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Belinda Pinto Simões
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Journal Articles

An international learning collaborative phase 2 trial for haploidentical bone marrow transplant in sickle cell disease

CME Clinical Trials & Observations
Adetola A. Kassim, Josu de la Fuente, Erfan Nur, Karina L. Wilkerson, Ali D. Alahmari, Adriana Seber, Carmem Bonfim, Belinda Pinto Simões, Mohsen Alzahrani, Michael J. Eckrich, Biljana Horn, Rabi Hanna, Nathalie Dhedin, Hemalatha G. Rangarajan, Roseane Vasconcelos Gouveia, Fahad Almohareb, Mahmoud Aljurf, Mohammed Essa, Bader Alahmari, Katie Gatwood, James A. Connelly, Elisabeth Dovern, Mark Rodeghier, Michael R. DeBaun
Journal: Blood
Blood (2024) 143 (25): 2654–2665.
https://doi.org/10.1182/blood.2023023301
Published: 2024
Includes: Supplemental data
Journal Articles

Early Donor T-Cell Engraftment Is Critical for Immune Tolerance in Reduced Intensity Haploidentical Bone Marrow Transplant with Post-Transplant Cyclophosphamide for Sickle Cell Disease: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC 2 )

Jim A. Connelly, Eden Biltibo, Karina Wilkerson, Adriana Seber, Roseane V Gouveia, Carmem Bonfim, Belinda Pinto Simões, Erfan Nur, Biljana N. Horn, Michael Eckrich, Rabi Hanna, Nathalie Dhedin, Fahed Almhareb, Mahmoud Aljurf, Hemalatha G. Rangarajan, Katie S. Gatwood, Lindsay Orton, Carrie Lynn Kitko, Mohsen Alzahrani, Ali Debsan Alahmari, Josu De La Fuente, Adetola A. Kassim
Journal: Blood
Blood (2022) 140 (Supplement 1): 10462–10464.
https://doi.org/10.1182/blood-2022-170552
Published: 2022
Journal Articles

Outcomes of Non-Myeloablative HLA-Haploidentical Bone Marrow Transplant with Thiotepa and Post-Transplant Cyclophosphamide in Children and Adults with Sickle Cell Disease, a Phase II Trial: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC 2 )

Adetola A. Kassim, Karina Wilkerson, Josu de la Fuente, Adriana Seber, Roseane V Gouveia, Carmem Bonfim, Belinda Pinto Simões, Erfan Nur, Biljana N. Horn, Michael Eckrich, Rabi Hanna, Nathalie Dhedin, Fahed Almhareb, Mahmoud Aljurf, Hemalatha G. Rangarajan, Katie S. Gatwood, James P Connelly, Mohsen Alzahrani, Ali Alahmari, Mark Rodeghier, Michael R. DeBaun
Journal: Blood
Blood (2022) 140 (Supplement 1): 2383–2385.
https://doi.org/10.1182/blood-2022-165229
Published: 2022
Journal Articles

Outcomes of Non-Myeloablative HLA-Haploidentical Bone Marrow Transplant with Thiotepa and Post-Transplant Cyclophosphamide in Children and Adults with Severe Sickle Cell Disease, a Phase II Trial: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC 2 )

Adetola A. Kassim, MDMS, Josu de la Fuente, Ali Debsan Alahmari, MBBS, MD MNAMS, Michael J. Eckrich, MD MPH, Rabi Hanna, MD, Nathalie Dhedin, MD, Biljana N. Horn, MD, Vandy Black, MDMSc, Roseane V Gouveia, Adriana Seber, MDMS, Belinda Pinto Simões, MD PhD, Thalita Cristina de Mello Costa, MD, Renato Guerino-Cunha, Carmem M. S. Bonfim, MDPhD, Roberto Luiz da Silva, Nelson Hamerschlak, MD PhD, Juliana Folloni Fernandes, MD, Michael Kent, MDBS, Satya Prakash Yadav, MBBS, MD, Erfan Nur, MDPhD, Mohsen Alzahrani, Ben Carpenter, PhD, William Tse, MD, Maria Isabel, Hemalatha G Rangarajan, MD, Ibrahim Ahmed, MD, Adeseye Michael Akinsete, MBBS, Courtney D. Fitzhugh, MD, Kathryn A. Culos, PharmD, Leena Karnik, FRCPath, MRCP, James Connelly, MD, Carrie Kitko, MD, Jennifer Andrews, MDMSc, Karina L Wilkerson, NP, MSN, Robert Brodsky, Tatsuki Koyama, Michael R. DeBaun, MD MPH
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-141771
Published: 2020
Journal Articles

