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Journal Articles

Functional Overlap between the SEC23 Paralogs Suggests a Novel Treatment Paradigm for Congenital Dyserythropoietic Anemia Type II

Richard King, MD, Ann Friedman, BS, Zesen Lin, BS, Rami Khoriaty, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2221.
https://doi.org/10.1182/blood-2019-129669
Published: 2019
Journal Articles

Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease

Eric Perkey, BS, Léolène Carrington, PhD, Jooho Chung, MDPhD, David Granadier, BS, Alexander Dils, Ann Friedman, BS, Anastasia Tikhonova, PhD, Bruce R. Blazar, MD, Ute Koch, PhD, Nathalie Labrecque, PhD, Freddy Radtke, PhD, Chris Siebel, PhD BA, Iannis Aifantis, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 810.
https://doi.org/10.1182/blood-2018-99-110258
Published: 2018
Journal Articles

The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia

Nirmalya SAHA, PhD MSc, BSc, James Ropa, BS, Lili Chen, PhD, Hsiang-Yu Hu, BS, Maria Mysliwski, Ann Friedman, BS, Ivan Maillard, MD, Andrew G. Muntean, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1280.
https://doi.org/10.1182/blood-2018-99-118703
Published: 2018
Journal Articles

The Trithorax-Group Protein ASH1L Regulates Hematopoietic Stem Cell Homeostasis Independently of Its Histone Methyltransferase Activity

Gloria Jih, PhD, Jennifer Chase, PhD, Yile Zhou, MD PhD, Ann Friedman, BS, Xiaomin Feng, MD PhD, Manabu Nakayama, PhD, Haruhiko Koseki, PhD, Kenichi Nishioka, PhD, Gang Huang, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1270.
https://doi.org/10.1182/blood-2018-99-117367
Published: 2018
Journal Articles

Delta-like Ligands Expressed By Stromal Cells in Secondary Lymphoid Organs Deliver an Early Pulse of Notch Signaling and Drive T Cell Pathogenicity in Acute Graft-Versus-Host Disease

Jooho Chung, BS, Christen L. Ebens, MDMPH, Vedran Radojcic, MD, Ute Koch, PhD, Ann Friedman, BS, Ivy T. Tran, BS, Qian Chai, PhD, Lucas Onder, PhD, Minhong Yan, PhD, Pavan Reddy, MD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Christian W. Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD PhD
Journal: Blood
Blood (2014) 124 (21): 841.
https://doi.org/10.1182/blood.V124.21.841.841
Published: 2014
Journal Articles

Delta-Like Notch Ligands Expressed By Host Non-Hematopoietic Radioresistant Cells Regulate Graft-Versus-Host Disease and Extrathymic T Cell Development After Bone Marrow Transplantation

Christen L Ebens, MD, MPH, Jooho Chung, BS, Ute Koch, PhD, Ivy T Tran, BS, Ashley R Sandy-Sloat, PhD, Ann Friedman, BS, Bruce R Blazar, MD, Pavan Reddy, MD, Minhong Yan, PhD, Christian W Siebel, PhD, Freddy Radtke, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2003.
https://doi.org/10.1182/blood.V122.21.2003.2003
Published: 2013
Journal Articles

Notch Inhibition in Alloreactive CD4 + and CD8 + T Cells Blocks Graft-Versus-Host Disease by Inducing a Hyporesponsive Program with Features of T Cell Anergy

Ashley R Sandy, BS, Jooho Chung, BS, Ivy T Tran, BS, Gloria T Shan, BS, Ann Friedman, BS, Timothy S Blackwell, MD-PhD, Pavan Reddy, M.D., Philip D King, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 340.
https://doi.org/10.1182/blood.V120.21.340.340
Published: 2012
Journal Articles

The Trithorax Group Protein Ash1l Is An Essential Epigenetic Regulator of Adult Hematopoietic Stem Cell Maintenance

Morgan Jones, BS, MS, Michelle L Brinkmeier, PhD, Julien Schira, BS, MS, Ann Friedman, BS, Sami Malek, MD, Yali Dou, PhD, Sally A Camper, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 387.
https://doi.org/10.1182/blood.V118.21.387.387
Published: 2011
Journal Articles

In Vivo Blockade of Individual Notch Ligands and Receptors Provides a New Targeted Therapeutic Approach In Graft-Versus-Host Disease

Ivy T Tran, BS, Ashley R Sandy, BS, Alexis Carulli, BS, Gloria T Shan, BS, Vedran Radojcic, MD, Ann Friedman, BS, Amy Shelton, Linda C Samuelson, PhD, Minhong Yan, PhD, Christian W Siebel, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 819.
https://doi.org/10.1182/blood.V118.21.819.819
Published: 2011
Journal Articles

Hematopoietic Defects In ACD/TPP1-Deficient Mice Reveal An Essential Role for the Shelterin Complex In Blood-Forming Stem Cell Homeostasis

Morgan Jones, BS, MS, Gail A Osawa, BS, Ann Friedman, BS, Wylie Luo, Catherine E Keegan, MD, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 882.
https://doi.org/10.1182/blood.V116.21.882.882
Published: 2010
Journal Articles

Inhibition of Notch Signaling in T Cells Prevents Immune-Mediated Bone Marrow Failure.

Gloria T Shan, BS, Ivy Tran, Ashley R Sandy, BS, Ann Friedman, BS, Yi Zhang, MD, PhD, Ivan Maillard, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 180.
https://doi.org/10.1182/blood.V114.22.180.180
Published: 2009