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Alicia Benítez Rondán
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Journal Articles

BMS-986458, a first-in-class, highly selective, and potent ligand-directed degrader (LDD) of B-cell lymphoma 6 (BCL6) combined with T-cell engagers (TCEs) demonstrates preclinical synergistic antitumor efficacy for the treatment of B-cell non-Hodgkin lymphoma (NHL)

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Gauri Deb, Alicia Benítez Rondán, Kelven Burnett, Hugo Olmedo, Pako Lopez Acosta, Ana Isabel Moreno Bernal, Steven Nguyen, Paola Castiglioni, Suzanne Coberly, Carla Guarinos, Lynda Groocock, Rama Krishna Narla, Antonia Lopez-Girona, Soraya Carrancio, Neil Bence
Journal: Blood
Blood (2025) 146 (Supplement 1): 5090.
https://doi.org/10.1182/blood-2025-5090
Published: 2025
Journal Articles

BMS-986458, a first-in-class, bifunctional cereblon-dependent ligand-directed degrader of B-cell lymphoma 6 (BCL6) in patients with Relapsed/Refractory (R/R) non-Hodgkin lymphoma (NHL): Updated results from the Phase 1 dose escalation study

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Franck Morschhauser, David Qualls, Jennifer Lue, Anastasios Stathis, Marcel Nijland, Avyakta Kallam, Jörg Bittenbring, Guillaume Cartron, Noémie Lang, Marjolein Van Der Poel, Loic Ysebaert, Vladan Vucinic, Alejandro Martin Garcia-Sancho, Antonio Rueda Dominguez, Noelia Purroy, Berengere De Moucheron, Xiaosong Li, Carla Guarinos, Joseph Burnett, Alicia Benítez Rondán, Michael Pourdehnad, Jessica Voetsch, Diego Sobradillo, Jean-Marie Michot
Journal: Blood
Blood (2025) 146 (Supplement 1): 480.
https://doi.org/10.1182/blood-2025-480
Published: 2025
Journal Articles

BMS-986458 a Potential First-in-Class, Highly Selective, Potent and Well Tolerated BCL6 Ligand Directed Degrader (LDD) Demonstrates Multi-Modal Anti-Tumor Efficacy for the Treatment of B-Cell Non-Hodgkin's Lymphoma

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Lynda Groocock, Gauri Deb, Jinyi Zhu, Jim Gamez, Paola Castiglioni, Manuel Sanchez-Castillo, Justin Schumacher, Alicia Benitez Rondan, Diana Jankeel, Karla Martinez-Garcia, Scott Wood, Andy Christoforou, Carla Guarinos, Wei Zhang, Rama Krishna Narla, Christoph W. Zapf, Soraya Carrancio, Daniel W. Pierce, Mark Rolfe, Neil Bence, Antonia Lopez-Girona, Deborah S. Mortensen
Journal: Blood
Blood (2024) 144 (Supplement 1): 957.
https://doi.org/10.1182/blood-2024-210951
Published: 2024