Ribonuclease has been partially purified from human leukocytes and its properties investigated. The enzyme has a pH optimum between 6 and 6.5. It is equally active with RNA prepared from various sources, attacking phosphodiester bonds adjacent to pyrimidine bases. Activity in myeloblasts or lymphocytes is about one-tenth that of mature granulocytes.

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© 1967 by American Society of Hematology, Inc.
1967
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