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Adam J. de Smith, PhD
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Journal Articles

Genetic Determinants of Blood Cell Traits Play a Role in Susceptibility to Acute Lymphoblastic Leukemia

Linda Kachuri, PhD MPH, Soyoung Jeon, BSc, Andrew T. DeWan, PhD, Catherine Metayer, MD PhD, John S. Witte, PhD, Xiaomei Ma, PhD, Charleston W. K. Chiang, PhD, Joseph L. Wiemels, PhD, Adam J. de Smith, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-141443
Published: 2020
Journal Articles

Genetic Alterations Precede DNA Methylation Changes in Juvenile Myelomonocytic Leukemia

Astrid Behnert, MD, Julia Meyer, PhD, Jahan-Yar Parsa, PhD, Aaron Hechmer, PhD, Mignon L. Loh, MD, Adam B. Olshen, PhD, Adam J. de Smith, PhD, Elliot Stieglitz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-143443
Published: 2020
Journal Articles

The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies

Joseph L. Wiemels, PhD, Ivo S Muskens, Shaobo Li, Priyatama Pandey, Ritu Roy, PhD, Helen M Hansen, BSc, Kimberly D Siegmund, PhD, Beth A Mueller, PhD, Xiaomei Ma, PhD, Catherine Metayer, MD PhD, Adam J de Smith, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2510.
https://doi.org/10.1182/blood-2019-131455
Published: 2019
Journal Articles

Germline GAB2 Mutations in Childhood Acute Lymphoblastic Leukemia

Adam J de Smith, PhD, Geneviève Lavoie, PhD, Kyle M Walsh, PhD, Sumeet Aujla, BSc, Erica Evans, BSc, Helen M Hansen, BSc, Ivan Smirnov, PhD, Alice Y Kang, MPH, Martin Zenker, MD, John J Ceremsak, BSc, Elliot Stieglitz, MD, Roberta McKean-Cowdin, PhD, Catherine Metayer, PhD, Philippe P Roux, PhD, Joseph L Wiemels, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 388.
https://doi.org/10.1182/blood-2018-99-119235
Published: 2018
Journal Articles

Large Multi-Ethnic Genome Wide Association Study Reveals Novel Genetic Associations with Childhood Acute Lymphoblastic Leukemia at Chromosomes 8q24 and 17q12

Adam J. de Smith, PhD, Kyle M. Walsh, PhD, Stephen S. Francis, PhD, Semira Gonseth, MD, Helen M. Hansen, BSc, Ivan Smirnov, PhD, Lisa Barcellos, PhD, Rong Wang, PhD, Andrew T. DeWan, PhD, Catherine Metayer, PhD, Xiaomei Ma, MD PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 30.
https://doi.org/10.1182/blood.V130.Suppl_1.30.30
Published: 2017
Journal Articles

Somatic and Germline Mutational Heterogeneity in High Hyperdiploid Acute Lymphoblastic Leukemia

Adam J de Smith, PhD, Kyle M Walsh, PhD, Ivan Smirnov, PhD, Sumeet Aujla, Erica Sanders, Hansen M Helen, Catherine Metayer, PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2016) 128 (22): 1727.
https://doi.org/10.1182/blood.V128.22.1727.1727
Published: 2016
Journal Articles

A Novel Functional Polymorphism in the CCAAT/Enhancer Binding Protein (C/EBP), Epsilon (CEBPE) Gene Promoter Influences Acute Lymphoblastic Leukemia Risk Via Interaction with IKZF1

Kyle M. Walsh, PhD, Adam J. de Smith, PhD, Jianqiao Xiao, Marcus O. Muench, Marina Fomin, Helen M. Hansen, Catherine Metayer, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 489.
https://doi.org/10.1182/blood.V124.21.489.489
Published: 2014
Journal Articles

Missense SNP rs3731249 Explains the CDKN2A Association with Childhood ALL and Shows Risk Allele Selection in Tumors with Somatic CDKN2A Alterations

Adam J. de Smith, PhD, Kyle M. Walsh, PhD, Helen M. Hansen, Lisa F. Barcellos, PhD, Anand P. Chokkalingam, PhD, Robert B. Jenkins, MD PhD, Margaret R. Wrensch, PhD, John K. Wiencke, PhD, Catherine Metayer, MD PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 129.
https://doi.org/10.1182/blood.V124.21.129.129
Published: 2014
Journal Articles

Two-Track Epigenetic Remodeling and Backtracking to Embryonic Stem Cell Bivalency in B-Cell Acute Lymphoblastic Leukemias

Seung-Tae Lee, MD, Marcus O. Muench, Marina Fomin, Jianqiao Xiao, Mi Zhou, MD PhD, Adam J. de Smith, PhD, José Martín-Subero, Simon Heath, E. Andres Houseman, Ritu Roy, Margaret R. Wrensch, PhD, John K. Wiencke, PhD, Catherine Metayer, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 3557.
https://doi.org/10.1182/blood.V124.21.3557.3557
Published: 2014