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Ciaran M Lee, PhD
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Journal Articles

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

So Hyun Park, BS, Ciaran M Lee, PhD, Yankai Zhang, PhD, Alicia Chang, MD, Vivien A Sheehan, MD PhD, Gang Bao, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2018-99-114241
Published: 2018
Journal Articles

Highly Efficient Editing of the Beta-Globin Gene in Patient Derived Hematopoietic Stem and Progenitor Cells to Treat Sickle Cell Disease

So Hyun Park, BS, Ciaran M Lee, PhD, Daniel P. Dever, PhD, Timothy H Davis, BS, Joab Camarena, BS, Yankai Zhang, PhD, Matthew Porteus, MD PhD, Vivian A Sheehan, MD PhD, Gang Bao, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2192.
https://doi.org/10.1182/blood-2018-99-117371
Published: 2018
Journal Articles

Persistence of CRISPR/Cas9-Edited Hematopoietic Stem and Progenitor Cells and Reactivation of Fetal Hemoglobin in Nonhuman Primates

Olivier Humbert, PhD, Stefan Radtke, PhD, Ray R Carillo, Anai M Perez, Sowmya Somashekar Reddy, Lauren E Schefter, Christopher Lux, MDPhD, Sowmya Pattabhi, PhD, Olivier Negre, PhD, Ciaran M Lee, PhD, Jennifer Adair, PhD, Christopher Peterson, PhD, Gang Bao, PhD, David J. Rawlings, MD, Andrew M. Scharenberg, MD, Hans-Peter Kiem, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 806.
https://doi.org/10.1182/blood-2018-99-112996
Published: 2018
Journal Articles

Sickle Human Umbilical Cord Derived Erythroid Progenitor Cells (S-HUDEP2): An Ideal in-Vitro System for Screening Anti-Sickling Compounds for Sickle Cell Disease

Alicia Chang, MD, So Hyun Park, BS, Ciaran M Lee, PhD, Alireza Paikari, MD, Gang Bao, PhD, Vivien A Sheehan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3675.
https://doi.org/10.1182/blood-2018-99-117158
Published: 2018
Journal Articles

Therapeutic Crispr/Cas9 Genome Editing for Treating Sickle Cell Disease

So Hyun Park, BS, Ciaran M Lee, PhD, Harshavardhan Deshmukh, MS, Gang Bao, PhD
Journal: Blood
Blood (2016) 128 (22): 4703.
https://doi.org/10.1182/blood.V128.22.4703.4703
Published: 2016
Journal Articles

Re-Creating Hereditary Persistence of Fetal Hemoglobin (HPFH) to Treat Sickle Cell Disease (SCD) and β-Thalassemia

Michelle I Lin, PhD, Elizabeth J Paik, PhD, Bibhu P Mishra, PhD, Song Chou, PhD, Ying Zhang, PhD, Kaleigh Tomkinson, MS, Michael A Pettiglio, BS, Andrew Sanginario, BS, Amanda Woo, BS, Min Jin Lee, BS, Melanie Allen, MS, Thomas J Cradick, PhD, Tirtha Chakraborty, PhD, Matthew Porteus, MD PhD, Ciaran M Lee, PhD, Gang Bao, PhD, Annarita Miccio, PhD, Annalisa Lattanzi, PhD, Fulvio Mavilio, PhD, Chad A Cowan, PhD, Rodger Novak, MD, Ante S Lundberg, MD
Journal: Blood
Blood (2016) 128 (22): 4708.
https://doi.org/10.1182/blood.V128.22.4708.4708
Published: 2016