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Journal Articles

Rock Inhibitor Fasudil Reduces Leukocyte-Endothelium Interactions in the Microvasculature of a Sickle Cell Mouse Model of Allergic Inflammation

Athos Rodrigues Moraes, Hanan Chweih, BSc, Nicola Conran, PhD, Kleber Yotsumoto Fertrin, MD PhD, Fernando Ferreira Costa, MD PhD, Carla Fernanda Franco-Penteado, BSc, PhD

Blood (2017) 130 (Supplement 1): 961.

https://doi.org/10.1182/blood.V130.Suppl_1.961.961

Published: 2017

Journal Articles

Red Blood Cells Microparticles Are Associated with Hemolysis Markers and Leg Ulceration in Patients with Sickle Cell Disease

Oladele Olatunya, MD, Carolina Lanaro, PhD, Ana Leda Figueiredo Longhini, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Sara Teresinha Olalla Saad, MD PhD, Kleber Yotsumoto Fertrin, MD PhD, Adekunle Adekile, MBBS, PhD FMCPaed, FWACP, FRCPCH, FRCP, Fernando Ferreira Costa, MD PhD

Blood (2017) 130 (Supplement 1): 3510.

https://doi.org/10.1182/blood.V130.Suppl_1.3510.3510

Published: 2017

Journal Articles

Intravascular Hemolysis Leads to Increased Esophagus Smooth Muscle Contractions in Mice: Implication for Dysphagia and Odynophagia

Fabio H Silva, PhD, Eduardo C Alexandre, PhD, Fabiano B Calmasini, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Edson Antunes, PhD, Kleber Yotsumoto Fertrin, MD PhD, Fernando Ferreira Costa, MD PhD

Blood (2017) 130 (Supplement 1): 3470.

https://doi.org/10.1182/blood.V130.Suppl_1.3470.3470

Published: 2017

Journal Articles

Increased Inflammatory Properties of Neutrophils in Patients with Venous Thromboembolism and the Effect of Simvastatin on Abrogating Inflamed Neutrophils Adhesiveness

Kiara Cristina Senger Zapponi, MSc, Fernanda Andrade Orsi, MD PhD, Ingrid Rafaela de Brito, Laboratory technician, Anna Virginia Calazans Romano, MSc, José Luiz Rosenberis Cunha Junior, MSc, Silmara Aparecida De Lima Montalvão, MSc, Fernanda Dutra Santiago Bassora, PhD, Luis Fernando Bittar, PhD, Erich Vinicius De Paula, Sr., MD PhD, Carla Fernanda Franco Penteado, PhD, Joyce Maria Annichino-Bizzacchi, MD PhD

Blood (2016) 128 (22): 3681.

https://doi.org/10.1182/blood.V128.22.3681.3681

Published: 2016

Journal Articles

Oxidative Stress Contributes to Overactive Bladder in the Transgenic Sickle Cell Mouse

Fabio Henrique Silva, M.Sc, PhD, Celso Saragosa Ramos Filho, PhD, Fabiano Beraldi Calmasini, M.Sc, Eduardo Costa Alexandre, M.Sc, Roger Barbosa Ferreira, Mariana Goncalves de Oliveira, M.Sc, Mário Angelo Claudino, BSc, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Edson Antunes, PhD, Fernando F Costa, MD, PhD

Blood (2015) 126 (23): 4582.

https://doi.org/10.1182/blood.V126.23.4582.4582

Published: 2015

Journal Articles

miRNA-146a, miRNA-203a, and miRNA-223 Modulate Inflammatory Response in LPS- Acute Lung Injury in Sickle Cell Transgenic Mice

Roger Barbosa Ferreira, Regiane Ferreira, MSc, BSc, Dulcineia Martins Albuquerque, PhD, Fernando F Costa, PhD MD, Carla Fernanda Franco-Penteado, BSc, PhD

Blood (2015) 126 (23): 3390.

https://doi.org/10.1182/blood.V126.23.3390.3390

Published: 2015

Journal Articles

Townes Transgenic Sickle Cell Mouse Model Displays Erectile Dysfunction

Fábio Henrique Silva, BSc, MSc, PhD, Mário Angelo Claudino, BSc, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Edson Antunes, BSc, MSc, PhD, Fernando Ferreira Costa, MD PhD

