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Journal Articles

Simultaneous Measurement of Thrombin Generation and Fibrin Formation in Whole Blood Applying Continuous Flow Is Predictive for the Amount of Blood Loss during/after Cardiothoracic Surgery

Leonie Pelkmans, Anne Bouwhuis, Evelien Schurgers, PhD, Theo Lindhout, PhD, Dana Huskens, PhD, Coenraad Hemker, PhD, Marcus Lancé, MD, Bas De Laat, PhD, Hilde Kelchtermans, PhD

Blood (2014) 124 (21): 2813.

https://doi.org/10.1182/blood.V124.21.2813.2813

Published: 2014

Journal Articles

Detecting Bleeding Risk in Patients Taking Vitamin K Antagonists Using Thrombin Generation Tests

Saartje Bloemen, Arina ten Cate-Hoek, Hugo ten Cate, Bas De Laat, PhD

Blood (2014) 124 (21): 2869.

https://doi.org/10.1182/blood.V124.21.2869.2869

Published: 2014

Journal Articles

Thrombin Generation in Zebrafish

Evelien Schurgers, PhD, Martijn Moorlag, Hilde Kelchtermans, PhD, Coenraad Hemker, PhD, Bas De Laat, PhD

Blood (2014) 124 (21): 4218.

https://doi.org/10.1182/blood.V124.21.4218.4218

Published: 2014

Journal Articles

Thrombin-Dependent Incorporation of Von Willebrand Factor into a Fibrin Network

Adam Miszta, PhD, Leonie Pelkmans, Theo Lindhout, PhD, Philip De Groot, Coenraad Hemker, PhD, Johan Heemskerk, PhD, Hilde Kelchtermans, PhD, Bas De Laat, PhD

Blood (2014) 124 (21): 101.

https://doi.org/10.1182/blood.V124.21.101.101

Published: 2014

Journal Articles

Increased Thrombin Generation and Fibrin Formation In Premature Aging BMAL1 Deficient Mice

Marisa Ninivaggi, Hilde Kelchtermans, PhD, Marijke Kuipers, PhD, Bianca Hemmeryckx, PhD, Johan Heemskerk, PhD, Theo Lindhout, PhD, Marc F. Hoylaerts, PhD, Bas De Laat, PhD

Blood (2013) 122 (21): 3575.

https://doi.org/10.1182/blood.V122.21.3575.3575

Published: 2013

Journal Articles

α2Macroglobulin Fails To Compensate For Decreased Thrombin Decay In Severe Antithrombin Deficiency In Liver Cirrhosis Patients

Romy Kremers, Marie-Claire Kleinegris, Bas De Laat, PhD, Rob Wagenvoord, PhD, Coenraad Hemker, PhD

Blood (2013) 122 (21): 3576.

https://doi.org/10.1182/blood.V122.21.3576.3576

Published: 2013

Journal Articles

Alpha-2-Macroglobulin Is a Major Determinant Of a Lower Thrombin Generation In Infants and Children Compared To Adults

Romy Kremers, Saartje Bloemen, Raed Al Dieri, PhD, Coen H Hemker, Vasiliki Karlaftis, Chantal Attard, Bas de Laat, PhD, Paul Monagle, MBBS, MD, MSc, Vera Ignjatovic, PhD

Blood (2013) 122 (21): 2344.

https://doi.org/10.1182/blood.V122.21.2344.2344

Published: 2013

Journal Articles

Thrombin Generation Measurement In Whole Blood As a Control For Vitamin K Antagonist Treatment - Effect Of Thrombomodulin

Saartje Bloemen, Marieke de Laat, Arina ten Cate-Hoek, Hugo ten Cate, Bas De Laat, PhD, H. Coenraad Hemker, PhD, Raed Al Dieri, PhD

Blood (2013) 122 (21): 3646.

https://doi.org/10.1182/blood.V122.21.3646.3646

Published: 2013

Journal Articles

The First Report Of Differences In Fibrin Clot Nanostructure and Response To Tissue Plasminogen Activator (TPA) and Unfractionated Heparin (UFH) In Infants Compared To Adults

Vera Ignjatovic, PhD, Leonie Pelkmans, Saartje Bloemen, Vasiliki Karlaftis, Chantal Attard, Raed Al Dieri, PhD, Bas de Laat, PhD, Paul Monagle, MBBS, MD, MSc

Blood (2013) 122 (21): 459.

https://doi.org/10.1182/blood.V122.21.459.459

Published: 2013

Journal Articles

Mechanism Of Peak Protraction In Thrombin Generation After Administration Of Direct Factor Xa Inhibitors

Saartje Bloemen, Bas De Laat, PhD, H. Coenraad Hemker, Raed Al Dieri, PhD

Blood (2013) 122 (21): 1141.

https://doi.org/10.1182/blood.V122.21.1141.1141

Published: 2013

Journal Articles

Binding of Erythrocyte ICAM–4 to the Platelet Activated Integrin α IIb β 3 leads to a Direct Erythrocyte-Platelet Adhesion Under Venous Flow Shear Rate

Vivian Xiaoyan Du, Philip G de Groot, PhD, Richard van Wijk, PhD, Zaverio M. Ruggeri, MD, PhD, Bas De Laat, PhD

Blood (2012) 120 (21): 105.

https://doi.org/10.1182/blood.V120.21.105.105

Published: 2012

Journal Articles

Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-β 2 -Glycoprotein I IgG Elisas Influences the Diagnosis of the Antiphospholipid Syndrome

Leonie Pelkmans, Hilde Kelchtermans, PhD, Marisa Ninivaggi, Theo Lindhout, PhD, Philip G de Groot, PhD, Vittorio Pengo, Bas De Laat, PhD

Blood (2012) 120 (21): 632.

https://doi.org/10.1182/blood.V120.21.632.632

Published: 2012

Journal Articles

Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.

