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Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142513

Published: 2020

Journal Articles

Siglec-15 Is a Novel Immunomodulatory Protein and Therapeutic Target in Childhood Leukemia

Claire E. Pillsbury, Jairo A. Fonseca, MD, Jodi Dougan, Hasan Abukharma, Linda N. Liu, PhD, Christopher C. Porter, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-142833

Published: 2020

Journal Articles

Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia

Anthony Ross, MD, Miyoung Lee, PhD, Jamie Hamilton, Raira Ank, Priscilla Do, PhD, Jamie Story, Sunil S. Raikar, MD, Erik Dreaden, PhD, Christopher C. Porter, MD, Curtis J. Henry, PhD

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-136573

Published: 2020

Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2316.

https://doi.org/10.1182/blood-2019-132032

Published: 2019

Journal Articles

Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms

Blood (2018) 132 (Supplement 1): 5849.

https://doi.org/10.1182/blood-2018-99-118979

Published: 2018

Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 1035.

https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035

Published: 2017

Journal Articles

IFN-γ Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils

Michael A Ellison, PhD, Christy M Gearheart, PhD, Christopher C. Porter, MD, Daniel R. Ambruso, MD

Blood (2016) 128 (22): 1328.

https://doi.org/10.1182/blood.V128.22.1328.1328

Published: 2016

Journal Articles

ETV6 Regulates Pax5 Expression in Early B Cell Development

Courtney L. Jones, PhD, Gregory Kirkpatrick, Courtney Fleenor, Welsh Seth, Leila J Noetzli, BS, Susan Fosmire, Dmitry Baturin, Xiayuan Liang, MD, Giovanny Hernandez, Eric Martin Pietras, PhD, Craig T Jordan, PhD, Jesse W Rowley, PhD, Jorge Di Paola, MD, James R. Hagman, Christopher C. Porter, MD

Blood (2016) 128 (22): 2655.

https://doi.org/10.1182/blood.V128.22.2655.2655

Published: 2016

Journal Articles

A Dominant Negative Mutation (p.P214L) in ETV6 is Associated with Megakaryocyte and Erythroid Transcript Misregulation

Leila Noetzli, BS, Jesse W Rowley, PhD, Michael U Callaghan, MD, Madhvi Rajpurkar, MD, Alisa B. Lee-Sherick, MD, Christopher C. Porter, MD, Andrew S. Weyrich, PhD, Jorge A. Di Paola, MD

Blood (2015) 126 (23): 76.

https://doi.org/10.1182/blood.V126.23.76.76

Published: 2015

Journal Articles

Combined Inhibition of Wee1 and Poly(ADP Ribose) Polymerase1/2 Synergistically Inhibits Acute Myeloid Leukemia Cells By Enhancing DNA Damage and the Induction of Apoptosis

Jonathan C Snedeker, Tamara M Burleson, Raoul Tibes, MD PhD, Christopher C. Porter, MD

Blood (2014) 124 (21): 3621.

https://doi.org/10.1182/blood.V124.21.3621.3621

Published: 2014

Journal Articles

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

Courtney L Jones, PhD, Christy M Gearheart, PhD, Susan Fosmire, Cristina Delgado-Martin, PhD, Faye Pais, MD, Jinhua Wang, PhD, Teena Bhatla, MD, Danielle S Bitterman, Simone R de Rijk, Wallace Bourgeois, Smita C. Dandekar, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD PhD, Michael J Garabedian, PhD, Christopher C. Porter, MD, William L. Carroll, MD

Blood (2014) 124 (21): 789.

https://doi.org/10.1182/blood.V124.21.789.789

Published: 2014

Journal Articles

Genome-Wide shRNA Screen Implicates Mitogen Activated Protein Kinase (MAPK) Pathway In Glucocorticoid Resistance In Acute Lymphoblastic Leukemia

Jones L. Courtney, Christy M. Gearheart, Ph.D., Fosmire Susan, Wang Jinhua, Ph.D., Danielle S. Bitterman, Teena Bhatla, MD, Wallace Bourgeois, Christopher C. Porter, MD, William L. Carroll, MD

Blood (2013) 122 (21): 1296.

https://doi.org/10.1182/blood.V122.21.1296.1296

Published: 2013

Journal Articles

Inhibition Of Wee1 Enhances The Anti-Leukemic Effects Of Antimetabolites In Vitro and In Vivo

James B. Ford, DO, Susan Fosmire, Annemie van Linden, Ph.D., Dmitry Baturin, MD/PhD, Christopher C. Porter, MD

