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Alice Melão
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Journal Articles

Dependence of IL-7R-Mediated Signaling on Sphingosine Kinase Activity in Acute Lymphoblastic Leukemia, but Not Healthy Lymphoid Cells, Is an Exploitable Therapeutic Vulnerability

Marta B Fernandes, Alice Melão, Tatiana Araújo, Ana Cachucho, David R Adams, Jeongah Oh, Afonso R M Almeida, Federico Torta, Vasco Barreto, Susan Pyne, Timothy Hla, Nigel J Pyne, Joao T Barata
Journal: Blood
Blood (2023) 142 (Supplement 1): 38.
https://doi.org/10.1182/blood-2023-186707
Published: 2023
Journal Articles

IL-7 Activates a STAT5/PIM1 Axis to Promote T-Cell Acute Lymphoblastic Leukemia Proliferation and Viability in a Bcl-2-Independent Manner

Ribeiro Daniel, PhD, Alice Melão, Msc, Ruben van Boxtel, PhD, Cristina Santos, PhD, Ana Silva, PhD, Milene C Silva, PhD, Bruno António Cardoso, PhD, Paul J. Coffer, PhD Prof, Joao Barata, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 914.
https://doi.org/10.1182/blood-2018-99-113778
Published: 2018
Journal Articles

CK2 Basal Activity Regulates IL-7-Mediated JAK/STAT and PI3K/Akt Pathway Activation and Pro-Survival Effects in T-Cell Acute Lymphoblastic Leukemia Cells

Alice Melao, Ana Girio, PhD, Joao T. Barata, PhD
Journal: Blood
Blood (2012) 120 (21): 1242.
https://doi.org/10.1182/blood.V120.21.1242.1242
Published: 2012
Journal Articles

In Vitro and in Vivo Targeting of Chronic Lymphocytic Leukemia Using CX-4945, a Clinical-Stage CK2-Specific Inhibitor.

Leila R. Martins, DVM, Paulo Lúcio, MD, PhD, Alice Melao, Bruno A. Cardoso, PhD, Ryan Stansfield, Denis Drygin, PhD, Maria Gomes Silva, MD, PhD, Joao T. Barata, PhD
Journal: Blood
Blood (2012) 120 (21): 2897.
https://doi.org/10.1182/blood.V120.21.2897.2897
Published: 2012