Bas De Laat, PhD, Philip G. de Groot, PhD, Ronald H.W.M. Derksen, MD., Rolf T. Urbanus, Koen Mertens, PhD, Frits Rosendaal, MD, PhD, Carine J.M. Doggen, PhD

Blood (2008) 112 (11): 1813.

https://doi.org/10.1182/blood.V112.11.1813.1813

Published: 2008

Journal Articles

Antiphospholipid Antibodies with LAC Activity That Bind beta2-Glycoprotein I Cause Increased Resistance Against Activated Protein C.

Bas de Laat, PhD, Sander B. Meijer, PhD, Carel M. Eckmann, M. van Schagen, Koen Mertens, PhD, Jan A. van Mourik, PhD

Blood (2007) 110 (11): 3622.

https://doi.org/10.1182/blood.V110.11.3622.3622

Published: 2007

Journal Articles

Beta2-Glycoprotein I: Implications for a Regulatory Role in Thrombotic Thrombocytopenic Purpura.

Bas de Laat, PhD, Johanna A. Kremer Hovinga, MD, PhD, Wouter Pos, Evelyn Groot, Jing-Fei Dong, MD, PhD, Bernard Lammle, MD, PhD, Jan Voorberg, PhD, Philip G. de Groot, PhD

Blood (2007) 110 (11): 278.

https://doi.org/10.1182/blood.V110.11.278.278

Published: 2007

Journal Articles

Beta2-Glycoprotein I Interferes with von Willebrand Factor-Dependent Platelet Adhesion.

Peter J. Lenting, PhD, Janine J. Hulstein, PhD, Bas de Laat, PhD, Ronald H. Derksen, MD,PhD, Rob Fijnheer, MD,PhD, Philip G. de Groot, PhD

Blood (2006) 108 (11): 415.

https://doi.org/10.1182/blood.V108.11.415.415

Published: 2006

Journal Articles

Pathological Anti-β 2 -Glycoprotein I Antibodies Disrupt the Anticoagulant Activity of Annexin A5: A Possible Explanation for the Lupus Anticoagulant Paradox.

Bas de Laat, PhD, Xiao-Xuan Wu, PhD, Menno van Lummel, Ronald H.W.M. Derksen, PhD, MD, Philip G. de Groot, PhD, Jacob H. Rand, PhD

Blood (2005) 106 (11): 135.

https://doi.org/10.1182/blood.V106.11.135.135

Published: 2005

NARROW

Simultaneous Measurement of Thrombin Generation and Fibrin Formation in Whole Blood Applying Continuous Flow Is Predictive for the Amount of Blood Loss during/after Cardiothoracic Surgery

Detecting Bleeding Risk in Patients Taking Vitamin K Antagonists Using Thrombin Generation Tests

Thrombin Generation in Zebrafish

Thrombin-Dependent Incorporation of Von Willebrand Factor into a Fibrin Network

Increased Thrombin Generation and Fibrin Formation In Premature Aging BMAL1 Deficient Mice

α2Macroglobulin Fails To Compensate For Decreased Thrombin Decay In Severe Antithrombin Deficiency In Liver Cirrhosis Patients

Alpha-2-Macroglobulin Is a Major Determinant Of a Lower Thrombin Generation In Infants and Children Compared To Adults

Thrombin Generation Measurement In Whole Blood As a Control For Vitamin K Antagonist Treatment - Effect Of Thrombomodulin

The First Report Of Differences In Fibrin Clot Nanostructure and Response To Tissue Plasminogen Activator (TPA) and Unfractionated Heparin (UFH) In Infants Compared To Adults

Mechanism Of Peak Protraction In Thrombin Generation After Administration Of Direct Factor Xa Inhibitors

Binding of Erythrocyte ICAM–4 to the Platelet Activated Integrin α IIb β 3 leads to a Direct Erythrocyte-Platelet Adhesion Under Venous Flow Shear Rate

Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-β 2 -Glycoprotein I IgG Elisas Influences the Diagnosis of the Antiphospholipid Syndrome

Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.

Antiphospholipid Antibodies with LAC Activity That Bind beta2-Glycoprotein I Cause Increased Resistance Against Activated Protein C.

Beta2-Glycoprotein I: Implications for a Regulatory Role in Thrombotic Thrombocytopenic Purpura.

Beta2-Glycoprotein I Interferes with von Willebrand Factor-Dependent Platelet Adhesion.

Pathological Anti-β 2 -Glycoprotein I Antibodies Disrupt the Anticoagulant Activity of Annexin A5: A Possible Explanation for the Lupus Anticoagulant Paradox.

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American Society of Hematology

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American Society of Hematology

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