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Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-136064

Published: 2020

Journal Articles

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-142314

Published: 2020

Journal Articles

A Double Blind Randomised Clinical Trial to Prevent Serious Side Effects of Dexamethasone during Pediatric Acute Lymphoblastic Leukemia Treatment

Lidewij T Warris, MD, Marry M van den Heuvel-Eibrink, MD PhD, Femke K Aarsen, MSc PhD, Saskia MF Pluijm, Marc B Bierings, MDPhD, Cor van den Bos, MDPhD, Christian M. Zwaan, MD PhD, Wim JE Tissing, MD PhD, Margreet A Veening, MD, Rob Pieters, MD PhD, Erica LT van den Akker, MDPhD

Blood (2015) 126 (23): 2495.

https://doi.org/10.1182/blood.V126.23.2495.2495

Published: 2015

Journal Articles

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Blood (2015) 126 (23): 1244.

https://doi.org/10.1182/blood.V126.23.1244.1244

Published: 2015

Journal Articles

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

Sebastiaan D.T. Sassen, PharmD, Ron A.A. Mathôt, PharmD, PhD, Rob Pieters, MD PhD, Valerie de Haas, MD PhD, Gertjan JL Kaspers, MD PhD, Cor van den Bos, MDPhD, Wim JE Tissing, MD PhD, Maroeska D.W.M. te Loo, MD PhD, Marc B Bierings, MDPhD, Wouter J.W. Kollen, MD PhD, Christian M. Zwaan, MD PhD, Inge M. van der Sluis, MD PhD

Blood (2015) 126 (23): 1281.

https://doi.org/10.1182/blood.V126.23.1281.1281

Published: 2015

Journal Articles

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Christian M. Zwaan, MD PhD, Michael Dworzak, MD PhD, Thomas Klingebiel, MD, Claudia Rössig, MD, Guy Leverger, MD, Jan Stary, Evelina S. de Bont, MDPhD, Satianand Ramnarain, MSc, Yves Bertrand, MD, Benoit Brethon, MD, Brigitte Strahm, MD, Gertjan J. Kaspers, MD PhD, Dirk Reinhardt, MD PhD

Blood (2014) 124 (21): 989.

https://doi.org/10.1182/blood.V124.21.989.989

Published: 2014

Journal Articles

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

Edwin Sonneveld, PhD, Christian M. Zwaan, MD, PhD, Alita J van der Sluijs-Gelling, Valerie de Haas, MD, PhD, Rob Pieters, Vincent H.J. van der Velden, PhD

Blood (2013) 122 (21): 4950.

https://doi.org/10.1182/blood.V122.21.4950.4950

Published: 2013

Journal Articles

Molecular Aberrations in 107 Children with Myelodysplastic Syndrome (MDS).

Blood (2012) 120 (21): 2802.

https://doi.org/10.1182/blood.V120.21.2802.2802

Published: 2012

Journal Articles

Glucocorticoid-Induced Proliferation and Differentiation of Untreated Pediatric AML Cells

Eric Haarman, MD, PhD, Jacqueline Cloos, PhD, Christian M. Zwaan, MD, PhD, Valerie de Haas, MD, PhD, Dirk Reinhardt, MD, PhD, Ursula Creutzig, MD, PhD, Gertjan J. Kaspers, MD, PhD

Blood (2011) 118 (21): 4873.

https://doi.org/10.1182/blood.V118.21.4873.4873

Published: 2011

Journal Articles

IER3 Expression in Childhood Myelodysplastic Syndrome,

Andrica de Vries, MD, Christian M. Zwaan, MD, PhD, Astrid Danen- van Oorschot, PhD, Valerie de Haas, Henrik Hasle, M.D., Franco Locatelli, Prof, MD, PhD, Barbara De Moerloose, M.D., Sophia Polychronopoulou, MD, Jan Stary, M.D., Markus Schmugge, M.D., Michael Dworzak, M.D., Marco Zecca, M.D., H. Berna Beverloo, PhD, Charlotte M Niemeyer, Rob Pieters, MD, PhD, Marry M. van den Heuvel, MD, PhD

