Paroxysmal Cold Hemoglobinuria with Positive Treponema Immobilization Test. Report of Case

A case of paroxysmal cold hemoglobinuria is described without a familial or personal history of syphilis. The patient, a 34 year old woman, shows no clinical evidence of syphilis. Numerous serologic tests for syphilis including treponemal immobilization are consistently positive. Despite therapy with penicillin and cortisone the hemolytic disease remains unchanged.