Cell extracts possessing considerable proteolytic activity have been obtained from human leukocytes by ultrasonic breakdown or by treatment with surface active agents. Three proteolytic enzymes are present; one with an optimum at approximately pH 8 is inhibited by organophosphorus compounds and resembles chymotrypsin. This enzyme is derived from polymorphonuclear leukocytes. Lymphocytes contain two proteases with pH optima of 3.0 and 5.5, respectively.

This content is only available as a PDF.
© 1960 by American Society of Hematology, Inc.
1960
Sign in via your Institution