Blood (2014) 124 (21): 1376.

https://doi.org/10.1182/blood.V124.21.1376.1376

Published: 2014

Journal Articles

High Transferrin Saturation Is Associated with Lower Monocytic Ferritin Heavy Chain Expression in Sickle Cell Anemia Patients

Kleber Yotsumoto Fertrin, MD PhD, Carolina Lanaro, BSc, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Dulcinéia Martins Albuquerque, BSc, MSc, PhD, Betania Lucena Hatzlhofer, BSc, MSc, Mariana Rezende Bandeira Mello, BSc, MSc, PhD, Marcos André Cavalcanti Bezerra, PhD, Aderson da Silva Araujo, MD PhD, Fernando Ferreira Costa, MD PhD

Blood (2014) 124 (21): 4058.

https://doi.org/10.1182/blood.V124.21.4058.4058

Published: 2014

Journal Articles

Inhibition Of the Rho/Rho-Kinase Pathway Reduces In Vitro Adhesion Of Sickle Cell Anemia Eosinophils To Human Endothelial Cells

Flavia Rubia Pallis, BSc, MSc, Daiana Morelli Vital, B.Sc., Kleber Yotsumoto Fertrin, MD, PhD, Sara T O Saad, MD, PhD, Nicola Conran, PhD, Fernando Ferreira Costa, MD, PhD, Carla Fernanda Franco-Penteado, PhD

Blood (2013) 122 (21): 2219.

https://doi.org/10.1182/blood.V122.21.2219.2219

Published: 2013

Journal Articles

Rho-Kinase Inhibition Attenuates Airway Inflammation In An Experimental Asthma Model In Sickle Cell Mice

Flavia Rubia Pallis, BSc, MSc, Camila Bononi Almeida, Ph.D., Marcus Corat, PhD, Carolina Lanaro, BSc, PhD, Nicola Conran, PhD, Fernando Ferreira Costa, MD, PhD, Carla Fernanda Franco-Penteado, PhD

Blood (2013) 122 (21): 731.

https://doi.org/10.1182/blood.V122.21.731.731

Published: 2013

Journal Articles

Hydroxyurea Therapy Reduces The Hypercoagulability State In a Sickle Cell Mouse Model

Marina Pereira Colella, MD, Camila Bononi Almeida, Ph.D., Nicola Conran, PhD, Flavia Rubia Pallis, BSc, MSc, Carla Fernanda Franco-Penteado, Ph.D, Joyce Maria Annichino-Bizzacchi, MD, PhD, Fernando Ferreira Costa, MD, PhD, Erich Vinicius de Paula, MD, PhD, Sara Terezinha Olalla-Saad, M.D., Ph.D., Fabiola Traina, MD, PhD

Blood (2013) 122 (21): 2234.

https://doi.org/10.1182/blood.V122.21.2234.2234

Published: 2013

Journal Articles

Young and Old Sickle Cell Disease Transgenic Mice Present Underactive Bladder

Mário Angelo Claudino, B.Sc., Ph.D, Luiz Osório Leiria, Ph.D., Carla Fernanda Franco-Penteado, PhD, Fabio Henrique Silva, M.Sc, Marcus Corat, PhD, Edson Antunes, BSc, MSc, Ph.D, Fernando Ferreira Costa, MD, PhD

Blood (2013) 122 (21): 2248.

https://doi.org/10.1182/blood.V122.21.2248.2248

Published: 2013

Journal Articles

Monocyte Shift to a Non-Classical CD14 dim /CD16 + Phenotype Correlates with Fetal Hemoglobin Levels in Sickle Cell Anemia Patients Treated with Hydroxyurea

Kleber Yotsumoto Fertrin, MD, PhD, Dulcinéia Martins Albuquerque, BSc, MSc, PhD, Carolina Lanaro, BSc, PhD, Carla Fernanda Franco-Penteado, PhD, Flavia Rubia Pallis, BSc, MSc, Sara T. Olalla Saad, MD, PhD, Fernando Ferreira Costa, MD, PhD

Blood (2012) 120 (21): 817.

https://doi.org/10.1182/blood.V120.21.817.817

Published: 2012

Journal Articles

Hepcidin Production in Ineffective Erythropoiesis and Chronic Hemolysis: Insights on the Crosstalk Between Erythropoiesis and Iron Metabolism

