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Journal Articles

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

David Muench, BS, Kyle Ferchen, BS, Chinavenmeni S. Velu, PhD, Kith Pradhan, PhD, Kashish Chetal, MS, Clemencia Colmenares, PhD, Amit Verma, MD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD

Blood (2018) 132 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2018-99-119441

Published: 2018

Journal Articles

Causes and Predictors of Early Mortality in HIV-Positive and HIV-Negative Patients with Diffuse Large B-Cell Lymphoma

Sakshi Jasra, MD, Mohammad Kazemi, Daniel Cole, Ana Acuna-Villaorduna, MD, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Olga Derman, MD, Noah Kornblum, MD, Ira Braunschweig, MD, Amit Verma, MD, Murali Janakiram, MD MS

Blood (2018) 132 (Supplement 1): 1713.

https://doi.org/10.1182/blood-2018-99-120143

Published: 2018

Journal Articles

Differentiating Lung Involvement in Adult T-Cell Leukemia Lymphoma (ATLL) Versus HTLV Infection: Results from a Large Single-Center Cohort with Implications for Staging and Response Criteria

Ana Acuna-Villaorduna, MD, Jesus D Gonzalez-Lugo, B. Hilda Ye, PhD, Urvi A Shah, MD, Gurbakhash Kaur, MDMA,BS, Nishi Shah, MBBS, MPH, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Ira Braunschweig, MD, Noah Kornblum, MD, Olga Derman, MD, Amit Verma, MD, Benjamin Zalta, MD, Murali Janakiram, MD MS

Blood (2018) 132 (Supplement 1): 1630.

https://doi.org/10.1182/blood-2018-99-119294

Published: 2018

Journal Articles

The Rising Number of Adult T Cell Leukemia Lymphoma (ATLL) Cases in Non-Hispanic Blacks and Its Association with Poor Outcomes

Urvi A Shah, MD, Nishi Shah, MBBS, MPH, Baozhen Qiao, PhD, Ana Acuna Villaorduna, MD, Aditi Shastri, MD, Ioannis Mantzaris, MD MS, Olga Derman, MD, Noah Kornblum, MD, Ira Braunschweig, MD, B. Hilda Ye, PhD, Amit Verma, MD, Murali Janakiram, MD

Blood (2018) 132 (Supplement 1): 1642.

https://doi.org/10.1182/blood-2018-99-111721

Published: 2018

Journal Articles

Phase 1/1b Study of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, As Monotherapy or in Combination with Cytarabine for the Treatment of Relapsed/Refractory AML and Advanced MDS with TP53 Wild-Type

David A Sallman, MD, Uma Borate, MD, Elizabeth H. Cull, MD, William B. Donnellan, MD, Rami S. Komrokji, MD, Ulrich G. Steidl, MD PhD, Maria M Corvez, Marie Payton, MBA, D. Allen Annis, PhD, Dawn Pinchasik, MD, Manuel Aivado, MD PhD, Amit Verma, MD

Blood (2018) 132 (Supplement 1): 4066.

https://doi.org/10.1182/blood-2018-99-118780

Published: 2018

Journal Articles

CHD1 - a Novel Epigenetic Regulator in Myeloid Malignancies with a Role in DNA Repair

Arpan Sinha, MBBS, MD, Adriana De La Garza, PhD, Amit Verma, MD, J. Kimble Frazer, MD PhD, Teresa V. Bowman, PhD

Blood (2018) 132 (Supplement 1): 2607.

https://doi.org/10.1182/blood-2018-99-114259

Published: 2018

Journal Articles

Reduced Expression of DOCK4 Leads to Increased Protein Phosphorylation and Migration of Hematopoietic Stem/Progenitor Cells

Sriram Sundaravel, MS, Wen Liang-Kuo, PhD, Hui Liu, MS, Jong Jeong, PhD, Gaurav Choudhary, PhD, Tushar Damodar Bhagat, PhD, Shanisha Gordon, Amit Verma, MD, Amittha Wickrema, PhD

Blood (2018) 132 (Supplement 1): 2563.

https://doi.org/10.1182/blood-2018-99-114320

Published: 2018

Journal Articles

Multiple Myeloma in Hispanics Is Associated with Better Survival Than Non-Hispanic African Americans and Whites: Analysis from a Large Single Center Minority Rich Cohort

Gurbakhash Kaur, MD MA, BS, Mateo Mejia Saldarriaga, MD, Ana Acuna-Villaorduna, MD, Mohammad Kazemi, Sakshi Jasra, MD, Nishi Shah, MBBS, MPH, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Olga Derman, MD, Noah Kornblum, MD, Ira Braunschweig, MD, Amit Verma, MD, Murali Janakiram, MD MS

Blood (2018) 132 (Supplement 1): 3601.

