Evacuation of the fatty marrow cavity results in a sequence of regeneration which is associated with a phase of hemopoiesis. Hemopoietic activity is, however, transient, being replaced by adipose tissue, so that 6 mo after evacuation the marrow is once again fatty. This phase of transient hemopoiesis can be sustained by phenylhydrazine-induced hemolytic stress. Hemolysis per se does not induce significant hemopoietic activity in nonevacuated totally fatty marrow.

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© 1974 by American Society of Hematology, Inc.
1974
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