Blood (2013) 122 (21): 1281.

https://doi.org/10.1182/blood.V122.21.1281.1281

Published: 2013

Journal Articles

Genome-Wide shRNA Screen Identifies WEE1 As a Critical Mediator of Cell Fate and Novel Therapeutic Target in AML,

Christopher C. Porter, MD, Jihye Kim, Ph.D., Susan Fosmire, Christy M. Gearheart, Ph.D., Annemie van Linden, Ph.D., Vadym Zaberezhnyy, Dexiang Gao, Ph.D., Aik Choon Tan, Ph.D., James DeGregori, Ph.D.

Blood (2011) 118 (21): 3503.

https://doi.org/10.1182/blood.V118.21.3503.3503

Published: 2011

Journal Articles

Knockdown of HPRT Enables Selection of Genetically Modified Human Hematopoietic Progenitor Cells.

Rashmi Choudhary, Ph.D., Brian Freed, Ph.D., James DeGregori, Christopher C. Porter, MD

Blood (2010) 116 (21): 3772.

https://doi.org/10.1182/blood.V116.21.3772.3772

Published: 2010

Journal Articles

The Addition of Cyclosporine to Dasatinib Therapy of Murine Bcr-Abl + Leukemia Improves Disease Control Independent of Altered Pharmacokinetics

Christopher C. Porter, MD, Mark A. Gregory, Ph.D., Vadym Zaberezhnyy, Jelena Klawitter, Ph.D., Uwe Christians, Ph.D., James DeGregori, Ph.D.

Blood (2010) 116 (21): 600.

https://doi.org/10.1182/blood.V116.21.600.600

Published: 2010

Journal Articles

In Vitro and In Vivo Selection of Genetically Modified Cells Using shRNA Against HPRT and Treatment with 6-thioguanine.

Christopher C. Porter, MD, James DeGregori

Blood (2007) 110 (11): 2590.

https://doi.org/10.1182/blood.V110.11.2590.2590

Published: 2007

Journal Articles

The Leukemia Oncogene E2a-Hlf Impairs Checkpoint Activation.

Christopher C. Porter, MD, James V. DeGregori, PhD

Blood (2005) 106 (11): 2857.

https://doi.org/10.1182/blood.V106.11.2857.2857

Published: 2005

Journal Articles

BCL-6 Overexpression Predicts Poor Response to Reduced Immune Suppression Therapy in Children with Post-Transplantation Lymphoproliferative Disease (PTLD).

Christopher C. Porter, MD, Xiayuan Liang, MD, Edythe A. Albano, MD

Blood (2004) 104 (11): 4342.

https://doi.org/10.1182/blood.V104.11.4342.4342

Published: 2004

NARROW

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Siglec-15 Is a Novel Immunomodulatory Protein and Therapeutic Target in Childhood Leukemia

Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

IFN-γ Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils

ETV6 Regulates Pax5 Expression in Early B Cell Development

A Dominant Negative Mutation (p.P214L) in ETV6 is Associated with Megakaryocyte and Erythroid Transcript Misregulation

Combined Inhibition of Wee1 and Poly(ADP Ribose) Polymerase1/2 Synergistically Inhibits Acute Myeloid Leukemia Cells By Enhancing DNA Damage and the Induction of Apoptosis

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

Genome-Wide shRNA Screen Implicates Mitogen Activated Protein Kinase (MAPK) Pathway In Glucocorticoid Resistance In Acute Lymphoblastic Leukemia

Inhibition Of Wee1 Enhances The Anti-Leukemic Effects Of Antimetabolites In Vitro and In Vivo

Genome-Wide shRNA Screen Identifies WEE1 As a Critical Mediator of Cell Fate and Novel Therapeutic Target in AML,

Knockdown of HPRT Enables Selection of Genetically Modified Human Hematopoietic Progenitor Cells.

The Addition of Cyclosporine to Dasatinib Therapy of Murine Bcr-Abl + Leukemia Improves Disease Control Independent of Altered Pharmacokinetics

In Vitro and In Vivo Selection of Genetically Modified Cells Using shRNA Against HPRT and Treatment with 6-thioguanine.

The Leukemia Oncogene E2a-Hlf Impairs Checkpoint Activation.

BCL-6 Overexpression Predicts Poor Response to Reduced Immune Suppression Therapy in Children with Post-Transplantation Lymphoproliferative Disease (PTLD).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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