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Journal Articles

Synergistic Platelet Inhibitory Effects of Riociguat and Nitric Oxide Are Decreased By Protein Binding

Yifeng WU, MD, Alan D Michelson, MD, Andrew L Frelinger, III, PhD

Blood (2018) 132 (Supplement 1): 4971.

https://doi.org/10.1182/blood-2018-99-117070

Published: 2018

Journal Articles

Elipsis: A Longitudinal Study of Electronic Patient-Reported Outcomes, Actigraphy and Biomarkers to Identify and Assess at-Home Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Michael U. Callaghan, Patrick C. Hines, MD PhD, Debra D Pittman, MS, David Beidler, PhD, Denis Rybin, PhD, Ahmar Urooj Zaidi, MD BSc, Jennell White, PhD, Ke Liu, PhD, Bryan Hannan, MS, Xiufeng Gao, MD, Andreas M Pleil, PhD, Alexandra Barsdorf, PhD, Martin David, Pharm D, Melanie Simmons, PMP, PSM, Andrew L Frelinger, III, PhD, Alan D Michelson, MD, Nick Clarke, PhD, Robert J Charnigo, MS

Blood (2017) 130 (Supplement 1): 973.

https://doi.org/10.1182/blood.V130.Suppl_1.973.973

Published: 2017

Journal Articles

A Phase 1b, Randomized, Double-Blind, Placebo-Controlled Study of PF-04447943 in Patients with Stable Sickle Cell Disease: Changes in Exploratory Biomarkers

Robert J Charnigo, MS, Jo Howard, MBBCh, David Beidler, PhD, Denis Rybin, PhD, Beesan Tan, PhD, Alan D Michelson, MD, Andrew L Frelinger, III, PhD, Nicholas Clarke, PhD

Blood (2017) 130 (Supplement 1): 974.

https://doi.org/10.1182/blood.V130.Suppl_1.974.974

Published: 2017

Journal Articles

Mass Cytometry of Platelets: Simultaneous Functional and Phenotypic Analysis of Multiple Surface Markers in Healthy Subjects and Patients with Inherited Platelet Disorders Reveals Novel Platelet Sub-Populations

Thomas A. Blair, PhD, Alan D Michelson, MD, Andrew L Frelinger, III, PhD

Blood (2017) 130 (Supplement 1): 2311.

https://doi.org/10.1182/blood.V130.Suppl_1.2311.2311

Published: 2017

Journal Articles

Platelet Function in Thrombocytopenic Patients with Chronic Liver Disease

Elena Smolensky Koganov, PhD, Sabrina L Carmichael, BS, Emma E Forde, BS, Andrew L Frelinger, III, PhD, Alan D Michelson, MD

Blood (2017) 130 (Supplement 1): 2314.

https://doi.org/10.1182/blood.V130.Suppl_1.2314.2314

Published: 2017

Journal Articles

Avatrombopag, a Novel Thrombopoietin Receptor Agonist, Increases Platelet Counts without Increasing Platelet Activation in Patients with Thrombocytopenia Due to Chronic Liver Disease

Andrew L Frelinger, III, PhD, Elena Smolensky Koganov, PhD, Emma E Forde, BS, Sabrina L Carmichael, BS, Alan D Michelson, MD

Blood (2017) 130 (Supplement 1): 290.

https://doi.org/10.1182/blood.V130.Suppl_1.290.290

Published: 2017

Journal Articles

GLS-409, a Synergistic Inhibitor of Both P2Y 1 and P2Y 12 : Efficacy in a Canine Model of Recurrent Coronary Thrombosis and Reversibility of Human Platelet Inhibition

Elena Smolensky Koganov, PhD, Alan D Michelson, MD, Ivan B Yanachkov, PhD, Milka I Yanachkova, PhD, George E Wright, PhD, Karin Przyklenk, PhD, Andrew L Frelinger, III, PhD

Blood (2017) 130 (Supplement 1): 630.

https://doi.org/10.1182/blood.V130.Suppl_1.630.630

Published: 2017

Journal Articles

The Platelet Phenotype of Children with ITP Is Consistent over Time and Is Associated with Both Concurrent and Subsequent Bleeding Severity

Andrew L. Frelinger, III, PhD, Rachael F Grace, MD, Anja J. Gerrits, PhD, Sabrina L Carmichael, BS, Emma E Forde, BS, Alan D. Michelson, MD

Blood (2016) 128 (22): 2550.

https://doi.org/10.1182/blood.V128.22.2550.2550

Published: 2016

Journal Articles

Association Of Platelet Function Markers, Independent Of Platelet Count, With Bleeding Score In Patients With Immune Thrombocytopenia