Human Leukocyte Antigen Matched Unrelated Donors for Patients with Sickle Cell Disease According to Geographic Origin: Results of International Donor Searches

Karina Tozatto-Maio, MD, Margareth Afonso Torres, MD, Neifi Hassan Saloum Degaide, PhD, Juliana Fernandes Cardoso, PhD, Fernanda Volt, MSc, Ana Cristina Silva Pinto, MD PhD, Danielli Oliveira, MD PhD, Hanadi Elayoubi, MD, Simone Kashima, PhD, Pascale Loiseau, Hendrik Veelken, MD PhD, Alina Ferster, MD, Barbara Cappelli, MD, Evandra Strazza Rodrigues, PhD, Graziana M. Scigliuolo, PharmD, Chantal Kenzey, Annalisa Ruggeri, MD, Vanderson Rocha, MD PhD, Renato Cunha, MD PhD, Belinda Pinto Simões, MD PhD, Ryad Tamouza, MD PhD, Eliane Gluckman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1021.
https://doi.org/10.1182/blood-2019-124592
Published: 2019
Journal Articles

Polymorphisms in Inflammatory Genes Modulate the Occurrence of Clinical Complications in Patients with Sickle Cell Disease

Karina Tozatto-Maio, MD, Robert Girot, MD PhD, Indou Deme Ly, MD, Vanderson Rocha, MD PhD, Ana Cristina Silva Pinto, MD PhD, Ibrahima Diagne, Prof, Yahia Benzerara, Francisco Fernandes, Carla Luana Dinardo, MD PhD, Simone Kashima, PhD, Itaua Leston Araujo, MSc, PhD, Chantal Kenzey, Guilherme Henrique Hencklain Fonseca, MD, Evandra Strazza Rodrigues, PhD, Fernanda Volt, MSc, Luciana Ribeiro Jarduli, PhD, Annalisa Ruggeri, MD, Christina Mary Mariaselvam, PhD, Sandra Fatima Menosi Gualandro, MD PhD, Hanadi Elayoubi, MD, Renato Cunha, MD PhD, Barbara Cappelli, MD, Julia Pavan, PhD, Belinda Pinto Simões, MD PhD, Eliane Gluckman, MD PhD, Ryad Tamouza, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4825.
https://doi.org/10.1182/blood-2019-124218
Published: 2019
Journal Articles

Experience of Generic Imatinib As a First Line Therapy for Patients with Chronic Myeloid Leukemia in a Single Reference Institution

Gabriel Carvalho Pereira, MD, Fernanda B da Silva, BSc and MSc, Luisa Espirito Santo Oliveira, Pedro Marques Garibaldi, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simões, MD PhD, Leonardo Carvalho Palma, MD PhD, Fabiola Traina, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5916.
https://doi.org/10.1182/blood-2019-132045
Published: 2019
Journal Articles

A Polymorphism in Toll-like Receptor 2 Gene Is Associated with Occurrence of Bacterial Infections in Sickle Cell Disease Patients

Karina Tozatto-Maio, MD, Robert Girot, MD, Indou Deme Ly, MD, Vanderson Rocha, MD PhD, Ana Cristina Silva Pinto, MD PhD, Ibrahima Diagne, Prof, Yahia Benzerara, Carla Luana Dinardo, MD PhD, Simone Kashima, PhD, Itaua Leston Araujo, MSc, Chantal Kenzey, Guilherme Henrique Hencklain Fonseca, MD, Evandra Rodrigues, PhD, Fernanda Volt, MSc, Luciana Ribeiro Jarduli, PhD, Annalisa Ruggeri, MD PhD, Christina Mary Mariaselvam, PhD, Sandra Fatima Menosi Gualandro, MD PhD, Hanadi Elayoubi, MD, Renato Cunha, MD PhD, Barbara Cappelli, MD, Belinda Pinto Simões, MD PhD, Eliane Gluckman, MD PhD, Ryad Tamouza, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3652.
https://doi.org/10.1182/blood-2018-99-112296
Published: 2018
Journal Articles

