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Betty S Pace, MD
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Journal Articles

Salubrinal Mediated Fetal Hemoglobin Induction through the eIF2α-ATF4 Signaling Pathway

Nicole Hope Lopez, BS, Biaoru Li, MDPhD, Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-139969
Published: 2020
Journal Articles

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Umapathy N Siddaramappa, PhD, Niren Patel, MBBS, Betty S. Pace, MD, Abdullah Kutlar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2258.
https://doi.org/10.1182/blood-2019-130924
Published: 2019
Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

David C Rees, Yurdanur Kilinc, MD, Selma Unal, Carlton Dampier, MD, Betty S. Pace, MD, Banu Kaya, MD, Sara Trompeter, MBChB BSc MRCPCH FRCPath MSc, Isaac Odame, Johnny N Mahlangu, MBBCH, MMed, FCPath, Sule Unal, MD, Julie Brent, MD, Regine Grosse, MD, Beng R. Fuh, MD, Baba PD Inusa, MD, Ariel Koren, MD, Carina Levin, MD PhD, Steven Mortier, Elizabeth McNamara, Yue Li, Stephen John Oliver, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 615.
https://doi.org/10.1182/blood-2019-123355
Published: 2019
Journal Articles

NRF2 Mediates Epigenetic Changes in DNA and Chromatin Structure to Regulate γ-Globin Gene Expression in a Human βYAC Transgenic Mouse Model

Xingguo Zhu, PhD, Alexander H. Ward, PhD, Caixia Xi, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1053.
https://doi.org/10.1182/blood-2018-99-116438
Published: 2018
Journal Articles

Novel Conjugates of Butyrate and δ-Aminolevulinate Increase γ-Globin Gene Expression and Fetal Hemoglobin Synthesis in Erythroid Progenitors

Aluya R. Oseghale, BSc, Marjorie M. Johnson, BS, Xingguo Zhu, PhD, Abraham Nudelman, PhD, Ada Rephaeli, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3511.
https://doi.org/10.1182/blood.V130.Suppl_1.3511.3511
Published: 2017
Journal Articles

Characterization of a HBB -Locus Fetal Chromatin Domain Region during Adult Erythropoiesis

Li Liu, PhD, Xingguo Zhu, PhD, Alexander Yu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2223.
https://doi.org/10.1182/blood.V130.Suppl_1.2223.2223
Published: 2017
Journal Articles

Salubrinal Mediated Fetal Hemoglobin Induction through the eIF2α-ATF4 Signaling Pathway

Nicole Hope Lopez, BS, Biaoru Li, MD PhD, Levi Makala, DVM, MBA, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2235.
https://doi.org/10.1182/blood.V130.Suppl_1.2235.2235
Published: 2017
Journal Articles

Loss of NRF2 Function Worsens the Pathophysiology of Sickle Cell Disease in a Transgenic Mouse Model

Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 960.
https://doi.org/10.1182/blood.V130.Suppl_1.960.960
Published: 2017
Journal Articles

Micro RNA Profiling to Identify Regulator of Fetal Hemoglobin Expression in Sickle Cell Disease

Biaoru Li, PhD, Christina M. Torres, BS, Mayuko Takezaki, MS, Cindy Neunert, MD MSCS, Abdullah Kutlar, MD, Betty S. Pace, MD
Journal: Blood
Blood (2014) 124 (21): 49.
https://doi.org/10.1182/blood.V124.21.49.49
Published: 2014
Journal Articles

A Cell-Based High-Throughput Screen For Novel Inducers Of Fetal Hemoglobin For Treatment Of Sickle Cell Disease, Cooley’s Anemia and β-Thalassemias

Kenneth R Peterson, PhD, Flavia C Costa, PhD, Halyna Fedosyuk, Renee Neades, Allen M Chazelle, Lesya Zelenchuk, Andrea H Fonteles, Parmita Dalal, Preston Donover, Melvin Reichman, PhD, Anuradha Roy, PhD, Rathnam Chaguturu, PhD, Li Biaoru, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2013) 122 (21): 925.
https://doi.org/10.1182/blood.V122.21.925.925
Published: 2013
Journal Articles

Monomethylfumarate (MMF), a Novel Inducer Of Fetal Hemoglobin In Human Erythroid Progenitors and Retinal Pigment Epithelial Cells

Levi Makala, PhD, DVM, Wanwisa Promsote, BS, Biaoru Li, PhD, Vadivel Ganapathy, PhD, Martin Pamela, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2013) 122 (21): 317.
https://doi.org/10.1182/blood.V122.21.317.317
Published: 2013
Journal Articles

Next Generation Clinical-Stage HbF Inducers Exhibit Multiple Molecular Actions In Vitro and In Vivo and Offer Personalized Therapeutic Regimens

Betty S. Pace, MD, Jose I Sangerman, PhD, Michael S Boosalis, PhD, Roman Wolf, DVM, Yan Dai, PhD, David H.K. Chui, MD, Levi Makala, PhD, DVM, Biadru Li, PhD, Douglas V Faller, MD, PhD, Susan P Perrine, MD
Journal: Blood
Blood (2013) 122 (21): 560.
https://doi.org/10.1182/blood.V122.21.560.560
Published: 2013
Journal Articles

Transcription Factor Networks Involved in Fetal Stem Cell Erythropoiesis

Biaoru Li, PhD/MD, Lianghao Ding, PhD, Chinrang Yang, PhD, Michael Story, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2012) 120 (21): 3444.
https://doi.org/10.1182/blood.V120.21.3444.3444
Published: 2012
Journal Articles

Resveratrol Regulates Fetal Hemoglobin Production by Inhibiting KLF1 and BCL11A in KU812 Cells

Davies G Agyekum, Zhong Chen, MD, Haiyan Xiao, Megan Yu, Niren Patel, MBBS, Betty S Pace, MD, Steffen E. Meiler, MD
Journal: Blood
Blood (2012) 120 (21): 1000.
https://doi.org/10.1182/blood.V120.21.1000.1000
Published: 2012
Journal Articles

Transcriptional Regulation of γ-Globin Gene Expression by KLF4

Inderdeep S Kalra, MS, Md. M Alam, BS, Betty S Pace, MD
Journal: Blood
Blood (2010) 116 (21): 645.
https://doi.org/10.1182/blood.V116.21.645.645
Published: 2010
Journal Articles

Human KU812 Erythroleukemia Cells: A Model for Competitive γ-Globin Induction by Fetal Hemoglobin Inducing Drugs.

Tzu-Fang Lou, MS, Shuguang Ma, Ashley Williams, Betty S. Pace, MD
Journal: Blood
Blood (2005) 106 (11): 2323.
https://doi.org/10.1182/blood.V106.11.2323.2323
Published: 2005
Journal Articles

Gene Expression Profiles Involved in γ to β Globin Gene Switching during Erythroid Maturation.

Wei Li, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2005) 106 (11): 820.
https://doi.org/10.1182/blood.V106.11.820.820
Published: 2005