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Journal Articles

ELANE Mutations in Cyclic and Congenital Neutropenia: Genotype-Phenotype Relationships,

David C. Dale, MD, Vahagn Makaryan, MD, Audrey Anna Bolyard, RN, BS, Elin R. Rodger, BS, RMT, Merideth L. Kelley, BS, Tracy M. Marrero, Lan Phan, BA, Andrew A Aprikyan, PhD, Mary Ann Bonilla, MD, Peter E. Newburger, MD, Laurence A. Boxer, MD, Daniel Link, MD

Blood (2011) 118 (21): 3398.

https://doi.org/10.1182/blood.V118.21.3398.3398

Published: 2011

Journal Articles

The Cellular and Molecular Mechanisms of Neutropenia in Barth Syndrome

Andrew A Aprikyan, PhD, Vahagn Makaryan, MD, Willem Kulik, PhD, Frederic Vaz, PhD, Christopher Allen, Yigal Dror, MD, David C. Dale, MD

Blood (2011) 118 (21): 1105.

https://doi.org/10.1182/blood.V118.21.1105.1105

Published: 2011

Journal Articles

Small Molecule Inhibitor of Neutrophil Elastase Normalizes Myeloid Differentiation and Improves Impaired Cell Survival Triggered by Elastase Mutations In Patients with Severe Congenital Neutropenia and Acute Myeloid Leukemia

Andrew A. Aprikyan, PhD, Vahagn Makaryan, MD, Maxim Totrov, PhD, Ruben Abagyan, PhD, David C. Dale, MD

Blood (2010) 116 (21): 386.

https://doi.org/10.1182/blood.V116.21.386.386

Published: 2010

Journal Articles

Mutant CXCR4-Induced Aberrant Retention and Apoptosis of Hematopoietic Cells in Myelokathexis and Normalization of Cell Survival and Mobilization with Specific Inhibitors.

Vahagn Makaryan, MD, Oscar Penate, MD, David C. Dale, MD, Andrew A Aprikyan, PhD

Blood (2009) 114 (22): 237.

https://doi.org/10.1182/blood.V114.22.237.237

Published: 2009

Journal Articles

Loss of Tafazzin (TAZ) Function and Accelerated Apoptosis of Human Bone Marrow Stem and Myeloid Progenitors in Barth Syndrome.

Vahagn Makaryan, MD, Yigal Dror, MD, Andrew A Aprikyan, PhD

Blood (2009) 114 (22): 549.

https://doi.org/10.1182/blood.V114.22.549.549

Published: 2009

Journal Articles

Small Molecule Inhibitor of Neutrophil Elastase and Severe Congenital Neutropenia.

Andrew A Aprikyan, PhD, Vahagn Makaryan, MD, Maxim Totrov, PhD, Ruben Abagyan, PhD, David C. Dale, MD

Blood (2009) 114 (22): 552.

https://doi.org/10.1182/blood.V114.22.552.552

Published: 2009

Journal Articles

Knock-Down of TAZ Gene Expression: A Model of Barth Syndrome with Accelerated Apoptosis of Myeloid Progenitor Cells Improved upon Treatment with Caspase-Specific Inhibitor

Vahagn Makaryan, MD, David C. Dale, MD, Andrew A Aprikyan, PhD

Blood (2008) 112 (11): 3558.

https://doi.org/10.1182/blood.V112.11.3558.3558

Published: 2008

Journal Articles

Dispensable Role of Neutrophil Elastase in Survival and Differentiation of Human Myeloid Progenitor Cells

Andrew A Aprikyan, PhD, Vahagn Makaryan, MD, Qian Si, PhD, Kelly Treonze, PhD, Nara Markosyan, Paul Finke, PhD, Salony Maniar, Richard Mumford, PhD, David C Dale, MD

Blood (2008) 112 (11): 3561.

https://doi.org/10.1182/blood.V112.11.3561.3561

Published: 2008

Journal Articles

Molecular Studies of Neutropenia in Barth Syndrome.

Andrew A. Aprikyan, PhD, Vahagn Makaryan, MD, David C. Dale, MD

Blood (2007) 110 (11): 3293.

https://doi.org/10.1182/blood.V110.11.3293.3293

Published: 2007

Journal Articles

Small Molecule Inhibitor of Neutrophil Elastase Restores Impaired Production of Human Myeloid Cells Observed in Severe Congenital Neutropenia.

Andrew A. Aprikyan, PhD, Vahagn Makaryan, MD, Qian Si, PhD, Kelly Treonze, PhD, Nara Markosyan, BS, Paul Finke, PhD, Maxim Totrov, PhD, Ruben Abagyan, PhD, Richard Mumford, BA, David Dale, MD

Blood (2007) 110 (11): 664.

https://doi.org/10.1182/blood.V110.11.664.664

Published: 2007

Journal Articles

A Model of Severe Congenital Neutropenia Reveals Signaling Pathways Mediating Mutant Elastase-Triggered Agranulocytosis.

Andrew A. Aprikyan, PhD, Tomas Vaisar, Vahagn Makaryan, MD, Jay Heinecke, MD

Blood (2005) 106 (11): 3070.

https://doi.org/10.1182/blood.V106.11.3070.3070

Published: 2005

Journal Articles

Mutant CXCR4 Identified in Neutropenic Patients with Myelokathexis Impairs Survival of Human Myeloid Cells.

Vahagn Makaryan, MD, David C. Dale, MD, Andrew A. Aprikyan, PhD

Blood (2005) 106 (11): 3071.

https://doi.org/10.1182/blood.V106.11.3071.3071

Published: 2005

NARROW

ELANE Mutations in Cyclic and Congenital Neutropenia: Genotype-Phenotype Relationships,

The Cellular and Molecular Mechanisms of Neutropenia in Barth Syndrome

Small Molecule Inhibitor of Neutrophil Elastase Normalizes Myeloid Differentiation and Improves Impaired Cell Survival Triggered by Elastase Mutations In Patients with Severe Congenital Neutropenia and Acute Myeloid Leukemia

Mutant CXCR4-Induced Aberrant Retention and Apoptosis of Hematopoietic Cells in Myelokathexis and Normalization of Cell Survival and Mobilization with Specific Inhibitors.

Loss of Tafazzin (TAZ) Function and Accelerated Apoptosis of Human Bone Marrow Stem and Myeloid Progenitors in Barth Syndrome.

Small Molecule Inhibitor of Neutrophil Elastase and Severe Congenital Neutropenia.

Knock-Down of TAZ Gene Expression: A Model of Barth Syndrome with Accelerated Apoptosis of Myeloid Progenitor Cells Improved upon Treatment with Caspase-Specific Inhibitor

Dispensable Role of Neutrophil Elastase in Survival and Differentiation of Human Myeloid Progenitor Cells

Molecular Studies of Neutropenia in Barth Syndrome.

Small Molecule Inhibitor of Neutrophil Elastase Restores Impaired Production of Human Myeloid Cells Observed in Severe Congenital Neutropenia.

A Model of Severe Congenital Neutropenia Reveals Signaling Pathways Mediating Mutant Elastase-Triggered Agranulocytosis.

Mutant CXCR4 Identified in Neutropenic Patients with Myelokathexis Impairs Survival of Human Myeloid Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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