https://doi.org/10.1182/blood-2018-99-120282

Published: 2018

Journal Articles

Myelodysplastic Syndromes (MDS) Are an Independent Risk Factor for an Earlier Onset of Myocardial Infarction and Increased Mortality from Cardiovascular Disease (CVD)

Diego Adrianzen Herrera, MD, Kith Pradhan, PhD, Rosebella Snyder, MD, Siddharth Karanth, MBBS, MPH, DrPH, Murali Janakiram, MD MS, Ioannis Mantzaris, MD MS, Santosh Murthy, MD MPH, Amit Verma, MD, Aditi Shastri, MD

Blood (2018) 132 (Supplement 1): 3539.

https://doi.org/10.1182/blood-2018-99-115613

Published: 2018

Journal Articles

Plasma Cell Dyscrasias in HIV, Epidemiology, Presentation and Treatment Characteristics and Its Strong Association with Hepatitis C- Report Form a Large HIV Cohort

Nishi Shah, MBBS, MPH, Sakshi Jasra, MD, Ana Acuna-Villaorduna, MD, Urvi A Shah, MD, Gurbakhash Kaur, MD MA,BS, Mohammad Kazemi, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Olga Derman, MD, Noah Kornblum, MD, Ira Braunschweig, MD, Amit Verma, MD, Murali Janakiram, MD MS

Blood (2018) 132 (Supplement 1): 5607.

https://doi.org/10.1182/blood-2018-99-119222

Published: 2018

Journal Articles

PD-L1 Blockade with Atezolizumab in Higher-Risk Myelodysplastic Syndrome: An Initial Safety and Efficacy Analysis

Aaron T. Gerds, MDMS, Bart L Scott, MD, Peter L Greenberg, MD, Samer K. Khaled, MD, Tara L Lin, MD, Daniel A Pollyea, MD, Amit Verma, MD, Monique Dail, Cherie Green, Connie Ma, Bruno C Medeiros, Patrick Phuong, Michael Wenger, Mark Yan, William B. Donnellan, MD

Blood (2018) 132 (Supplement 1): 466.

https://doi.org/10.1182/blood-2018-99-118577

Published: 2018

Journal Articles

Iron Chelation Improves Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome

Wenbin An, MD, Maria Feola, PhD, Marc Ruiz Martinez, PhD, Amit Verma, MD, Yelena Ginzburg, MD

Blood (2018) 132 (Supplement 1): 2335.

https://doi.org/10.1182/blood-2018-99-119586

Published: 2018

Journal Articles

Autologous Transplantation Is Associated with Better Outcomes Compared to Chemotherapy Alone in a Minority-Rich Non-High-Risk Acute Myeloid Leukemia Cohort

Diego Adrianzen Herrera, MD, Nilupa Gaspe Mudiyanselage, MD, Pramod Gaudel, MD, Anjali Budhathoki, MD, Karine Darbinyan, MD, Aditi Shastri, MD, Murali Janakiram, MD, Adam F. Binder, MD, Noah Kornblum, MD, Olga Derman, Kira Gritsman, MD PhD, Ulrich G. Steidl, MDPhD, Amit Verma, MD, Ira Braunschweig, MD, Ioannis Mantzaris, MD

Blood (2017) 130 (Supplement 1): 3293.

https://doi.org/10.1182/blood.V130.Suppl_1.3293.3293

Published: 2017

Journal Articles

Obesity Is Associated with Younger Age at Presentation and More Severe Cytopenias in Myelodysplastic Syndromes

Santiago Thibaud, MD, Diego Adrianzen Herrera, MD, Rosebella Snyder, Justin D. Kaner, MD, Ioannis Mantzaris, MD, Swati Goel, MD, Amit Verma, MD, Aditi Shastri, MD

Blood (2017) 130 (Supplement 1): 5312.

https://doi.org/10.1182/blood.V130.Suppl_1.5312.5312

Published: 2017

Journal Articles

Direct Pharmacological Inhibition of the Transcription Factor PU.1 in Acute Myeloid Leukemia

Blood (2017) 130 (Supplement 1): 858.

https://doi.org/10.1182/blood.V130.Suppl_1.858.858

Published: 2017

Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD

Blood (2017) 130 (Supplement 1): 785.

https://doi.org/10.1182/blood.V130.Suppl_1.785.785

Published: 2017

Journal Articles

Dual Inhibition of Mdmx and Mdm2 Using an Alpha-Helical P53 Stapled Peptide (ALRN-6924) As a Novel Therapeutic Strategy in Acute Myeloid Leukemia

Luis A. Carvajal, PhD, Daniela Ben-Neriah, B.S, Adrien Senecal, PhD, Lumie Bernard, M.S, Swathi-Rao Narayanagari, M.S, Charles Kenworthy, B.S, Victor Thiruthuvanathan, M.S, Vincent Guerlavais, PhD, D. Allen Annis, PhD, Boris Bartholdy, PhD, Britta Will, PhD, Jesus Anampa, MD, Ioannis Mantzaris, MD, Manuel A. Aivado, MD PhD, Robert H Singer, PhD, Robert Coleman, PhD, Amit Verma, MD, Ulrich G. Steidl, MDPhD