Andrew L. Frelinger, III, PhD, Anja J Gerrits, PhD, Michelle A. Berny-Lang, PhD, Travis Brown, Sabrina L. Carmichael, BS, Ellis J. Neufeld, MD, PhD, Alan D. Michelson, MD, Rachael F. Grace, MD

Blood (2013) 122 (21): 3534.

https://doi.org/10.1182/blood.V122.21.3534.3534

Published: 2013

Journal Articles

Effects Of Eltrombopag On Thrombocytopenia, Platelet Function and Bleeding In Patients With Wiskott-Aldrich Syndrome/X-Linked Thrombocytopenia

Anja J Gerrits, PhD, Emily Leven, Andrew L. Frelinger, III, PhD, Michelle A. Berny-Lang, PhD, Hannah Tamary, MD, Shoshana Revel-Vilk, MD, MSc, Sabrina L. Carmichael, BS, W. Beau Mitchell, MD, Alan D. Michelson, MD, James B Bussel, MD

Blood (2013) 122 (21): 3536.

https://doi.org/10.1182/blood.V122.21.3536.3536

Published: 2013

Journal Articles

Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function

Andrew L. Frelinger, III, PhD, Deepak L. Bhatt, MD, MPH, Ronald D. Lee, PhD, Darcy J. Mulford, PhD, Jingtao Wu, PhD, Sai Nudurupati, PhD, Anu Nigam, MS, Michael Lampa, BS, Julie K. Brooks, MS, Marc R. Barnard, MS, Alan D. Michelson, MD

Blood (2012) 120 (21): 4356.

https://doi.org/10.1182/blood.V120.21.4356.4356

Published: 2012

Journal Articles

Platelet Activation and Inhibition in Sickle Cell Disease (PAINS) Study

Andrew L. Frelinger, III, PhD, Joseph A. Jakubowski, PhD, Julie K. Brooks, MS, Sabrina L. Zayas, BS, Michelle A. Berny-Lang, PhD, Marc R. Barnard, MS, Matthew M. Heeney, MD, Alan D. Michelson, MD

Blood (2012) 120 (21): 5147.

https://doi.org/10.1182/blood.V120.21.5147.5147

Published: 2012

Journal Articles

Platelet Spreading Requires Exocytosis of a Subpopulation of α-Granules Expressing VAMP-7,

Robert C. Flaumenhaft, MD, PhD, Alan D. Michelson, MD, Christian G. Peters, Ph.D.

Blood (2011) 118 (21): 3248.

https://doi.org/10.1182/blood.V118.21.3248.3248

Published: 2011

Journal Articles

In Vivo Platelet Activation and Its In Vitro Inhibition by Prasugrel's Active Metabolite In Adolescents with Sickle Cell Disease

Andrew L. Frelinger, III, PhD, Joseph A. Jakubowski, PhD, Julie K. Brooks, MS, Anu Nigam, MS, Michelle A. Berny-Lang, Ph.D., Marc R. Barnard, MS, Matthew M. Heeney, MD, Alan D. Michelson, MD

Blood (2011) 118 (21): 2141.

https://doi.org/10.1182/blood.V118.21.2141.2141

Published: 2011

Journal Articles

Platelet Function and Response to Thrombopoietin Mimetics In Wiskott-Aldrich Syndrome/X-Linked Thrombocytopenia.

James B. Bussel, MD, Andrew L Frelinger, III, PhD, William B Mitchell, MD, Mariana P Pinheiro, MD, Marc R Barnard, MS, Michael Lampa, BS, Bethan Psaila, MD, PhD, Nayla Boulad, BA, Hannah Tamary, MD, Alan D. Michelson, MD

Blood (2010) 116 (21): 1429.

https://doi.org/10.1182/blood.V116.21.1429.1429

Published: 2010

Journal Articles

In Vivo Effects of Eltrombopag on Human Platelet Function.

Bethan Psaila, MD, James B. Bussel, MD, Matthew D. Linden, PhD, You Fu Li, MD, Marc R. Barnard, MS, Chinara M. Tate, BA, Lemke K. Page, MD, Andrew L. Frelinger, PhD, Alan D. Michelson, MD

Blood (2007) 110 (11): 1301.

https://doi.org/10.1182/blood.V110.11.1301.1301

Published: 2007

Journal Articles

Comparison of Platelet Function and Bleeding in Thrombocytopenic Patients with Immune Thrombocytopenic Purpura (ITP) and Chemotherapy-Induced Thrombocytopenia (CIT).

