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Journal Articles

Novel Evidence That Pituitary Gonadotropins Directly Stimulate Human Leukemic cells—studies on Myeloid Cell Lines and Primary Patient AML and CML Cells

Ahmed Ismail, PhD, Katarzyna Anna Mierzejewska, PhD, Anna Janowska-Wieczorek, MD PhD, A. Robert Turner, MD FRCPC, Mariusz Z Ratajczak, MD PhD, Magdalena Kucia, PhD

Blood (2014) 124 (21): 2204.

https://doi.org/10.1182/blood.V124.21.2204.2204

Published: 2014

Journal Articles

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Gabriela Schneider, Ph.D., Kim ChiHwa, PhD, Ahmed Abdel-Latif, MD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2012) 120 (21): 1247.

https://doi.org/10.1182/blood.V120.21.1247.1247

Published: 2012

Journal Articles

Studies in C4b-Deficient Mice Provide Further Evidence That Complement Cascade Orchestrates the Mobilization of Hematopoietic Stem/Progenitor Cells.

Anna Janowska-Wieczorek, MD, PhD, Leah A. Marquez-Curtis, PhD, Danila Leontyev, PhD, Donald R. Branch, PhD, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2012) 120 (21): 2316.

https://doi.org/10.1182/blood.V120.21.2316.2316

Published: 2012

Journal Articles

Mesenchymal Stem Cells Express the Surface Receptor Calreticulin (cC1qR) and Complement C1q Chemoattracts Them.

Yuanyuan Qiu, PhD, Leah A. Marquez-Curtis, PhD, Anna Janowska-Wieczorek, MD, PhD

Blood (2010) 116 (21): 3855.

https://doi.org/10.1182/blood.V116.21.3855.3855

Published: 2010

Journal Articles

MT1-MMP Associates with Membrane Lipid Rafts and Is Required for G-CSF-Induced Hematopoietic Stem/Progenitor Cell Mobilization.

Neeta Shirvaikar, MSc, Leah A. Marquez-Curtis, PhD, BSc, Andrew Shaw, PhD, A. Robert Turner, MD, FRCPC, Anna Janowska-Wieczorek, MD, PhD

Blood (2009) 114 (22): 3536.

https://doi.org/10.1182/blood.V114.22.3536.3536

Published: 2009

Journal Articles

Novel Mechanistic Insight Into Mobilization of Hematopoietic Stem/Progenitor Cells (HSPCs): Complement Cascade and Membrane Attack Complex Activated in Bone Marrow Sinusoids During Mobilization Release From Erythrocytes Sphingosine-1 Phosphate – An Underappreciated Chemoattractant Executing Egress of HSPCs.

HakMo Lee, PhD, Marcin Wysoczynski, PhD, Wan Wu, Rui Liu, M.D., Magdalena Kucia, Ph.D., Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, M.D., Ph.D., Mariusz Z Ratajczak, MD, PhD

Blood (2009) 114 (22): 31.

https://doi.org/10.1182/blood.V114.22.31.31

Published: 2009

Journal Articles

MMP-14 Mediates Migration of Acute Myelogenous Leukemia Cells

Neeta Shirvaikar, MSc, Ali Jalili, MSc, PhD, Imran Mirza, FRCPC, Sara Ilnitsky, BSc, Chris Korol, Loree M. Larratt, MD, A. Robert Turner, MD, FRCPC, Anna Janowska-Wieczorek, MD, PhD

Blood (2008) 112 (11): 2943.

https://doi.org/10.1182/blood.V112.11.2943.2943

Published: 2008

Journal Articles

The Role of C5a in the Mobilization of Hematopoietic Stem/Progenitor Cells

Ali Jalili, MSc, PhD, Neeta Shirvaikar, MSc, Chris Korol, Anna Janowska-Wieczorek, MD, PhD

Blood (2008) 112 (11): 3472.

https://doi.org/10.1182/blood.V112.11.3472.3472

Published: 2008

Journal Articles

The Potent Deacetylase Inhibitor Trichostatin a (TSA) Increases CXCR4 Expression in Hematopoietic Stem/Progenitor Cells by Chromatin Remodelling

Hilal Gul, PhD, MSc, Leah A. Marquez-Curtis, PhD, BSc, Jennifer Lo, Nadia Jahroudi, PhD, A. Robert Turner, MD, FRCPC, Loree M. Larratt, MD, Anna Janowska-Wieczorek, MD, PhD

Blood (2008) 112 (11): 3487.

https://doi.org/10.1182/blood.V112.11.3487.3487

Published: 2008

Journal Articles

CXCR7 Is Expressed in B Acute Lymphoblastic Leukemia (ALL) Cells and Mediates Their Transendothelial Migration.

