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Journal Articles

Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor

Natalia Baran, PhDMD, Alessia Lodi, PhD, Yogesh Dhungana, PhD, Shannon RENEE Sweeney, PhD, Pandey Renu, PhD, Shelley Herbrich, PhD, Fieke W Hoff, BSc, Anna Skwarska, PhD, Mecit Kaplan, MS, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, MSc, Marc Warmoes, PhD, Shanti Rojas-Sutterlin, PhD, Andre Haman, PhD, Diogo Troggian Veiga, PhD, Ken Furudate, DDM, PhD, Helen Ma, MS, Karine Harutyunyan, PhD, Wentao Yang, Mihai Gagea, MDPhD, Di Du, PhD, May Daher, Luciana Melo Garcia, MD, Sujan Piya, PhD, Vivian Ruvolo, MS, Sriram Shanmugavelandy, Ningping Feng, PhD, Jason P Gay, MS, Ondrej Havranek, MDPhD, Jared Henderson, MS, Katarzyna Tomczak, PhD, Marcin Kaminski, PhD, Daniel Herranz, PharmD, Adolfo Ferrando, MD, PhD, Elias Jabbour, MD, Maria E Di Francesco, PhD, David T. Teachey, MD, Terzah M. Horton, MD PhD, Katayoun Rezvani, MD PhD, Jun J. Yang, PhD, Steven M. Kornblau, MD, Eric Davis, MD, Koichi Takahashi, MD PhD, Michael Andreeff, MD PhD, Joseph R Marszalek, PhD, Philip Lorenzi, PhD, Jiyang Yu, PhD, Stefano Tiziani, PhD, Trang Hoang, PhD, Marina Konopleva, MD PhD

Blood (2020) 136 (Supplement 1): 18–20.

https://doi.org/10.1182/blood-2020-136801

Published: 2020

Journal Articles

Mechanisms of Therapeutic Response to Tipifarnib in a Mouse Model of Angioimmunoblastic T-Cell Lymphoma

Jose Rodriguez Cortes, Anisha Cooke, Aidan Quinn, Bobby B Shih, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo Ferrando, MD, PhD, Teresa Palomero, PhD

Blood (2020) 136 (Supplement 1): 9.

https://doi.org/10.1182/blood-2020-135838

Published: 2020

Journal Articles

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Clara Reglero, PhD, Dieck L. Chelsea, PhD, Jui Wan Loh, Hossein Khiabanian, PhD, Adolfo Ferrando, MD, PhD

Blood (2019) 134 (Supplement_1): 728.

https://doi.org/10.1182/blood-2019-128615

Published: 2019

Journal Articles

Targeting BCL-XL By Protac DT2216 Effectively Eliminates Leukemia Cells in T-ALL Pre-Clinical Models

Qi Zhang, PhD, Sajid Khan, PhD, Xuan Zhang, Vinitha Mary Kuruvilla, MSc, Sanaz Ghotbaldini, Julia Wells, PhD, Natalia Baran, PhDMD, Tianyu Cai, PhD, Lina Han, PhD, Adolfo Ferrando, MD, PhD, Yong-Mi Kim, MD MPH, PhD, Guangrong Zheng, Daohong Zhou, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 3870.

https://doi.org/10.1182/blood-2019-124744

Published: 2019

Journal Articles

Notch Signaling Is Required for Mast Cell Development In the Zebrafish and May Represent a Novel Therapeutic Strategy In Systemic Mastocytosis

Sahar I Da'as, MSc, Tugce B Balci, MD, Eileen R McBride, MD, FRCP(C), Lauren C Klein, BSc, Evelyn M Teh, PhD, Adolfo Ferrando, MD, PhD, Jason N Berman, MD

Blood (2010) 116 (21): 930.

https://doi.org/10.1182/blood.V116.21.930.930

Published: 2010

Journal Articles

High-Throughput Mutational Profiling In AML: Mutational Analysis of the ECOG E1900 Trial

Blood (2010) 116 (21): 851.

https://doi.org/10.1182/blood.V116.21.851.851

Published: 2010

Journal Articles

Oncogenic AKT Signaling Negatively Regulates Glucocorticoid Receptor Function to Promote Glucocorticoid Resistance In T Cell Acute Lymphoblastic Leukemia

Erich Piovan, MD, PhD, Jiyang Yu, PhD, Pedro Real, PhD, Gawinowicz Mary Ann, PhD, Andrea Califano, PhD, Adolfo Ferrando, MD, PhD

Blood (2010) 116 (21): 11.

https://doi.org/10.1182/blood.V116.21.11.11

Published: 2010

Journal Articles

BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia

Blood (2010) 116 (21): 471.

https://doi.org/10.1182/blood.V116.21.471.471

Published: 2010

Journal Articles

Identification of a Novel T-ALL Entity with NKX2-1/NKX2-2 Rearrangements

Blood (2010) 116 (21): 3139.

https://doi.org/10.1182/blood.V116.21.3139.3139

Published: 2010

Journal Articles

Identification of NOTCH1-Controlled Transcriptional Programs In Human T-Cell Development

Giusy Della Gatta, PhD, Alberto Ambesi Impiombato, PhD, Teresa Palomero, PhD, Valeria Tosello, PhD, Pavel Sumazin, PhD, Andrea Califano, PhD, Adolfo Ferrando, MD, PhD

Blood (2010) 116 (21): 2495.

https://doi.org/10.1182/blood.V116.21.2495.2495

Published: 2010

Journal Articles

Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-ALL.

