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Bo Yu, Ph.D
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Journal Articles

Tumor Antigen ROR1 Targeted Delivery Of FTY720 Derivative OSU-2S Prolongs Survival In ROR1 Engineered Mouse Model Of Chronic Lymphocytic Leukemia

Rajeswaran Mani, DVM, Yicheng Mao, PhD, Frank W Frissora, M.S., Chi-ling Chiang, Jiang Wang, Yuan Zhao, Yun Wu, Bo Yu, Ph.D., Ribai Yan, Xiaokui Mo, PhD, Sivasubramanian Baskar, PhD, Christoph Rader, Ph.D., Mitch A. Phelps, PhD, Robert J. Lee, Ph.D, Ching-Shih Chen, PhD, James Lee, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, Ph.D
Journal: Blood
Blood (2013) 122 (21): 4168.
https://doi.org/10.1182/blood.V122.21.4168.4168
Published: 2013
Journal Articles

Protein Arginine Methyltransferase 5 (PRMT5) Over-Expression Is Essential for Epstein-Barr Virus-Driven B-Cell Transformation.

Lapo Alinari, MD., Ph.D., Fengting Yan, M.D., Ph.D., Porsha Smith, John T. Patton, Carl Quinion, Bo Yu, Ph.D, Christian Tyler Earl, Mark E Lustberg, MD, PhD, Lynda Villagomez, Erin K Hertlein, PhD, John C. Byrd, MD, Leona Ayers, MD, Tasneem Motiwala, PhD, Sarmila Majumder, PhD, Chenglong Li, Ph.D., Said Sif, Ph.D., Samson T. Jacob, PhD, Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2378.
https://doi.org/10.1182/blood.V120.21.2378.2378
Published: 2012
Journal Articles

Therapeutic Targeting of the RAS-Pathway by Synthetic Mir-181a Nanoparticles in Acute Myeloid Leukemia (AML).

Xiaomeng Huang, Sebastian Schwind, MD, Ann-Kathrin Eisfeld, MD, Bo Yu, Ph.D, Ramasamy Santhanam, Ph.D, Pia Hoellerbauer, Yan Jin, Ph.D, Christopher Hickey, Ph.D, Jiuxia Pang, Kenneth K. Chan, Ph.D, Danilo Perrotti, MD, Ph.D, Natarajan Muthusamy, DVM, Ph.D, John C. Byrd, MD, William Blum, MD, Clara D. Bloomfield, MD, Shujun Liu, Ph.D, Ramiro Garzon, MD, Robert J. Lee, Ph.D, L. James Lee, Ph.D, Guido Marcucci, MD
Journal: Blood
Blood (2012) 120 (21): 2422.
https://doi.org/10.1182/blood.V120.21.2422.2422
Published: 2012
Journal Articles

Targeted Delivery of MicroRNA-29b by Nanoparticles Provides Antileukemic Activity and Increases Sensitivity to the Hypomethylating Agent Decitabine (DAC) in Acute Myeloid Leukemia (AML)

Xiaomeng Huang, Sebastian Schwind, MD, Bo Yu, Ph.D, Jiuxia Pang, Ramasamy Santhanam, Ph.D, Kenneth K. Chan, Ph.D, Ramiro Garzon, MD, William Blum, MD, Clara D. Bloomfield, MD, Shujun Liu, Ph.D, Danilo Perrotti, MD, Ph.D, Robert J. Lee, Ph.D, John C. Byrd, MD, Natarajan Muthusamy, DVM, Ph.D, L. James Lee, Ph.D, Guido Marcucci, MD
Journal: Blood
Blood (2011) 118 (21): 81.
https://doi.org/10.1182/blood.V118.21.81.81
Published: 2011
Journal Articles

Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma

Fengting Yan, M.D., Ph.D., Porsha Smith, Lapo Alinari, MD., Ph.D., John Ryu, Bo Yu, Ph.D., Vrajesh Karkhanis, Ph.D., Sookil Tae, Ph.D., John T. Patton, Emily E. Wilding, Kate Gordon, Kiran Mahasenan, Ph.D., Deepak Bhasin, Ph.D., Claudio Agostinelli, M.D., Ph.D., Stefano A. Pileri, M.D., John C. Byrd, MD, Said Sif, Ph.D., Pui-kai Li, Ph.D., Chenglong Li, Ph.D., Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 595.
https://doi.org/10.1182/blood.V118.21.595.595
Published: 2011
Journal Articles

FTY720 Increases CD74 Expression and Sensitizes Mantle Cell Lymphoma Cells to Milatuzumab-Mediated Cell Death

Lapo Alinari, MD., Ph.D., Emilia Mahoney, MD, PhD, John T. Patton, Xiaoli Zhang, PhD, MS, Lenguyen Huynh, Christian Tyler Earl, Rajeswaran Mani, DVM, Yicheng Mao, Bo Yu, Ph.D., William H. Towns, Ching-Shih Chen, Ph.D, David M. Goldenberg, Kristie A. Blum, MD, John C. Byrd, MD, Natarajan Muthusamy, DVM, Ph.D, Mette Ibba, PhD, Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 600.
https://doi.org/10.1182/blood.V118.21.600.600
Published: 2011