Quantitative analysis of the chromosomal injuries following in vitro addition of various cytostatic agents to short-term human leukocyte cultures was carried out. The data obtained suggest that the cytogenic action of these various compounds in vitro follows a pattern similar to its action when administered therapeutically to man. The technics used may form the basis of further evaluation of the cytogenetic activity of these various compounds.

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© 1966 by American Society of Hematology, Inc.
1966
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