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Chung Hoow Kok, PhD
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Journal Articles

Therapy-Related Myeloid Neoplasm Has a Distinct Pro-Inflammatory Bone Marrow Microenvironment and Delayed DNA Damage Repair

Monika M Kutyna, MSc, Li Yan A Wee, BSc (Hons), Sharon Paton, BSc, Dimitrios Cakouros, PhD, Agnieszka Arthur, PhD, Rakchha Chhetri, MBBS, Andreas W Schreiber, PhD, Chung Hoow Kok, PhD BSc, Deepak Singhal, MBBS,MDFRACP,FRCPA, Daniel Thomas, MD PhD, Timothy P. Hughes, MDMBBS,FRACP,FRCPA, David Campbell, PhD B.M.B.S., F.R.A.C.S., F.A.Oth.A, Stan Gronthos, PhD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-137277
Published: 2020
Journal Articles

A Combination of CD302 gene Expression and 3-Months BCR-ABL1 Level Predicts Inferior Achievement of Deep Molecular Response in CP-CML Patients Treated with Imatinib

Chung Hoow Kok, PhD BSc, Liu Liu, PhD BSc, David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Verity A Saunders, Phuong Dang, Timothy P. Hughes, MDMBBS,FRACP,FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 663.
https://doi.org/10.1182/blood-2019-125446
Published: 2019
Journal Articles

Integration of Multiple Bioassays Using Machine Learning to Identify High-Risk CP-CML Patients Treated with Frontline Imatinib

Chung Hoow Kok, PhD BSc, Sakrapee Paisitkriangkrai, PhD, David T Yeung, PhD BSc, FRACP, FRCPA MBBS, Liu Liu, PhD BSc, Verity A Saunders, Phuong Dang, Agnes S. M. Yong, MD PhD, Deborah L White, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2018) 132 (Supplement 1): 1728.
https://doi.org/10.1182/blood-2018-99-117633
Published: 2018
Journal Articles

In Vitro Modeling of Ph-like ALL Fusions Identifies Novel Kinase-Domain Mutations As Mode of TKI-Resistance - Implications for Targeted Therapy

Kartini Asari, Susan L Heatley, PhD MD, Teresa Sadras, PhD, Tamara M Leclercq, PhD, Stephen Fitter, PhD, Chung Hoow Kok, PhD, Andrew C W Zannettino, PhD, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2016) 128 (22): 3957.
https://doi.org/10.1182/blood.V128.22.3957.3957
Published: 2016
Journal Articles

A 20 Gene Expression Signature That Predicts Early Molecular Response Failure in Chronic Phase CML Patients Treated with Frontline Imatinib

Chung Hoow Kok, PhD, Tamara M Leclercq, PhD, Dale Watkins, PhD, David T Yeung, BSc, MBBS, FRACP, FRCPA, Verity A Saunders, BSc (Hons), Deborah L White, PhD FFSc (RCPA), Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2015) 126 (23): 596.
https://doi.org/10.1182/blood.V126.23.596.596
Published: 2015
Journal Articles

High Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Transcriptional Activity Reduces Active Influx of Imatinib and Kinase Inhibition in CML Cells

Jueqiong WANG, PhD, Chung Hoow Kok, PhD, Tamara M Leclercq, PhD, Verity A Saunders, BSc (Hons), Richard J D'Andrea, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2015) 126 (23): 2770.
https://doi.org/10.1182/blood.V126.23.2770.2770
Published: 2015
Journal Articles

High Prevalence of Relapse in Australian Children with Ph-like Acute Lymphoblastic Leukemia Despite Risk Adapted Treatment

Susan L Heatley, PhD MD, Teresa Sadras, PhD, Eva Nievergall, PhD, Chung Hoow Kok, PhD, Phuong Dang, BSci (Hon), Kelly Quek, PhD, Nicola C Venn, Sarah Moore, BSc (Hon), FFSc (RCPA), Tamara Law, BSc (Hons), Anthea Ng, BAppSc, MSc, Murray D Norris, PhD, Tamas Revesz, MD PhD, Michael P Osborn, MBBS, Chris Fraser, FRACP, MBBS, MPH, Frank Alvaro, MBBS, FRACP, Glenn M Marshall, MBBS, MD FRACP, Luciano Dalla Pozza, MBBS, FRACP, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Charles G. Mullighan, MBBS, MSc, MD, Rosemary Sutton, PhD, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2015) 126 (23): 1419.
https://doi.org/10.1182/blood.V126.23.1419.1419
Published: 2015
Journal Articles

Role Of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Its Ligands In The Regulation Of Functional OCT-1 Activity In CML Cells

Jueqiong Wang, PhD, Chung Hoow Kok, PhD, Richard J. D'Andrea, PhD, Timothy P. Hughes, MD, MBBS, Deborah L. White, PhD, FFSc(RCPA)
Journal: Blood
Blood (2013) 122 (21): 1470.
https://doi.org/10.1182/blood.V122.21.1470.1470
Published: 2013
Journal Articles

Global DNA Methylation Analysis Identifies Key Pathway Differences Between Poor (Low OCT-1 Activity) and Standard Risk CP-CML Patients At Diagnosis

Dale B. Watkins, B.Sc. (Hons), Chung Hoow Kok, PhD, Richard J. D'Andrea, PhD, Timothy P. Hughes, MD, MBBS, Deborah L. White, PhD, FFSc(RCPA)
Journal: Blood
Blood (2012) 120 (21): 3730.
https://doi.org/10.1182/blood.V120.21.3730.3730
Published: 2012
Journal Articles

Non-Steroidal Anti-Inflammatory Drugs and Imatinib; Drug Interactions That May Impact Efficacy,

Jueqiong Wang, MMed, Timothy P Hughes, MD, MBBS, Chung Hoow Kok, PhD, Verity A Saunders, BScHons, Amity Frede, BScHons, Kelvin GrootObbink, BScHons, Michael Philip Osborn, MBBS, Andrew A Somogyi, PhD, Richard J D'Andrea, PhD, Deborah L. White, PhD. FFSc(RCPA)
Journal: Blood
Blood (2011) 118 (21): 3501.
https://doi.org/10.1182/blood.V118.21.3501.3501
Published: 2011
Journal Articles

Differential Lineage Involvement Between Very Low and Higher OCT-1 Activity Chronic-Phase CML Patients

Dale B. Watkins, B.Sc. (Hons), Chung Hoow Kok, PhD, Timothy P. Hughes, MD, MBBS, Cassandra Slader, PhD, Richard D'Andrea, PhD, Deborah L. White, PhD. FFSc(RCPA)
Journal: Blood
Blood (2011) 118 (21): 1675.
https://doi.org/10.1182/blood.V118.21.1675.1675
Published: 2011