Bethan Psaila, MD, James B. Bussel, MD, Matthew D. Linden, PhD, You Fu Li, MD, Marc R. Barnard, MS, Chinara M. Tate, BA, Lemke K. Page, MD, Eric J. Feldman, MD, Andrew L. Frelinger, PhD, Alan D. Michelson, MD

Blood (2007) 110 (11): 2094.

https://doi.org/10.1182/blood.V110.11.2094.2094

Published: 2007

Journal Articles

Detection and Mechanisms of GPIIb-IIIa Antagonist Induced Thrombocytopenia: Role for Antibody Induced Platelet Activation.

Matthew D. Linden, PhD, Andrew L. Frelinger, PhD, Mark I. Furman, MD, Lori A. Krueger, MLT ART, Youfu Li, MD, Marsha L. Fox, MS, RN, Annette Hughes, John Lown, MD, Marc R. Barnard, MS, Karin Przyklenk, PhD, Alan D. Michelson, MD

Blood (2005) 106 (11): 1654.

https://doi.org/10.1182/blood.V106.11.1654.1654

Published: 2005

Journal Articles

Patients with Coronary Artery Disease Have an Increased Incidence of Aspirin Resistance: Association of PFA-100 Closure Time with Clinical Findings.

Andrew L. Frelinger, PhD, Matthew D. Linden, PhD, Mark I. Furman, MD, Marsha L. Fox, RN, Marc R. Barnard, MS, Youfu Li, MD, Kurt Barringhaus, MD, Karin Przyklenk, PhD, Alan D. Michelson, MD

Blood (2004) 104 (11): 1859.

https://doi.org/10.1182/blood.V104.11.1859.1859

Published: 2004

NARROW

Synergistic Platelet Inhibitory Effects of Riociguat and Nitric Oxide Are Decreased By Protein Binding

Elipsis: A Longitudinal Study of Electronic Patient-Reported Outcomes, Actigraphy and Biomarkers to Identify and Assess at-Home Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

A Phase 1b, Randomized, Double-Blind, Placebo-Controlled Study of PF-04447943 in Patients with Stable Sickle Cell Disease: Changes in Exploratory Biomarkers

Mass Cytometry of Platelets: Simultaneous Functional and Phenotypic Analysis of Multiple Surface Markers in Healthy Subjects and Patients with Inherited Platelet Disorders Reveals Novel Platelet Sub-Populations

Platelet Function in Thrombocytopenic Patients with Chronic Liver Disease

Avatrombopag, a Novel Thrombopoietin Receptor Agonist, Increases Platelet Counts without Increasing Platelet Activation in Patients with Thrombocytopenia Due to Chronic Liver Disease

GLS-409, a Synergistic Inhibitor of Both P2Y 1 and P2Y 12 : Efficacy in a Canine Model of Recurrent Coronary Thrombosis and Reversibility of Human Platelet Inhibition

The Platelet Phenotype of Children with ITP Is Consistent over Time and Is Associated with Both Concurrent and Subsequent Bleeding Severity

Association Of Platelet Function Markers, Independent Of Platelet Count, With Bleeding Score In Patients With Immune Thrombocytopenia

Effects Of Eltrombopag On Thrombocytopenia, Platelet Function and Bleeding In Patients With Wiskott-Aldrich Syndrome/X-Linked Thrombocytopenia

Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Non-Compliance, Diet, Smoking, Co-Medications (including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function

Platelet Activation and Inhibition in Sickle Cell Disease (PAINS) Study

Platelet Spreading Requires Exocytosis of a Subpopulation of α-Granules Expressing VAMP-7,

In Vivo Platelet Activation and Its In Vitro Inhibition by Prasugrel's Active Metabolite In Adolescents with Sickle Cell Disease

Platelet Function and Response to Thrombopoietin Mimetics In Wiskott-Aldrich Syndrome/X-Linked Thrombocytopenia.

In Vivo Effects of Eltrombopag on Human Platelet Function.

Comparison of Platelet Function and Bleeding in Thrombocytopenic Patients with Immune Thrombocytopenic Purpura (ITP) and Chemotherapy-Induced Thrombocytopenia (CIT).

Detection and Mechanisms of GPIIb-IIIa Antagonist Induced Thrombocytopenia: Role for Antibody Induced Platelet Activation.

Patients with Coronary Artery Disease Have an Increased Incidence of Aspirin Resistance: Association of PFA-100 Closure Time with Clinical Findings.

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American Society of Hematology

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American Society of Hematology

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