Sera from two patients with chronic myelogenous leukemia obtained within one hour after irradiation of the spleen inhibited the growth of a stable cell line derived from the blood of a patient with acute myelogenous leukemia. This inhibitory factor was stable in vitro for one half hour at 55 C. and for 3 days at -80 C.

Serum from a patient with metastatic carcinoma of the breast following thoracic irradiation did not have a similar effect.

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© 1968 by American Society of Hematology, Inc.
1968
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