Alternative Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease in Europe

Barbara Cappelli, MD, Graziana Maria Scigliuolo, PharmD, Fernanda Volt, MSc, Selim Corbacioglu, MD, Josu de la Fuente, FRCP, PhD FRCPath, Nathalie Dhedin, MD, Corinne Pondarré, MD PhD, Juergen Foell, MD, Farah O' Boyle, PhD, Arjan Lankester, MD PhD, Elisabetta Calore, MD, Stefania Varotto, MD, Marco Zecca, MD, Amal Al-Seraihy, MD, Mahmoud Aljurf, MD, Anders Fasth, MD PhD, Sonia Bonanomi, MD, Maria Carmen Addari, MD, Franco Locatelli, Alina Ferster, MD, Veerle Labarque, PhD MD, Peter Bader, MD PhD, Belinda Pinto Simões, MD PhD, Karina Tozatto-Maio, MD, Vanderson Rocha, MD PhD, Mathieu Kuentz, MD, Hanadi Elayoubi, MD, Annalisa Ruggeri, MD, Francoise Bernaudin, MD, Eliane Gluckman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4645.
https://doi.org/10.1182/blood-2018-99-111129
Published: 2018
Journal Articles

Immune Profile of Sickle Cell Anemia Patients Treated with Allogeneic Stem Cell Transplantation

Julia Teixeira Cottas De Azevedo, MSc, Nathalia Ziegler de Oliveira, Keli Cristina de Lima, BSc, Thalita Cristina de Mello Costa, MD, Patrícia Vianna Bonini Palma, BSc, Dimas Tadeu Covas, MD PhD, Eduardo Donadi, Thiago Trovati Maciel, PhD, Olivier Hermine, MD PhD, Belinda Pinto Simões, MD PhD, Kelen Cristina Ribeiro Malmegrim, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5483.
https://doi.org/10.1182/blood.V130.Suppl_1.5483.5483
Published: 2017
Journal Articles

Recovery of Thymic Function after Allogeneic Hematopoietic Stem Cell Transplantation in with Sickle Cell Anemia Patients

Luciana Ribeiro Jarduli, BPharm, MMSc, Emmanuel Clave, PhD, Isabelle Fournier, Dimas Tadeu Covas, MD PhD, Ana Cristina Silva Pinto, MD PhD, Belinda Pinto Simões, MD PhD, Antoine Toubert, MD PhD, Kelen Cristina Ribeiro Malmegrim de Farias, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3261.
https://doi.org/10.1182/blood.V130.Suppl_1.3261.3261
Published: 2017
Journal Articles

Risk Factors and Outcomes According to Age at Transplant with an HLA Identical Sibling for Sickle Cell Disease

Barbara Cappelli, MD, Karina Tozatto-Maio, MD, Fernanda Volt, MSc, Annalisa Paviglianiti, MD, Alina Ferster, MD, Sophie Dupont, MD, Belinda Pinto Simões, MD PhD, Amal Al-Seraihy, MD, Mahmoud Aljurf, Cristina Belendez, MD, Susanne Matthes, MD, Nathalie Dhedin, MD, Jean-Hugues Dalle, MD PhD, Yves Bertrand, MD, Jean Pierre Vannier, MD, Mathieu Kuentz, MD, Patrick Lutz, MD, Gerard Michel, MD, Hanadi Elayoubi, MD, Benedicte Neven, MD, Josu de la Fuente, FRCP, PhD FRCPath, Marco Zecca, MD, Said Yousuf Ahmed, MD, Peter Bader, MD PhD, Annalisa Ruggeri, MD, Francoise Bernaudin, MD, Eliane Gluckman
Journal: Blood
Blood (2017) 130 (Supplement 1): 3317.
https://doi.org/10.1182/blood.V130.Suppl_1.3317.3317
Published: 2017
Journal Articles

Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation

CME Clinical Trials & Observations
Eliane Gluckman, Barbara Cappelli, Francoise Bernaudin, Myriam Labopin, Fernanda Volt, Jeanette Carreras, Belinda Pinto Simões, Alina Ferster, Sophie Dupont, Josu de la Fuente, Jean-Hugues Dalle, Marco Zecca, Mark C. Walters, Lakshmanan Krishnamurti, Monica Bhatia, Kathryn Leung, Gregory Yanik, Joanne Kurtzberg, Nathalie Dhedin, Mathieu Kuentz, Gerard Michel, Jane Apperley, Patrick Lutz, Bénédicte Neven, Yves Bertrand, Jean Pierre Vannier, Mouhab Ayas, Marina Cavazzana, Susanne Matthes-Martin, Vanderson Rocha, Hanadi Elayoubi, Chantal Kenzey, Peter Bader, Franco Locatelli, Annalisa Ruggeri, Mary Eapen
Journal: Blood
Blood (2017) 129 (11): 1548–1556.
https://doi.org/10.1182/blood-2016-10-745711
Published: 2017
Journal Articles