Blood (2011) 118 (21): 3817.

https://doi.org/10.1182/blood.V118.21.3817.3817

Published: 2011

Journal Articles

Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group,

Blood (2011) 118 (21): 3579.

https://doi.org/10.1182/blood.V118.21.3579.3579

Published: 2011

Journal Articles

Germline Mitochondrial DNA Mutations As a Novel First Event in Childhood Myelodysplastic Syndrome

Andrica de Vries, MD, Christian M. Zwaan, MD, PhD, H. Berna Beverloo, PhD, Anja Wagner, PhD, Arjan Lankester, MD, PhD, Peter te Boekhorst, MD, PhD, Rene de Coo, MD, PhD, Kees Schoonderwoerd, PhD, Bert Smeets, PhD, Sophia Polychronopoulou, MD, Rob Pieters, MD, PhD, Marry M. van den Heuvel, MD, PhD

Blood (2011) 118 (21): 1711.

https://doi.org/10.1182/blood.V118.21.1711.1711

Published: 2011

Journal Articles

Gemtuzumab Ozogamicin In Refractory Childhood Acute Myeloid Leukemia.

Dirk Reinhardt, MD, PhD, Christian M. Zwaan, MD, PhD, Annette Sander, Christine Neuhoff, Gertjan J. Kaspers, MD, PhD, Ursula Creutzig, MD

Blood (2010) 116 (21): 1075.

https://doi.org/10.1182/blood.V116.21.1075.1075

Published: 2010

Journal Articles

Clinical and Prognostic Significance of Eosinophilia and Inv(16)/t(16;16) In Pediatric Acute Myelomonocytic Leukemia (AML-M4).

Ingrid E.M. Bank, BsC, Válerie de Haas, MD, PhD, H. Berna Beverloo, PhD, Christian M. Zwaan, MD, PhD, Gertjan J. Kaspers, MD, PhD

Blood (2010) 116 (21): 1664.

https://doi.org/10.1182/blood.V116.21.1664.1664

Published: 2010

Journal Articles

High IGSF4 expression In Pediatric Acute Monoblastic Leukemia with t(9;11)

Eva A Coenen, MD, Jenny Kuipers, Brian V Balgobind, Jan Stary, Andre Baruchel, Valerie de Haas, Evelina S. De Bont, MD, PhD, Dirk Reinhardt, MD, PhD, Gertjan J. Kaspers, MD, PhD, Jacqueline Cloos, Astrid Danen-van Oorschot, Monique L. Den Boer, Rolf Marschalek, Claus Meyer, Rob Pieters, MD, PhD, Christian M. Zwaan, MD, PhD, Marry van den Heuvel-Eibrink

Blood (2010) 116 (21): 3614.

https://doi.org/10.1182/blood.V116.21.3614.3614

Published: 2010

Journal Articles

Myeloid Leukemia of Down Syndrome: The Results of An International Retrospective Study

Blood (2010) 116 (21): 2718.

https://doi.org/10.1182/blood.V116.21.2718.2718

Published: 2010

Journal Articles

Frequent Instability of Type I and II Aberrations Between Diagnosis and Relapse Observed in Pediatric Aml; Implications for Targeted Therapy and MRD Detection.

Costa Bachas, MSc, Gerrit-Jan Schuurhuis, Iris H.I.M. Hollink, MD, Bianca F. Goemans, MD, PhD, Dirk Reinhardt, MD, PhD, Christian M Zwaan, MD, PhD, Marry M. van den Heuvel, MD, PhD, Eveline S.J.M de Bont, Elisabeth R. Van Wering, Gertjan Kaspers, MD, PhD, Jacqueline Cloos, PhD

Blood (2009) 114 (22): 1624.

https://doi.org/10.1182/blood.V114.22.1624.1624

Published: 2009

Journal Articles

Identification of Gene Expression Signatures Accurately Predicting Cytogenetic Subtypes in Pediatric Acute Myeloid Leukemia.

