Cell Antigens and Cell Specialization : I. A Study of Blood Group Antigens on Normoblasts

This article describes the application of four different models to the study of the presence of specific isoantigens on normoblasts. The findings demonstrate the A, B and H receptors on human normoblasts. These receptors can be shown to be present on the surface of normoblasts in all stages of development and on mitotic normoblasts. These findings suggest that cell isoantigens appear early in cell formation and independently of cell maturation.