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Anita Hill, MBChB, (Hons), PhD
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Journal Articles

Optimization of Dose Regimen for ALXN1210, a Novel Complement C5 Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results of 2 Phase 1/2 Studies

Alexander Roeth, MD, Scott T. Rottinghaus, MD, Anita Hill, MBChB (Hons), PhD, Jin Seok Kim, MD PhD, Hubert Schrezenmeier, MD, Louis Terriou, MD, Alvaro Urbano-Ispizua, MD, Richard A. Wells, MD DPhil, Jun Ho Jang, MD PhD, Jeff Szer, MB, BS, FRACP, Rasha Aguzzi, MS, Eric Scott Bachman, MD PhD, Andrew I. Damokosh, PhD, Lori Shafner, PhD, Jong-Wook Lee, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3482.
https://doi.org/10.1182/blood.V130.Suppl_1.3482.3482
Published: 2017
Journal Articles

Assessment of Eculizumab and C5 Levels in PNH Treatment: Molar Ratio of Eculizumab to C5 Level Effectively Predicts Ongoing Dosage Changes in a Cohort of 50 Patients Treated with Eculizumab

Darren J Newton, PhD, Claire E McKinley, BSc, Alonso Ricardo, PhD, Michelle D Hoarty, PhD, Louise Arnold, Kathryn Riley, Nicola Copeland, Talha Munir, Morag Griffin, Anita Hill, MBChB (Hons), PhD, Peter Hillmen, MBChB, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3484.
https://doi.org/10.1182/blood.V130.Suppl_1.3484.3484
Published: 2017
Journal Articles

Interim Analysis of Safety Outcomes during Treatment with Eculizumab: Results from the International Paroxysmal Nocturnal Hemoglobinuria Registry

Anita Hill, MBChB (Hons), PhD, Alexander Roeth, MD, Gérard Socié, MDPhD, Marie-Pierre Caby-Tosi, PharmD, PhD, Amanda Wilson, MPH, PhD, Philippe Gustovic, MD, Camille L. Bedrosian, MD, Robert A. Brodsky, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3486.
https://doi.org/10.1182/blood.V130.Suppl_1.3486.3486
Published: 2017
Journal Articles

Efficacy of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and High Disease Activity with or without History of Aplastic Anemia in the International PNH Registry

Jong-Wook Lee, MD, Regis Peffault De Latour, MD PhD, Robert A. Brodsky, MD, Jun Ho Jang, MD PhD, Anita Hill, MBChB (Hons), PhD, Alexander Roeth, MD, Hubert Schrezenmeier, MD, Amanda Wilson, MPH, PhD, Jing L. Marantz, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP
Journal: Blood
Blood (2017) 130 (Supplement 1): 3487.
https://doi.org/10.1182/blood.V130.Suppl_1.3487.3487
Published: 2017
Journal Articles

Extravascular Hemolysis Due to C3-Loading in Patients with PNH Treated with Eculizumab: Defining the Clinical Syndrome

Claire E McKinley, BSc, Stephen John Richards, PhD FRCPath, Talha Munir, Morag Griffin, Lindsay D Mitchell, MBChB, MRCP(UK), FRCPath, Louise Arnold, Kathryn Riley, Nicola Copeland, Darren J Newton, PhD, Anita Hill, MBChB (Hons), PhD, Peter Hillmen, MBChB, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3471.
https://doi.org/10.1182/blood.V130.Suppl_1.3471.3471
Published: 2017
Journal Articles

Thrombosis in Non-Hemolytic Paroxysmal Nocturnal Haemogloinuria

Morag Griffin, Talha Munir, Peter Hillmen, MBChB, PhD, Louise Arnold, Nicola Copeland, Kathryn Riley, Stephen John Richards, PhD FRCPath, Anita Hill, MBChB (Hons), PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1175.
https://doi.org/10.1182/blood.V130.Suppl_1.1175.1175
Published: 2017
Journal Articles

Fibrinogen and Clot Structure Is Affected By Eculizumab in Patients with Paroxysmal Nocturnal Haemoglobinuria

Fraser Macrae, BSc, PhD, Polly Bowman, Emma Linton, Barnaby Peacock-Young, Deborah Clarke, MSc, Darren J Newton, PhD, Claire E McKinley, BSc, Kathryn Riley, Nicola Copeland, Louise Arnold, Morag Griffin, Talha Munir, Peter Hillmen, MBChB, PhD, Stephen John Richards, PhD FRCPath, Robert Ariens, BSc, PhD, Anita Hill, MBChB (Hons), PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 462.
https://doi.org/10.1182/blood.V130.Suppl_1.462.462
Published: 2017
Journal Articles

Coversin, a Novel C5 Complement Inhibitor, Is Safe and Effective in the Treatment of PNH: Results of a Phase II Clinical Trial

Anita Hill, MBChB (Hons), PhD, Wynne Weston-Davies, MB FRCS, Miles Nunn, PhD, Tadeusz Robak, MD PhD, Jerzy Windyga, MD, Andrzej Hellmann, MD PhD DSc, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Agniezka Piekarska, Anna Szmigielska-Kaplon, Morag Griffin, Talha Munir
Journal: Blood
Blood (2017) 130 (Supplement 1): 4747.
https://doi.org/10.1182/blood.V130.Suppl_1.4747.4747
Published: 2017
Journal Articles

Effects of Eculizumab Therapy in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Receiving Concurrent Immunosuppressive Therapy for Bone Marrow Insufficiency.

Hubert Schrezenmeier, Joerg Schubert, MD, Lucio Luzzatto, MD, Petra Muus, MD, PhD, Gerard Socie, MD, PhD, Antonio M. Risitano, MD, PhD, Anita Hill, MBChB, (Hons), PhD, Peter Hillmen, MB, ChB, PhD
Journal: Blood
Blood (2009) 114 (22): 3012.
https://doi.org/10.1182/blood.V114.22.3012.3012
Published: 2009
Journal Articles

A Spontaneous Reduction of Clone Size in Paroxysmal Nocturnal Hemoglobinuria Patients Treated with Eculizumab for Greater Than 12 Months.

Richard Kelly, MBChB, Stephen Richards, PhD, Louise Arnold, BSc, MA, Gemma Valters, BSc, Matthew Cullen, MA, Anita Hill, MBChB, (Hons), PhD, Peter Hillmen, PhD
Journal: Blood
Blood (2009) 114 (22): 1992.
https://doi.org/10.1182/blood.V114.22.1992.1992
Published: 2009