Ali Jalili, PhD, MSc, Neeta Shirvaikar, MSc, Imran Mirza, FRCPC, Sara Ilnitsky, Mark Penfold, PhD, Thomas J Schall, PhD, Anna Janowska-Wieczorek, MD, PhD

Blood (2008) 112 (11): 1916.

https://doi.org/10.1182/blood.V112.11.1916.1916

Published: 2008

Journal Articles

G-CSF Induces Expression of Both Hepatocyte Growth Factor (HGF) and Its Receptor (c-Met) in Human Hematopoietic Stem/Progenitor Cells and Mature Myeloid Cells - Novel Evidence That during Mobilization the HGF-c-Met Axis Counterbalances G-CSF-Induced Attenuation of the SDF-1-CXCR4 Axis.

Ali Jalili, PhD, Neeta Shirvaikar, MSc, Sara Ilnitsky, BSc, A. Robert Turner, MD, Mariusz Z. Ratajczak, MD, PhD, Anna Janowska-Wieczorek, MD, PhD

Blood (2007) 110 (11): 2203.

https://doi.org/10.1182/blood.V110.11.2203.2203

Published: 2007

Journal Articles

Complement Cascade (CC) Cleavage Fragments - C3a and C5a Anaphylatoxins - As New Unexpected Hypoxia-Related Stimulators of Erythropoiesis.

Janina Ratajczak, MD, PhD, Marcin Wysoczynski, Bogdan Machalinski, MD, PhD, Anna Janowska-Wieczorek, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2007) 110 (11): 2220.

https://doi.org/10.1182/blood.V110.11.2220.2220

Published: 2007

Journal Articles

C1q Complement Cascade Protein as a Novel Modulator of the SDF-1-CXCR4 Axis and Hematopoietic Stem/Progenitor Cell Trafficking.

Ali Jalili, PhD, Neeta Shirvaikar, MSc, Mariusz Z. Ratajczak, MD, PhD, Anna Janowska-Wieczorek, MD, PhD

Blood (2007) 110 (11): 1212.

https://doi.org/10.1182/blood.V110.11.1212.1212

Published: 2007

Journal Articles

Histone Deacetylase Inhibitor Valproic Acid Has Differential Effects on Trafficking of Normal Hematopoietic Stem/Progenitor Cells and Leukemic Blasts.

Hilal Gul, PhD, Leah A. Marquez-Curtis, PhD, Ashraf Kharrat, Jencet Montano, BSc, A. Robert Turner, MD/PhD, Anna Janowska-Wieczorek, MD/PhD

Blood (2007) 110 (11): 1417.

https://doi.org/10.1182/blood.V110.11.1417.1417

Published: 2007

Journal Articles

Membrane Type-Matrix Metalloproteinases (MT-MMPs) Are Expressed in Acute Myeloid Leukemia Cells and Are Upregulated by TNF-α.

Neeta Shirvaikar, MSc, Ali Jalili, PhD, Sara Ilnitsky, BSc, Loree Larratt, MD, Imran Mirza, MD, Anna Janowska-Wieczorek, MD, PhD

Blood (2007) 110 (11): 2853.

https://doi.org/10.1182/blood.V110.11.2853.2853

Published: 2007

Journal Articles

An In Vitro and In Vivo Evidence That Downregulation of Leukemia Inhibitory Factor (LIF) Receptor (LIF-R) Decreases the Metastatic Potential of Human Rhabdomyosarcoma (RMS) Cells.

Marcin Wysoczynski, Katarzyna Miekus, Anna Marcinkowska, MD, Anna Janowska-Wieczorek, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2006) 108 (11): 2561.

https://doi.org/10.1182/blood.V108.11.2561.2561

Published: 2006

Journal Articles

Carboxypeptidase M Cleaves the C-Terminal Lysine of Stromal Cell-Derived Factor-1α and Is Expressed by Human Bone Marrow Cells.

Leah A. Marquez-Curtis, PhD, Kathleen Deiteren, MSc, Lambeir Anne-Marie, PhD, Ali Jalili, PhD, Neeta Shirvaikar, MSc, Anna Janowska-Wieczorek, MD, PhD

Blood (2006) 108 (11): 351.

https://doi.org/10.1182/blood.V108.11.351.351

Published: 2006

Journal Articles

A Novel Role for Thrombin in Hematopoietic Stem/Progenitor Cell Homing.

