In the article by Mohri et al, entitled “Clinical Significance of Inhibitors in Acquired von Willebrand Syndrome,” which appeared in the May 15, 1998 (Vol 91, No 10, pp 3623-3629) issue a correction should be noted. In the text on page 3624 under the Results section, in the third paragraph the sentence that reads “was prolonged in 16 out of 20 patients (80%)” should be changed to “was prolonged in 6 out of 8 patients evaluated (75%).” Also, in Table 2 on page 3625 some of the data was incorrectly written. The corrected Table is reprinted below in its entirety.
Case No. . | Diagnosis . | Age . | Sex . | Bleeding Tendency . | Inhibitor . | Blood Type . | Platelets (×104/mm3) . | RIPA (%) . | vWF:AG (%) . | vWF:RCOF (%) . | vWF:AG/ vWF:RCOF . | F:C (%) . | Bleeding Time (min) . | Treatment . | Response to Treatment . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CML | 46 | M | − | + | O | 59.9 | 3 | 27 | 20 | 1.35 | 16 | 12.0 | UD | Yes |
2 | 45 | M | − | − | A | 21.1 | 32 | 68 | 44 | 1.54 | 44 | 13.0 | UD + DDAVP | Yes | |
3 | 39 | F | − | − | B | 12.0 | 37 | 62 | 22 | 2.82 | 48 | 9.5 | UD | Yes | |
4 | 45 | F | − | − | A | 84.7 | 46* | 36 | 22 | 1.63 | 14 | 12.0 | UD | Yes | |
5 | 53 | M | − | − | A | 52.0 | 52* | ND | ND | ND | ND | ND | UD | Yes | |
6 | 46 | F | + | − | O | 61.0 | 55* | ND | ND | ND | ND | ND | UD | No | |
7 | 30 | M | − | − | A | 39.3 | 65* | 46 | 22 | 2.10 | 22 | 6.5 | UD | Yes | |
8 | 46 | M | − | − | B | 66.7 | 18 | 42 | 22 | 1.90 | 48 | 3.0 | UD + DDAVP | Yes | |
9 | PV | 83 | M | − | − | A | 60.7 | 16 | 121 | 40 | 3.03 | 38 | 3.0 | UD + DDAVP | Yes |
10 | 72 | F | + | + | A | 69.5 | 38* | 108 | 20 | 5.40 | 16 | 5.0 | UD + DDAVP | No | |
11 | 48 | F | − | − | B | 78.0 | 56* | 60 | 20 | 3.00 | 14 | 5.0 | UD | Yes | |
12 | ET | 67 | F | − | − | AB | 130.5 | 0 | ND | ND | ND | ND | 13.5 | UD | Yes |
13 | 72 | F | − | − | A | 119.5 | 76* | 65 | 40 | 1.63 | 26 | 9.0 | UD | Yes | |
14 | 58 | F | − | − | A | 124.8 | 73* | 68 | 36 | 1.89 | 24 | 10.5 | UD | Yes | |
15 | AML | 51 | F | + | + | O | 14.6 | 0 | 32 | 20 | 1.60 | 8 | ND | UD | No |
16 | 44 | F | − | − | AB | 12.0 | 7 | 62 | 22 | 2.82 | 18 | 12.5 | UD | Yes | |
17 | AMMoL | 67 | M | − | − | B | 11.9 | 0 | ND | ND | ND | ND | 10.5 | UD | Yes |
18 | ALL | 39 | M | − | − | A | 12.6 | 0 | 48 | 20 | 2.40 | 12 | ND | UD | Yes |
19 | MM IgG-λ | 34 | M | + | + | A | 37.8 | 0 | 28 | 5 | 5.60 | 6 | 15.5 | UD + DDAVP | No |
20 | IgG-κ | 62 | M | + | + | A | 24.3 | 4 | 32 | 9 | 3.56 | 40 | 15.0 | UD | Yes |
21 | IgG-λ | 49 | M | + | + | O | 42.6 | 7 | 7 | 4 | 1.75 | 10 | ND | UD | Yes |
22 | CLL | 64 | F | + | + | A | 23.3 | 21 | 36 | 12 | 3.00 | 15 | 10.5 | UD | No |
23 | 85 | F | − | ND | B | 12.0 | 19 | 22 | 9 | 2.44 | 24 | 6.0 | UD + DDAVP | Yes | |
24 | 52 | F | − | + | A | 17.2 | 7 | 22 | 7 | 3.13 | 9 | 12.5 | UD | Yes | |
25 | NHL | 48 | M | − | − | A | 34.8 | 46* | 69 | 34 | 2.03 | 38 | 6.5 | UD | Yes |
