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Cheng Liu, PhD
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Journal Articles

A TCR Mimic Antibody-Directed CAR T Cell Specific for Intracellular NDC80 Is Broadly Cancer Reactive and Displays High Activity Against Hematological Malignancies

Martin G. Klatt, MD, Zhiyuan Yang, PhD, Jianying Liu, PhD, Tatyana Korontsvit, MD, Sung Soo Mun, Leila Peraro, PhD, Thomas J. Gardner, PhD, Christopher Bourne, Megan M. Dacek, Tao Dao, MD PhD, Cheng Liu, PhD, David A. Scheinberg, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-140179
Published: 2020
Journal Articles

CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma

Eric L. Smith, MD PhD, Kimberly Harrington, Mette Staehr, PhD, Reed Masakayan, MS, Jon Jones, BS, Thomas Long, PhD, Majid Ghoddusi, DVM, PhD, Terence J Purdon, MS, Trevor Do, Xiuyan Wang, PhD, Minh Pham, Jessica M Brown, Elizabeth Peguero, Carlos Fernández De Larrea, MD PhD, Pei Wang, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Sarah Garrett, Steven Almo, PhD, Isabelle Riviere, PhD, Cheng Liu, PhD, Blythe Duke Sather, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 589.
https://doi.org/10.1182/blood-2018-99-110471
Published: 2018
Journal Articles

ET190L1-Artemis TM T Cell Therapy Results in Durable Disease Remissions with No Cytokine Release Syndrome or Neurotoxicity in Patients with Relapsed and Refractory B-Cell Lymphoma

Zhitao Ying, MD PhD, Li Long, MD PhD, Hong Liu, MD PhD, Yuqin Song, MD PhD, David A. Rizzieri, MD, Bijan Nejadnik, MD, Jun Zhu, MD PhD, Cheng Liu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1689.
https://doi.org/10.1182/blood-2018-99-113163
Published: 2018
Journal Articles

Development of JCARH125: Optimization of a Fully Human Anti-Bcma CAR for Use in the Treatment of Multiple Myeloma

Kim Harrington, BS, Rebecca Wu, BS, Collin Hauskins, BS, Rupesh Amin, PhD, Thomas Long, PhD, Aye Chen, BA, Ayu Rahardjo, BS, Casey Thayer, BS, Garnet Navvaro, BS, Madelyn Myers, MS, Jon Jones, BS, Alex Baturevych, BS, Stan Morkowski, PhD, Ruth Salmon, PhD, Christopher J Bond, PhD, Mette Staehr, PhD, Terence J Purdon, MS, Reed Masakayan, MS, Cheng Liu, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Pei Wang, PhD, Margot Pont, PhD, Damian J. Green, MD, Renier J. Brentjens, MD PhD, Eric L Smith, MDPhD, Blythe Duke Sather, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1813.
https://doi.org/10.1182/blood.V130.Suppl_1.1813.1813
Published: 2017
Journal Articles

Development and Evaluation of a Human Single Chain Variable Fragment (scFv) Derived Bcma Targeted CAR T Cell Vector Leads to a High Objective Response Rate in Patients with Advanced MM

Eric L Smith, MDPhD, Sham Mailankody, MBBS, Arnab Ghosh, MBBS, PhD, Reed Masakayan, MS, Mette Staehr, PhD, Terence J Purdon, MS, Elizabeth Halton, NP, Claudia Diamonte, RN, Pavan Anant, Yvette Bernal, MS, Xiuyan Wang, PhD, Yongzeng Wang, PhD, Sarah Garrett, Steven Almo, PhD, Pei Wang, PhD, Hong Liu, MD PhD, Yiyang Xu, PhD, Elena Mead, MD, Jae H. Park, MD, Kevin J. Curran, MD, Craig S. Sauter, MD, Sergio A. Giralt, MD, Ola Landgren, MD PhD, Ahmet Dogan, MD PhD, Mikhail Roshal, MDPhD, Cheng Liu, PhD, Isabelle Riviere, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 742.
https://doi.org/10.1182/blood.V130.Suppl_1.742.742
Published: 2017
Journal Articles

Enhancing CAR T Cell Anti-Tumor Efficacy through Secreted Single Chain Variable Fragment (scFv) Immune Checkpoint Blockade

Sarwish Rafiq, PhD, Hollie J. Jackson, PhD, Oladapo Yeku, MD PhD, Terence J Purdon, MS, Dayenne G. van Leeuwen, Kevin J. Curran, MD, Ryan N Ahmed, Grace D Cullen, Su Yan, Pei Wang, PhD, Jingyi Xiang, Cheng Liu, PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 842.
https://doi.org/10.1182/blood.V130.Suppl_1.842.842
Published: 2017
Journal Articles