Brian V Balgobind, MD, Marry M van den Heuvel-Eibrink, MD, PhD, Renee X Menezes, Dirk Reinhardt, MD, PhD, Iris H.I.M. Hollink, MD, Susan T.J.C.M. Arentsen-Peters, Elisabeth R van Wering, Gertjan Kaspers, MD, PhD, Jaqueline Cloos, PhD, Eveline S.J.M de Bont, Andre Baruchel, MD, Jean-Michel Cayuela, PhD, Jan Stary, MD, PhD, Jan Trka, MD., PhD, Berna Beverloo, PhD, Rob Pieters, Christian M Zwaan, MD, PhD, Monique L. Den Boer, MSc, PhD

Blood (2008) 112 (11): 1509.

https://doi.org/10.1182/blood.V112.11.1509.1509

Published: 2008

Journal Articles

EVI1 Overexpression in Pediatric Acute Myeloid Leukemia Associated with Unfavorable Subtypes.

Brian V Balgobind, MD, Sanne Lugthart, MD, Iris H.I.M. Hollink, MD, Susan T.J.C.M. Arentsen-Peters, Elisabeth R van Wering, Sibold S.N. de Graaf, MD, PhD, Dirk Reinhardt, MD, PhD, Gertjan Kaspers, MD, PhD, Jan Stary, MD, PhD, Jan Trka, MD, PhD, Martin Zimmermann, PhD, Ruud Delwel, PhD, Rob Pieters, Christian M Zwaan, MD, PhD, Marry M van den Heuvel-Eibrink, MD, PhD

Blood (2008) 112 (11): 1802.

https://doi.org/10.1182/blood.V112.11.1802.1802

Published: 2008

Journal Articles

Low Frequency of MLL -PTD Detected in Pediatric Acute Myeloid Leukemia Using MLPA Screening.

Brian Balgobind, MD, Iris H.I.M. Hollink, MD, Dirk Reinhardt, MD, PhD, Elisabeth R van Wering, Siebold S.N. de Graaf, MD, PhD, Andre Baruchel, MD, Jean-Michel Cayuela, PhD, Rob Pieters, Christian M Zwaan, MD, PhD, Marry M van den Heuvel-Eibrink, MD, PhD

Blood (2008) 112 (11): 1512.

https://doi.org/10.1182/blood.V112.11.1512.1512

Published: 2008

NARROW

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

A Double Blind Randomised Clinical Trial to Prevent Serious Side Effects of Dexamethasone during Pediatric Acute Lymphoblastic Leukemia Treatment

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

Molecular Aberrations in 107 Children with Myelodysplastic Syndrome (MDS).

Glucocorticoid-Induced Proliferation and Differentiation of Untreated Pediatric AML Cells

IER3 Expression in Childhood Myelodysplastic Syndrome,

Acute Lymphoblastic Leukemia in Children with Down Syndrome: A Report From the Ponte Di Legno Study Group,

Germline Mitochondrial DNA Mutations As a Novel First Event in Childhood Myelodysplastic Syndrome

Gemtuzumab Ozogamicin In Refractory Childhood Acute Myeloid Leukemia.

Clinical and Prognostic Significance of Eosinophilia and Inv(16)/t(16;16) In Pediatric Acute Myelomonocytic Leukemia (AML-M4).

High IGSF4 expression In Pediatric Acute Monoblastic Leukemia with t(9;11)

Myeloid Leukemia of Down Syndrome: The Results of An International Retrospective Study

Frequent Instability of Type I and II Aberrations Between Diagnosis and Relapse Observed in Pediatric Aml; Implications for Targeted Therapy and MRD Detection.

Identification of Gene Expression Signatures Accurately Predicting Cytogenetic Subtypes in Pediatric Acute Myeloid Leukemia.

EVI1 Overexpression in Pediatric Acute Myeloid Leukemia Associated with Unfavorable Subtypes.

Low Frequency of MLL -PTD Detected in Pediatric Acute Myeloid Leukemia Using MLPA Screening.

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American Society of Hematology

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American Society of Hematology

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