Blood (2017) 130 (Supplement 1): 795.

https://doi.org/10.1182/blood.V130.Suppl_1.795.795

Published: 2017

Journal Articles

AML-Associated Somatic Mutations Can be Detected in Stem and Progenitor Populations in Patients with Antecedent Multiple Myeloma Years before Onset of Therapy-Related Transformation

Ashwin Sridharan, Carolina D. Schinke, MD, George Georgiev, Mariana Da Silva Ferreira, Kith Pradhan, PhD, Yu Xia, PhD, Maya Panjikaran, MS, Gregory Sims, Chirag Bhagat, Armin Graber, Christoph Heuck, MD, Daisy Alapat, MD, Niels Weinhold, PhD, Sarah K Johnson, PhD, Bart Barlogie, MD PhD, Gareth J. Morgan, MD PhD, Ulrich G. Steidl, MDPhD, Britta Will, PhD, Amit Verma, MD

Blood (2017) 130 (Supplement 1): 2706.

https://doi.org/10.1182/blood.V130.Suppl_1.2706.2706

Published: 2017

Journal Articles

Understanding Early Stage Myelodysplastic Syndrome Pathobiology

David Muench, BS, Amit Verma, MD, Lee Grimes

Blood (2017) 130 (Supplement 1): 2948.

https://doi.org/10.1182/blood.V130.Suppl_1.2948.2948

Published: 2017

Journal Articles

First Report of Reversible Macrocytic Anemia with Dysplastic Features Associated with Palbociclib Use in Patients with Metastatic Breast Cancer

Tamanna Haque, MD, Jesus Anampa, MD, Irina Murakhovskaya, MD, Yanhua Wang, MD PhD, Kimo Bachiashvili, MD, Cristian Papazoglu, MD PhD, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Amit Verma, MD

Blood (2017) 130 (Supplement 1): 2207.

https://doi.org/10.1182/blood.V130.Suppl_1.2207.2207

Published: 2017

NARROW

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

Causes and Predictors of Early Mortality in HIV-Positive and HIV-Negative Patients with Diffuse Large B-Cell Lymphoma

Differentiating Lung Involvement in Adult T-Cell Leukemia Lymphoma (ATLL) Versus HTLV Infection: Results from a Large Single-Center Cohort with Implications for Staging and Response Criteria

The Rising Number of Adult T Cell Leukemia Lymphoma (ATLL) Cases in Non-Hispanic Blacks and Its Association with Poor Outcomes

Phase 1/1b Study of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, As Monotherapy or in Combination with Cytarabine for the Treatment of Relapsed/Refractory AML and Advanced MDS with TP53 Wild-Type

CHD1 - a Novel Epigenetic Regulator in Myeloid Malignancies with a Role in DNA Repair

Reduced Expression of DOCK4 Leads to Increased Protein Phosphorylation and Migration of Hematopoietic Stem/Progenitor Cells

Multiple Myeloma in Hispanics Is Associated with Better Survival Than Non-Hispanic African Americans and Whites: Analysis from a Large Single Center Minority Rich Cohort

Myelodysplastic Syndromes (MDS) Are an Independent Risk Factor for an Earlier Onset of Myocardial Infarction and Increased Mortality from Cardiovascular Disease (CVD)

Plasma Cell Dyscrasias in HIV, Epidemiology, Presentation and Treatment Characteristics and Its Strong Association with Hepatitis C- Report Form a Large HIV Cohort

PD-L1 Blockade with Atezolizumab in Higher-Risk Myelodysplastic Syndrome: An Initial Safety and Efficacy Analysis

Iron Chelation Improves Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome

Autologous Transplantation Is Associated with Better Outcomes Compared to Chemotherapy Alone in a Minority-Rich Non-High-Risk Acute Myeloid Leukemia Cohort

Obesity Is Associated with Younger Age at Presentation and More Severe Cytopenias in Myelodysplastic Syndromes

Direct Pharmacological Inhibition of the Transcription Factor PU.1 in Acute Myeloid Leukemia

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Dual Inhibition of Mdmx and Mdm2 Using an Alpha-Helical P53 Stapled Peptide (ALRN-6924) As a Novel Therapeutic Strategy in Acute Myeloid Leukemia

AML-Associated Somatic Mutations Can be Detected in Stem and Progenitor Populations in Patients with Antecedent Multiple Myeloma Years before Onset of Therapy-Related Transformation

Understanding Early Stage Myelodysplastic Syndrome Pathobiology

First Report of Reversible Macrocytic Anemia with Dysplastic Features Associated with Palbociclib Use in Patients with Metastatic Breast Cancer

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American Society of Hematology

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American Society of Hematology

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