Kleber Yotsumoto Fertrin, MD, Carolina Lanaro, B.Sc., Ph, D, Carla Fernanda Franco-Penteado, PhD, Dulcinéia Martins Albuquerque, BSc, MSc, PhD, Mariana Rezende Bandeira Mello, BSc, MSc, PhD, Marcos André Cavalcanti Bezerra, MSc, PhD, Betania Lucena Borges Tavares Domingues, BSc, Gordana Olbina, PhD, Sara T. Olalla Saad, MD, PhD, Aderson S Araujo, MD, PhD, Mark Westerman, PhD, Fernando Ferreira Costa, MD, PhD

Blood (2011) 118 (21): 346.

https://doi.org/10.1182/blood.V118.21.346.346

Published: 2011

Journal Articles

Lapdesf 1 a Compound Hybrid of Hydroxyrea and Thalidomide Increases Gamma Globin Expression in the Human CD34 + Cultures and Reduces Chemotactic Activity in Neutrophils

Sheley Gambero, B.Sc., M.Sc, Carolina Lanaro, B.Sc., Ph, D, Flavia Rubia Pallis, B.Sc., Carla Fernanda Franco-Penteado, PhD, Lidia Moreira Lima, B.Sc., M.Sc., Ph, D, Jean Leandro Santos, Chung Man Chin, B.Sc., M.Sc., Ph, D, Fernando Ferreira Costa, MD, PhD

Blood (2011) 118 (21): 2124.

https://doi.org/10.1182/blood.V118.21.2124.2124

Published: 2011

Journal Articles

Hydroxyurea Induces Hepcidin Expression In Monocytes In Sickle Cell Anemia Patients

Kleber Yotsumoto Fertrin, M.D., Carolina Lanaro, B.Sc., Ph.D., Carla Fernanda Franco-Penteado, B.Sc., M.Sc., Ph, D., Dulcinéia Martins Albuquerque, B.Sc., M.Sc., Ph.D., Mariana R. B. Mello, B.Sc., M.Sc., Marcos André Cavalcanti Bezerra, M.Sc., Ph.D., Betania Lucena Borges Tavares Domingues, B.Sc., Sara T. Olalla-Saad, M.D., Ph.D., Aderson S. Araujo, M.D., Ph.D., Fernando Ferreira Costa, M.D., Ph.D.

Blood (2010) 116 (21): 2653.

https://doi.org/10.1182/blood.V116.21.2653.2653

Published: 2010

Journal Articles

Altered Functional Properties of Eosinophils In Sickle Cell Anemia and Effects of Hydroxyurea Therapy

Flavia Rubia Pallis, B.Sc., Nicola Conran, PhD, Kleber Yotsumoto Fertrin, MD, Sara T. Olalla-Saad, M.D., Ph.D., Fernando Ferreira Costa, Ph.D., M.D., Carla Fernanda Franco-Penteado, PhD

Blood (2010) 116 (21): 2656.

https://doi.org/10.1182/blood.V116.21.2656.2656

Published: 2010

Journal Articles

Upregulation of the Anti-Apoptotic Protein, Survivin, in Hematopoietic Cells in Sickle Cell Anemia and Effects of Hydroxyurea Therapy.

Carolina Lanaro, B.Sc., Ph.D, Carla Fernanda Franco-Penteado, B.Sc., M.Sc., Ph.D, Mariana R. B. Mello, B.Sc., M.Sc, Kleber Yotsumoto Fertrin, MD, Marcos André C Bezerra, Ph.D., Dulcinéia M. Albuquerque, B.Sc., M.Sc., Ph.D, Nicola Conran, Ph.D., Sara T.O. Saad, MD, PhD, Aderson S. Araujo, M.D., Ph.D., Fernando F. Costa, PhD, MD

Blood (2009) 114 (22): 1532.

https://doi.org/10.1182/blood.V114.22.1532.1532

Published: 2009

Journal Articles

Reduction of Urinary Bladder Activity in Transgenic Sickle Cell Disease Mice.

