Brief Report: Preservation of the Lactic Dehydrogenase Activity of Platelets by Freezing in Dimethylsulfoxide and Plasma

It is concluded that a medium composed of 15 per cent Dimethylsulfoxide and 85 per cent of a mixture of equal parts native plasma and saline effectively preserves platelet lactic acid dehydrogenase activity against slow freezing, storage for 24 hours in temperatures of liquid N₂ and fast thawing. Platelet lysis results in a complete loss of LDH activity.