JQ1 and JQ5 impair the GC reaction in murine cGVHD/BO mice. (G) Flow cytometric analysis of single-cell lung suspensions taken from transplanted mice treated with each drug (n = 5/group). (Left) Total plasma cells are CD138+ lymphocytes, (center) immature plasma cells are B220+, CD19+ plasma cells, and (right) mature plasma cells are B220−, CD19− plasma cells. Results show that both drugs significantly reduced the proportion of mature plasma cells in subject lungs.
JQ1 and JQ5 impair the GC reaction in murine cGVHD/BO mice. (G) Flow cytometric analysis of single-cell lung suspensions taken from transplanted mice treated with each drug (n = 5/group). (Left) Total plasma cells are CD138+ lymphocytes, (center) immature plasma cells are B220+, CD19+ plasma cells, and (right) mature plasma cells are B220−, CD19− plasma cells. Results show that both drugs significantly reduced the proportion of mature plasma cells in subject lungs.
In “Materials and methods” on page 2987, an incorrect reagent is listed under “Flow cytometry.” The reagent “anti-CD38 (102718; BioLegend)” should read “anti-CD138 (142514; BioLegend).”
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