Mário Angelo Claudino, B.Sc., Ph.D, Carla Fernanda Franco-Penteado, B.Sc., M.Sc., Ph.D, Marcus A.F. Corat, B.Sc., M.Sc., Ph.D, Ana Paula Gimenes, B.Sc, Kleber Yotsumoto Fertrin, MD, Luiz Augusto C Passos, B.Sc., M.Sc., Ph.D, Edson Antunes, B.Sc., M.Sc., Ph.D, Fernando Ferreira Costa, Ph.D., M.D.

Blood (2009) 114 (22): 2580.

https://doi.org/10.1182/blood.V114.22.2580.2580

Published: 2009

Journal Articles

Effect of High Levels of Growth Differentiation Factor 15 (GDF15) On Hepcidin Expression in Monocytes of β-Thalassemia Intermedia Patients.

Kleber Yotsumoto Fertrin, MD, Carolina Lanaro, B.Sc., Ph.D, Carla Fernanda Franco-Penteado, B.Sc., M.Sc., Ph.D, Dulcinéia M Albuquerque, B.Sc., M.Sc.,Ph.D, Mariana R. B. Mello, B.Sc., M.Sc, Marcos André C Bezerra, Ph.D., Betania Lucena Borges Tavares Domingues, B.Sc, Sara T.O Saad, M.D., Ph.D., Aderson S Araujo, M.D., Ph.D., Fernando Ferreira Costa, Ph.D., M.D.

Blood (2009) 114 (22): 4061.

https://doi.org/10.1182/blood.V114.22.4061.4061

Published: 2009

NARROW

Rock Inhibitor Fasudil Reduces Leukocyte-Endothelium Interactions in the Microvasculature of a Sickle Cell Mouse Model of Allergic Inflammation

Red Blood Cells Microparticles Are Associated with Hemolysis Markers and Leg Ulceration in Patients with Sickle Cell Disease

Intravascular Hemolysis Leads to Increased Esophagus Smooth Muscle Contractions in Mice: Implication for Dysphagia and Odynophagia

Increased Inflammatory Properties of Neutrophils in Patients with Venous Thromboembolism and the Effect of Simvastatin on Abrogating Inflamed Neutrophils Adhesiveness

Oxidative Stress Contributes to Overactive Bladder in the Transgenic Sickle Cell Mouse

miRNA-146a, miRNA-203a, and miRNA-223 Modulate Inflammatory Response in LPS- Acute Lung Injury in Sickle Cell Transgenic Mice

Townes Transgenic Sickle Cell Mouse Model Displays Erectile Dysfunction

High Transferrin Saturation Is Associated with Lower Monocytic Ferritin Heavy Chain Expression in Sickle Cell Anemia Patients

Inhibition Of the Rho/Rho-Kinase Pathway Reduces In Vitro Adhesion Of Sickle Cell Anemia Eosinophils To Human Endothelial Cells

Rho-Kinase Inhibition Attenuates Airway Inflammation In An Experimental Asthma Model In Sickle Cell Mice

Hydroxyurea Therapy Reduces The Hypercoagulability State In a Sickle Cell Mouse Model

Young and Old Sickle Cell Disease Transgenic Mice Present Underactive Bladder

Monocyte Shift to a Non-Classical CD14 dim /CD16 + Phenotype Correlates with Fetal Hemoglobin Levels in Sickle Cell Anemia Patients Treated with Hydroxyurea

Hepcidin Production in Ineffective Erythropoiesis and Chronic Hemolysis: Insights on the Crosstalk Between Erythropoiesis and Iron Metabolism

Lapdesf 1 a Compound Hybrid of Hydroxyrea and Thalidomide Increases Gamma Globin Expression in the Human CD34 + Cultures and Reduces Chemotactic Activity in Neutrophils

Hydroxyurea Induces Hepcidin Expression In Monocytes In Sickle Cell Anemia Patients

Altered Functional Properties of Eosinophils In Sickle Cell Anemia and Effects of Hydroxyurea Therapy

Upregulation of the Anti-Apoptotic Protein, Survivin, in Hematopoietic Cells in Sickle Cell Anemia and Effects of Hydroxyurea Therapy.

Reduction of Urinary Bladder Activity in Transgenic Sickle Cell Disease Mice.

Effect of High Levels of Growth Differentiation Factor 15 (GDF15) On Hepcidin Expression in Monocytes of β-Thalassemia Intermedia Patients.

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