Normal values | 15-34 | 40-80 | 50-155 | 80-120 | 0.9-1.3 | 80-120 | 4-8 |
Case No. . | Diagnosis . | Age . | Sex . | Bleeding Tendency . | Inhibitor . | Blood Type . | Platelets (×104/mm3) . | RIPA (%) . | vWF:AG (%) . | vWF:RCOF (%) . | vWF:AG/ vWF:RCOF . | F:C (%) . | Bleeding Time (min) . | Treatment . | Response to Treatment . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CML | 46 | M | − | + | O | 59.9 | 3 | 27 | 20 | 1.35 | 16 | 12.0 | UD | Yes |
2 | 45 | M | − | − | A | 21.1 | 32 | 68 | 44 | 1.54 | 44 | 13.0 | UD + DDAVP | Yes | |
3 | 39 | F | − | − | B | 12.0 | 37 | 62 | 22 | 2.82 | 48 | 9.5 | UD | Yes | |
4 | 45 | F | − | − | A | 84.7 | 46* | 36 | 22 | 1.63 | 14 | 12.0 | UD | Yes | |
5 | 53 | M | − | − | A | 52.0 | 52* | ND | ND | ND | ND | ND | UD | Yes | |
6 | 46 | F | + | − | O | 61.0 | 55* | ND | ND | ND | ND | ND | UD | No | |
7 | 30 | M | − | − | A | 39.3 | 65* | 46 | 22 | 2.10 | 22 | 6.5 | UD | Yes | |
8 | 46 | M | − | − | B | 66.7 | 18 | 42 | 22 | 1.90 | 48 | 3.0 | UD + DDAVP | Yes | |
9 | PV | 83 | M | − | − | A | 60.7 | 16 | 121 | 40 | 3.03 | 38 | 3.0 | UD + DDAVP | Yes |
10 | 72 | F | + | + | A | 69.5 | 38* | 108 | 20 | 5.40 | 16 | 5.0 | UD + DDAVP | No | |
11 | 48 | F | − | − | B | 78.0 | 56* | 60 | 20 | 3.00 | 14 | 5.0 | UD | Yes | |
12 | ET | 67 | F | − | − | AB | 130.5 | 0 | ND | ND | ND | ND | 13.5 | UD | Yes |
13 | 72 | F | − | − | A | 119.5 | 76* | 65 | 40 | 1.63 | 26 | 9.0 | UD | Yes | |
14 | 58 | F | − | − | A | 124.8 | 73* | 68 | 36 | 1.89 | 24 | 10.5 | UD | Yes | |
15 | AML | 51 | F | + | + | O | 14.6 | 0 | 32 | 20 | 1.60 | 8 | ND | UD | No |
16 | 44 | F | − | − | AB | 12.0 | 7 | 62 | 22 | 2.82 | 18 | 12.5 | UD | Yes | |
17 | AMMoL | 67 | M | − | − | B | 11.9 | 0 | ND | ND | ND | ND | 10.5 | UD | Yes |
18 | ALL | 39 | M | − | − | A | 12.6 | 0 | 48 | 20 | 2.40 | 12 | ND | UD | Yes |
19 | MM IgG-λ | 34 | M | + | + | A | 37.8 | 0 | 28 | 5 | 5.60 | 6 | 15.5 | UD + DDAVP | No |
20 | IgG-κ | 62 | M | + | + | A | 24.3 | 4 | 32 | 9 | 3.56 | 40 | 15.0 | UD | Yes |
21 | IgG-λ | 49 | M | + | + | O | 42.6 | 7 | 7 | 4 | 1.75 | 10 | ND | UD | Yes |
22 | CLL | 64 | F | + | + | A | 23.3 | 21 | 36 | 12 | 3.00 | 15 | 10.5 | UD | No |
23 | 85 | F | − | ND | B | 12.0 | 19 | 22 | 9 | 2.44 | 24 | 6.0 | UD + DDAVP | Yes | |
24 | 52 | F | − | + | A | 17.2 | 7 | 22 | 7 | 3.13 | 9 | 12.5 | UD | Yes | |
25 | NHL | 48 | M | − | − | A | 34.8 | 46* | 69 | 34 | 2.03 | 38 | 6.5 | UD | Yes |
Normal values | 15-34 | 40-80 | 50-155 | 80-120 | 0.9-1.3 | 80-120 | 4-8 |
Abbreviations: UD, treatment of the underlying disease; RIPA, ristocetin-induced platelet aggregation; CML, chronic myelocytic leukemia; PV, polycythemia rubra vera; ET, essential thrombocythemia; AML, acute myelocytic leukemia; AMMoL, acute myelomonocytic leukemia; ALL, acute lymphocytic leukemia; MM, multiple myeloma; CLL, chronic lymphocytic leukemia; NHL, non-Hodgkin’s lymphoma.
Diminution in the slope of the response curve.
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