T Cell Repertoire Diversity of Sickle Cell Anemia Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Conventional Treatments

Luciana Ribeiro Jarduli, BPharm, MSc, PhD Student, Adriana Aparecida Marques, BS, Julia Teixeira Cottas de Azevedo, MSc, Keli Cristina de Lima, BS, Wilson Araújo da Silva Júnior, PhD, Dimas Tadeu Covas, MD, PhD, Belinda Pinto Simoes, MD, PhD, Ana Cristina Silva Pinto, MD, PhD, Kelen Cristina Ribeiro Malmegrim de Farias, BPharm, PhD
Journal: Blood
Blood (2016) 128 (22): 4586.
https://doi.org/10.1182/blood.V128.22.4586.4586
Published: 2016
Journal Articles

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

João Agostinho Machado-Neto, PhD, Bruna Alves Fenerich, B.Sc., Renata Scopim-Ribeiro, M.Sc., Carlos Roberto Porto Dechandt, B.Sc., Ana Paula Nunes Rodrigues Alves, M.Sc., Jaqueline Cristina Fernandes, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Luciane Carla Alberici, PhD, Lorena Lôbo de Figueiredo Pontes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 1960.
https://doi.org/10.1182/blood.V128.22.1960.1960
Published: 2016
Journal Articles

Pharmacological IGF1R/IRS Inhibitor, NT157, Effectively Induces Apoptosis and CDKN1A Expression in Acute Lymphoblastic Leukemia Cells

Ana Paula Nunes Rodrigues Alves, M.Sc., João Agostinho Machado-Neto, PhD, Jaqueline Cristina Fernandes, B.Sc., Bruna Alves Fenerich, B.Sc., Fernanda Borges da Silva, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3971.
https://doi.org/10.1182/blood.V128.22.3971.3971
Published: 2016
Journal Articles

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Paula de Melo Campos, PhD, Adriana da Silva Santos Duarte, PhD, Priscila Santos Scheucher, PhD, Amélia Góes, PhD, Sara Teresinha Olalla Saad, MD, PhD, Belinda Pinto Simoes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2772.
https://doi.org/10.1182/blood.V126.23.2772.2772
Published: 2015
Journal Articles

Hematopoietic Stem Cell Transplantation from HLA Identical Sibling Forsickle Cell Disease an International Survey on Behalf of Eurocord-Monacord, EBMT Paediatric Disease Working Party and CIBMTR

Barbara Cappelli, MD, Francoise Bernaudin, MD, Annalisa Ruggeri, MD PhD, Myriam Labopin, MD, Fernanda Volt, MT, Belinda Pinto Simoes, MD, PhD, Alina Ferster, MD PhD, Sophie Dupont, MD, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath, Jean-Hugues Dalle, MD PhD, Marco Zecca, MD, Marie Robin, MD PhD, Mark C. Walters, MD, Nathalie Dhedin, MD, Gerard Michel, MD, Patrick Lutz, Benedicte Neven, MD PhD, Yves Bertrand, MD PhD, Jean Pierre Vannier, MD PhD, Mouhab Ayas, MD, Susanne Matthes, MD, Hanadi Elayoubi, MD, Agnes Devergie, MD, Chantal Kenzey, CRA, Franco Locatelli, MD, Christina Peters, MD PhD, Vanderson Rocha, MD PhD, Mary Eapen, MBBS, Eliane Gluckman, MD
Journal: Blood
Blood (2015) 126 (23): 541.
https://doi.org/10.1182/blood.V126.23.541.541
Published: 2015
Journal Articles

The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival

Luisa C A Koury, Graduate Student, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simoes, MD, PhD, Luciana C O Oliveira, MD, Leandro F F Dalmazzo, MD, Maria Carolina Tostes Pintão, MD, Aglair B Garcia, Roberto Passetto Falcão, MD PhD, Eduardo Magalhães Rego, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 4896.
https://doi.org/10.1182/blood.V126.23.4896.4896
Published: 2015
Journal Articles

Association Analysis of Polymorphisms and Epistasis of Genes of IL-6, IL-10 and TNF-a in Patients with MM Submitted to ASCT

Fernanda M B Trigo, PharmD, Marcelo Luizon Rizzatti, PhD, Hélio Dutra, PhD, Maria Helena S Scaffo, Aguinaldo Luizon Simões, MD, PhD, Angelo Maiolino, MD, PhD, M. Nucci, MD, PhD, Belinda Pinto Simoes, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2026.
https://doi.org/10.1182/blood.V120.21.2026.2026
Published: 2012