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Journal Articles

Human Adult Long-Term Repopulating Hematopoietic Stem Cells Can be Purified By Surface cMPL Expression

Daisuke Araki, Bryan Fisk, Christi Salisbury-Ruf, Neelam Redekar, Andre Larochelle

Blood (2023) 142 (Supplement 1): 1035.

https://doi.org/10.1182/blood-2023-179589

Published: 2023

Journal Articles

Granulocyte Colony-Stimulating Factor Impairs Engraftment of CRISPR-Cas9 Gene Edited Human Hematopoietic Stem Cells By Exacerbating p53 Mediated DNA Damage Response

Daisuke Araki, Vicky Chen, Neelam Redekar, Poching Li, Yan Luo, Yuesheng Li, Andre Larochelle

Blood (2022) 140 (Supplement 1): 307–308.

https://doi.org/10.1182/blood-2022-158511

Published: 2022

Journal Articles

Prospective Phase I/II Study of Eltrombopag for the Treatment of Bone Marrow Failure in Fanconi Anemia

Ma Evette Barranta, Fariba Chinian, Katherine Roskom, Tarik Lott, Julie Erb-Alvarez, Katherine R. Calvo, Thomas Winkler, Neelam Giri, Andre Larochelle

Blood (2021) 138 (Supplement 1): 2177.

https://doi.org/10.1182/blood-2021-148573

Published: 2021

Journal Articles

Diphtheria Toxin Based Bivalent Anti-cMPL Immunotoxin Effectively Depletes Human Hematopoietic Stem and Progenitor Cells

Daisuke Araki, Diogo M. Magnani, Zhirui Wang, Richard H. Smith, Andre Larochelle

Blood (2021) 138 (Supplement 1): 3808.

https://doi.org/10.1182/blood-2021-147392

Published: 2021

Journal Articles

Lentiviral Vector-Mediated Gene Transfer Restores CD18 Expression in Long-Term Repopulating Hematopoietic Stem and Progenitor Cells Isolated from a Patient with Leukocyte Adhesion Deficiency Type 1

Richard H. Smith, Daisuke Araki, Andre Larochelle

Blood (2021) 138 (Supplement 1): 1859.

https://doi.org/10.1182/blood-2021-148065

Published: 2021

Journal Articles

Gene Delivery Using Baculovirus in Human Hematopoietic Stem and Progenitor Cells Requires Inhibition of Cellular Innate Immune Pathways

Christi Salisbury-Ruf, Richard H. Smith, Fariba Chinian, Daisuke Araki, Keyvan Keyvanfar, Andre Larochelle

Blood (2021) 138 (Supplement 1): 2940.

https://doi.org/10.1182/blood-2021-148825

Published: 2021

Journal Articles

Administration of Granulocyte Colony-Stimulating Factor Post-Transplant Impedes Engraftment of CRISPR-Cas9 Edited Long-Term Repopulating Hematopoietic Stem and Progenitor Cells

Daisuke Araki, Christi Salisbury-Ruf, Waleed Hakami, Keyvan Keyvanfar, Richard H. Smith, Andre Larochelle

Blood (2021) 138 (Supplement 1): 2936.

https://doi.org/10.1182/blood-2021-147352

Published: 2021

Journal Articles

Notch-Mediated Expansion of Human Hematopoietic Stem and Progenitor Cells By Culture Under Hypoxia

Daisuke Araki, MD, Stefan Cordes, MD PhD, Fayaz Seifuddin, PhD, Luigi J. Alvarado, PhD, Mehdi Pirooznia, MD PhD, Richard H. Smith, PhD, Andre Larochelle, MD PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-141121

Published: 2020

Journal Articles

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

David J Young, MDPhD, Xing Fan, MD, Emma Groarke, MD, Bhavisha A Patel, MD, Ronan Desmond, MD, Thomas Winkler, MD, Andre Larochelle, MD PhD, Katherine R. Calvo, MD PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-141375

Published: 2020

Journal Articles

Phase II Study of Eltrombopag in Subjects with Fanconi Anemia

Daisuke Araki, MD, Ma Evette Barranta, Fariba Chinian, MS, Julie Erb-Alvarez, MPH, Thomas Winkler, MD, Neelam Giri, MD, Andre Larochelle, MD PhD

Blood (2019) 134 (Supplement_1): 3753.

https://doi.org/10.1182/blood-2019-123151

Published: 2019

Journal Articles

A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia

Blood (2019) 134 (Supplement_1): 2709.

https://doi.org/10.1182/blood-2019-122121

Published: 2019

Journal Articles

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Husam Qanash, MSc, Kaari Linask, Jeanette Beers, Keyvan Keyvanfar, Sara Young-Baird, Waleed Hakami, Richard H. Smith, Jizhong Zou, Andre Larochelle, MD PhD

Blood (2019) 134 (Supplement_1): 1214.

https://doi.org/10.1182/blood-2019-121822

Published: 2019

Journal Articles

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag

Thomas Winkler, Xing Fan, James Cooper, Ronan Desmond, David J. Young, Danielle M. Townsley, Phillip Scheinberg, Sophia Grasmeder, Andre Larochelle, Marie Desierto, Janet Valdez, Jennifer Lotter, Colin Wu, Ruba N. Shalhoub, Katherine R. Calvo, Neal S. Young, Cynthia E. Dunbar

Blood (2019) 133 (24): 2575–2585.

https://doi.org/10.1182/blood.2019000478

Published: 2019

Journal Articles

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

Luigi J. Alvarado, Heather D. Huntsman, Hai Cheng, Danielle M. Townsley, Thomas Winkler, Xingmin Feng, Cynthia E. Dunbar, Neal S. Young, Andre Larochelle