Neeta Shirvaikar, MSc, Ali Jalili, PhD, Mariusz Z. Ratajczak, MD,PhD, Anna Janowska-Wieczorek, MD,PhD

Blood (2006) 108 (11): 3374.

https://doi.org/10.1182/blood.V108.11.3374.3374

Published: 2006

Journal Articles

Mobilization Studies in Immunodeficient Mice Support a Role of Complement in Modulating the Trafficking of Hematopoietic Stem Cells (HSC) - A Pivotal Role of C3 Cleavage Fragments in Retention and C5 Fragments in Mobilization/Egress of HSC.

Ryan Reca, PhD, Marcin Wysoczynski, Kucia Magda, PhD, Anna Janowska-Wieczorek, MD, PhD, Janina Ratajczak, MD, PhD, Mariusz Z. Ratajczak, MD, PhD

Blood (2006) 108 (11): 3375.

https://doi.org/10.1182/blood.V108.11.3375.3375

Published: 2006

Journal Articles

Fibrinogen Enhances Homing-Related Responses of CD34 + by Incorporating Membrane Type1-Matrix Metalloproteinase into Membrane Lipid Rafts.

Neeta Shirvaikar, MSc, A. Robert Turner, MD, Mariusz Z. Ratajczak, MD,PhD, Anna Janowska-Wieczorek, MD,PhD

Blood (2006) 108 (11): 3188.

https://doi.org/10.1182/blood.V108.11.3188.3188

Published: 2006

NARROW

Novel Evidence That Pituitary Gonadotropins Directly Stimulate Human Leukemic cells—studies on Myeloid Cell Lines and Primary Patient AML and CML Cells

A Novel Perspective On Hematopoietic Stem/Progenitor Cell Homing - an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1

Studies in C4b-Deficient Mice Provide Further Evidence That Complement Cascade Orchestrates the Mobilization of Hematopoietic Stem/Progenitor Cells.

Mesenchymal Stem Cells Express the Surface Receptor Calreticulin (cC1qR) and Complement C1q Chemoattracts Them.

MT1-MMP Associates with Membrane Lipid Rafts and Is Required for G-CSF-Induced Hematopoietic Stem/Progenitor Cell Mobilization.

MMP-14 Mediates Migration of Acute Myelogenous Leukemia Cells

The Role of C5a in the Mobilization of Hematopoietic Stem/Progenitor Cells

The Potent Deacetylase Inhibitor Trichostatin a (TSA) Increases CXCR4 Expression in Hematopoietic Stem/Progenitor Cells by Chromatin Remodelling

CXCR7 Is Expressed in B Acute Lymphoblastic Leukemia (ALL) Cells and Mediates Their Transendothelial Migration.

G-CSF Induces Expression of Both Hepatocyte Growth Factor (HGF) and Its Receptor (c-Met) in Human Hematopoietic Stem/Progenitor Cells and Mature Myeloid Cells - Novel Evidence That during Mobilization the HGF-c-Met Axis Counterbalances G-CSF-Induced Attenuation of the SDF-1-CXCR4 Axis.

Complement Cascade (CC) Cleavage Fragments - C3a and C5a Anaphylatoxins - As New Unexpected Hypoxia-Related Stimulators of Erythropoiesis.

C1q Complement Cascade Protein as a Novel Modulator of the SDF-1-CXCR4 Axis and Hematopoietic Stem/Progenitor Cell Trafficking.

Histone Deacetylase Inhibitor Valproic Acid Has Differential Effects on Trafficking of Normal Hematopoietic Stem/Progenitor Cells and Leukemic Blasts.

Membrane Type-Matrix Metalloproteinases (MT-MMPs) Are Expressed in Acute Myeloid Leukemia Cells and Are Upregulated by TNF-α.

An In Vitro and In Vivo Evidence That Downregulation of Leukemia Inhibitory Factor (LIF) Receptor (LIF-R) Decreases the Metastatic Potential of Human Rhabdomyosarcoma (RMS) Cells.

Carboxypeptidase M Cleaves the C-Terminal Lysine of Stromal Cell-Derived Factor-1α and Is Expressed by Human Bone Marrow Cells.

A Novel Role for Thrombin in Hematopoietic Stem/Progenitor Cell Homing.

Mobilization Studies in Immunodeficient Mice Support a Role of Complement in Modulating the Trafficking of Hematopoietic Stem Cells (HSC) - A Pivotal Role of C3 Cleavage Fragments in Retention and C5 Fragments in Mobilization/Egress of HSC.

Fibrinogen Enhances Homing-Related Responses of CD34 + by Incorporating Membrane Type1-Matrix Metalloproteinase into Membrane Lipid Rafts.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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