition and characterstics of this patients population was evaluated in this two oncologic centers of Buenos Aires.

Results: Of the whole of 1884 patients, the distribution of the pathologies was: Non Hodgkin Lymphoma (NHL): 1040 cases (55,2 %), Hodgkin Lymphoma (HL) 358 (19 %), Leukemia 258 (13,7 %), (chronic lymphatic 105, chronic myeloid 93, acute 52, trycholeukemia 8) Myeloma 131 (6,95 %), thrombocythemia 24 (1,27 %), Myelodysplasia 22 (1,16 %), Polycythemia Vera: 17 (0,90 %), Plasmacytoma 14 (0,74 %), Myelofibrosis 8 (0,42 %), Histiocytosis. 5 (0,26 %), Macroglobulinemia of Waldenstrom 4 (0,2 %), Granulocytic Sarcoma 2 (0,1 %), Dendritics Cells Sarcoma 1 (0,05 %).

The sex distribution was: 982 (52.14 %) males, 902 (47,86 %) females. The range of ages was: 15 to 94 years, with an average of 52,3 years.

Of the whole of 1040 NHL 274 (26,34 %) presented extranodal locations, distributed as follows: skin 63, orbital 37, tonsil 35, oral cavity 17, stomach 16, central nervous system 16 (12 brain), breast 13, soft tissues 12, parothyd 11, cavum 11, bowel 9, testicle 7, paranasal sinuses and bones 6, rectum and lung 3, larynx, uterus and scalp 2, liver, ovary and thyroid gland 1. A whole of 29 patients presented pathology associated with the HIV: 22 NHL and 7 HL.

In the population with HL the average age was 36,7 years, with 38 % younger than 25 years, we do not observe the bimodal curve usually descript.

The predominant histologies: nodular sclerosis 40,7 % and mixed cellularity36,53 % (low frequency of subtypes lymphocitary predominance and lymphocitary depletion). Stage II 44,87 % and stage III 23,71 %. The most frequent locations: cervical 53,2 % and mediastinic 47,11 % (and low frequency of abdominal and inguinal locations).

Conclusions: The frequency of extranodal locations of NHL is similar as the international records. The distribution of the unusual locations is probably biased by the pathologies arrived from specific centers (for example: a center of ophthalmology). The population of HL is characterized by the young age and the supradiaphragmatic locations