Blood (2019) 133 (19): 2043–2055.

https://doi.org/10.1182/blood-2018-11-884486

Published: 2019

Includes: Supplemental data

Journal Articles

Robust Cell Selections and Depletions across Various Hematopoietic Cell Fractions on the Clinimacs Plus Instrument

Thejaswi Bikkani, MBBS, Katherine Li, Anusha Rao, Angela Pickett, Xiaobai Li, PhD, Minoo Battiwalla, MD, Richard W. Childs, MD, John Barrett, MD, Andre Larochelle, MD PhD, Elizabeth Kang, MD, David F. Stroncek, Sandhya R. Panch, MD MPH

Blood (2018) 132 (Supplement 1): 3818.

https://doi.org/10.1182/blood-2018-99-118582

Published: 2018

Journal Articles

Generation of Fanconi Anemia iPSC Clones By Addition of a Small Molecule Inhibitor of p53 during Reprogramming

Husam Qanash, MSc, Kaari Linask, Jeannette Beers, Jizhong Zou, Andre Larochelle, MD PhD

Blood (2018) 132 (Supplement 1): 3857.

https://doi.org/10.1182/blood-2018-99-116896

Published: 2018

Journal Articles

Modulation of Mesodermal Patterning Combined with High VEGFA Concentrations Promote Robust Arterial Hemogenic Endothelium Differentiation from Human iPSCs

Juan Pablo Ruiz, BS, Andre Larochelle, MD PhD

Blood (2018) 132 (Supplement 1): 5093.

https://doi.org/10.1182/blood-2018-99-119332

Published: 2018

Journal Articles

Hypoxia and Notch Signaling Synergistically Expand Long-Term Repopulating Human Hematopoietic Stem/Progenitor Cells

Heather D. Huntsman, PhD, Daisuke Araki, MD, Richard H. Smith, PhD, Andre Larochelle, MD PhD

Blood (2018) 132 (Supplement 1): 2557.

https://doi.org/10.1182/blood-2018-99-119388

Published: 2018

Journal Articles

Heterodimerization of TPO and IFNγ Impairs Human Hematopoietic Stem/Progenitor Cell Signaling and Survival in Chronic Inflammation

Luigi J. Alvarado, PhD, Alessio Andreoni, PhD, Heather D. Huntsman, PhD, Hai Cheng, MD, Jay R. Knutson, PhD, Andre Larochelle, MD PhD

Blood (2017) 130 (Supplement 1): 4.

https://doi.org/10.1182/blood.V130.Suppl_1.4.4

Published: 2017

Journal Articles

Eltrombopag Promotes DNA Repair in Human Hematopoietic Stem and Progenitor Cells: Implications for the Treatment of Fanconi Anemia

Kacey Linnea Guenther, BS, Patali Shikhi Cheruku, BS, Richard H Smith, PhD, Andre Larochelle, MD PhD

Blood (2017) 130 (Supplement 1): 776.

https://doi.org/10.1182/blood.V130.Suppl_1.776.776

Published: 2017

NARROW

Human Adult Long-Term Repopulating Hematopoietic Stem Cells Can be Purified By Surface cMPL Expression

Granulocyte Colony-Stimulating Factor Impairs Engraftment of CRISPR-Cas9 Gene Edited Human Hematopoietic Stem Cells By Exacerbating p53 Mediated DNA Damage Response

Prospective Phase I/II Study of Eltrombopag for the Treatment of Bone Marrow Failure in Fanconi Anemia

Diphtheria Toxin Based Bivalent Anti-cMPL Immunotoxin Effectively Depletes Human Hematopoietic Stem and Progenitor Cells

Lentiviral Vector-Mediated Gene Transfer Restores CD18 Expression in Long-Term Repopulating Hematopoietic Stem and Progenitor Cells Isolated from a Patient with Leukocyte Adhesion Deficiency Type 1

Gene Delivery Using Baculovirus in Human Hematopoietic Stem and Progenitor Cells Requires Inhibition of Cellular Innate Immune Pathways

Administration of Granulocyte Colony-Stimulating Factor Post-Transplant Impedes Engraftment of CRISPR-Cas9 Edited Long-Term Repopulating Hematopoietic Stem and Progenitor Cells

Notch-Mediated Expansion of Human Hematopoietic Stem and Progenitor Cells By Culture Under Hypoxia

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

Phase II Study of Eltrombopag in Subjects with Fanconi Anemia

A Novel Proteomic Profiling of the Bone Marrow Microenvironment Reveals Elevated Levels of the Chemokine CCL23 Isoforms in Acute Myeloid Leukemia

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

Robust Cell Selections and Depletions across Various Hematopoietic Cell Fractions on the Clinimacs Plus Instrument

Generation of Fanconi Anemia iPSC Clones By Addition of a Small Molecule Inhibitor of p53 during Reprogramming

Modulation of Mesodermal Patterning Combined with High VEGFA Concentrations Promote Robust Arterial Hemogenic Endothelium Differentiation from Human iPSCs

Hypoxia and Notch Signaling Synergistically Expand Long-Term Repopulating Human Hematopoietic Stem/Progenitor Cells

Heterodimerization of TPO and IFNγ Impairs Human Hematopoietic Stem/Progenitor Cell Signaling and Survival in Chronic Inflammation

Eltrombopag Promotes DNA Repair in Human Hematopoietic Stem and Progenitor Cells: Implications for the Treatment of Fanconi Anemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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