CD47 Blockade Enhances Therapeutic Activity of TCR Mimic Antibodies to Ultra-Low Density Cancer Epitopes through Cytokine Feed Forward Mechanisms

Melissa D Mathias, MD, Jonathan T Sockolosky, PhD, Aaron Yu-Yuan Chang, BS, Cheng Liu, PhD, K. Christopher Garcia, PhD, David A. Scheinberg, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4048.
https://doi.org/10.1182/blood.V128.22.4048.4048
Published: 2016
Journal Articles

Anti-CD19 ARTEMIS TM Therapy Drastically Reduces Cytokine Release without Compromising Efficacy Against Preclinical Lymphoma Models

Hong Liu, PhD, Li Long, MD PhD, Shon Green, PhD, Lucas H Horan, PhD, Bryan Zimdahl, PhD, Cheng Liu, PhD
Journal: Blood
Blood (2016) 128 (22): 3354.
https://doi.org/10.1182/blood.V128.22.3354.3354
Published: 2016
Journal Articles

A Therapeutic TCR Mimic Monoclonal Antibody for Intracellular PRAME Protein in Leukemias

Aaron Chang, Tao Dao, PhD, Andrew Scott, Leonid Dubrovsky, MD, Cheng Liu, PhD, David A. Scheinberg, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2527.
https://doi.org/10.1182/blood.V126.23.2527.2527
Published: 2015
Journal Articles

Engineered T Cell Receptor-Mimic Antibody, (TCRm) Chimeric Antigen Receptor (CAR) T Cells Against the Intracellular Protein Wilms Tumor-1 (WT1) for Treatment of Hematologic and Solid Cancers

Sarwish Rafiq, PhD, Tao Dao, MDPhD, Cheng Liu, PhD, David A. Scheinberg, MD PhD, Renier J Brentjens, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2155.
https://doi.org/10.1182/blood.V124.21.2155.2155
Published: 2014
Journal Articles

A Bi-Specific T Cell Engaging Monoclonal Antibody (mAb) Derived From a TCR-Like Mab Specific For WT1/HLA-A0201 (ESK-BiTE) Shows a Potent Activity Against Human AML and Ph+ ALL In Mouse Models

Dmitry Pankov, MD, Tao Dao, MD, PhD, Yiyang Wang, Andrew Scott, Tatyana Korontsvit, MD, Victoria Zakhaleva, Nicholas Veomett, Michael Curcio, Ekaterina Doubrovina, MD, PhD, Richard J. O'Reilly, MD, Cheng Liu, PhD, David A. Scheinberg, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2521.
https://doi.org/10.1182/blood.V122.21.2521.2521
Published: 2013
Journal Articles

Therapeutic Efficacy and Cure Of Sensitive and T315I Pan-Resistant Human Ph+ Leukemia In Mice Using a TCR-Like Antibody To WT1/HLA-A0201 Alone, Or In Combination With Tyrosine Kinase Inhibitors

Leonid Dubrovsky, MD, Elliott Brea, Dmitry Pankov, MD, Nicholas Veomett, Tao Dao, MD/PhD, Su Yan, PhD, Cheng Liu, PhD, David A. Scheinberg, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 855.
https://doi.org/10.1182/blood.V122.21.855.855
Published: 2013
Journal Articles

Native and Fc Enhanced Therapeutic Human Monoclonal Antibodies Targeting the Intracellular WT1 Oncogene Product in Leukemia.

Nicholas Veomett, Tao Dao, MD, PhD, Dmitry Pankov, MD, Su Yan, PhD, Richard J. O'Reilly, MD, Cheng Liu, PhD, David A. Scheinberg, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2599.
https://doi.org/10.1182/blood.V120.21.2599.2599
Published: 2012
Journal Articles

A Cytotoxic Human Monoclonal Antibody Recognizing Cell Surface WT1 Peptide/HLA-A2 Complexes

David A. Scheinberg, MD, PhD, Tao Dao, MD, PhD, Su Yan, PhD, Liang Zhou, PhD, Tatyana Korontsvit, Victoriya Zakhaleva, Michael Curcio, Cheng Liu, PhD
Journal: Blood
Blood (2011) 118 (21): 1677.
https://doi.org/10.1182/blood.V118.21.1677.1677
Published: 2011