Adolfo Ferrando, MD, PhD, Teresa Palomero, PhD, Maria Luisa Sulis, MD, Maria Cortina, PhD, Pedro J. Real, PhD, Kelly Barnes, Maria Ciofani, PhD, Esther Caparros, PhD, Sherrie L. Perkins, MD, Govind Bhagat, MD, Archana Mishra, MD, Giuseppe Basso, MD, Ramon Parsons, MD, PhD, Juan Carlos Zúniga-Pflücker, PhD, Maria Dominguez, PhD

Blood (2007) 110 (11): 5.

https://doi.org/10.1182/blood.V110.11.5.5

Published: 2007

Journal Articles

FBW7 E3-Ligase Mutations Are Associated with T Cell Leukemia.

Silvia Buonamici, PhD, Benjamin J. Thompson, Maria L. Sulis, MD, Teresa Palomero, PhD, Adolfo Ferrando, MD, PhD, Iannis Aifantis, PhD

Blood (2007) 110 (11): 4284.

https://doi.org/10.1182/blood.V110.11.4284.4284

Published: 2007

Journal Articles

Inhibition of NOTCH1 Signaling Reverses Glucocorticoid Resistance in T-ALL.

Pedro J. Real, PhD, Valeria Tosello, PhD, Walden Ai, PhD, Teresa Palomero, PhD, Maria Luisa Sulis, PhD, Mireia Castillo, MD, Irene Homminga, PhD, Jules Meijerink, PhD, Carlos Cordon-Cardo, MD, PhD, Adolfo Ferrando, MD, PhD

Blood (2007) 110 (11): 151.

https://doi.org/10.1182/blood.V110.11.151.151

Published: 2007

Journal Articles

A Novel Class of Activating Mutations in NOTCH1 in T-ALL.

Maria Luisa Sulis, MD, Odette Williams, Valeria Tosello, PhD, Sasikala Pallippukam, PhD, Teresa Palomero, PhD, Kelly Barnes, Jules Meijerink, PhD, Adolfo Ferrando, MD, PhD

Blood (2007) 110 (11): 694.

https://doi.org/10.1182/blood.V110.11.694.694

Published: 2007

Journal Articles

Identification of Oncogenic Pathways of T-Acute Lymphoblastic Leukemia (T-ALL) through Gene Expression Profiling of Mouse Tumor Models.

Maria Luisa Sulis, MD, Teresa Palomero, PhD, Pedro J. Real, PhD, Kelly C. Barnes, Peter Aplan, MD, Neal Copeland, PhD, Dave Utpal, MD, Fotini Gounari, PhD, Gerald Grosveld, MD, Dietmar J. Kappes, PhD, Barbara Kee, PhD, Michelle Kelliher, PhD, Jack Lenz, PhD, Christine Richardson, PhD, Adolfo Ferrando, MD PhD

Blood (2006) 108 (11): 2234.

https://doi.org/10.1182/blood.V108.11.2234.2234

Published: 2006

Journal Articles

Microarray Analyses in a Case-Control Cohort of T-ALL Samples Identifies Gene Signature of Potential Prognostic Significance.

Stuart S. Winter, MD, Hadya Khawaja, Zeyu Jiang, PhD, Charles Kooperberg, PhD, Adolfo Ferrando, MD, Thomas Look, MD, Richard S. Larson, MD, PhD

Blood (2005) 106 (11): 1448.

https://doi.org/10.1182/blood.V106.11.1448.1448

Published: 2005

NARROW

Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor

Mechanisms of Therapeutic Response to Tipifarnib in a Mouse Model of Angioimmunoblastic T-Cell Lymphoma

Post-Translational Mechanisms of NT5C2 Activation As Non-Genetic Drivers of Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia

Targeting BCL-XL By Protac DT2216 Effectively Eliminates Leukemia Cells in T-ALL Pre-Clinical Models

Notch Signaling Is Required for Mast Cell Development In the Zebrafish and May Represent a Novel Therapeutic Strategy In Systemic Mastocytosis

High-Throughput Mutational Profiling In AML: Mutational Analysis of the ECOG E1900 Trial

Oncogenic AKT Signaling Negatively Regulates Glucocorticoid Receptor Function to Promote Glucocorticoid Resistance In T Cell Acute Lymphoblastic Leukemia

BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia

Identification of a Novel T-ALL Entity with NKX2-1/NKX2-2 Rearrangements

Identification of NOTCH1-Controlled Transcriptional Programs In Human T-Cell Development

Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-ALL.

FBW7 E3-Ligase Mutations Are Associated with T Cell Leukemia.

Inhibition of NOTCH1 Signaling Reverses Glucocorticoid Resistance in T-ALL.

A Novel Class of Activating Mutations in NOTCH1 in T-ALL.

Identification of Oncogenic Pathways of T-Acute Lymphoblastic Leukemia (T-ALL) through Gene Expression Profiling of Mouse Tumor Models.

Microarray Analyses in a Case-Control Cohort of T-ALL Samples Identifies Gene Signature of Potential Prognostic Significance.

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American Society of Hematology

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American Society of Hematology

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