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Claire Seedhouse, PhD
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Journal Articles

DNA Damaging Agents Cause a Sub-Cellular Re-Localisation of Nucleophosmin in an npm1 Mutated Acute Myeloid Leukemia (AML) Cell Line and in Primary AML Cells Carrying an npm1 Mutation

Graham D. Bailey, PhD, Asma Akhtar, BSc, Nigel H. Russell, Claire Seedhouse, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1251.
https://doi.org/10.1182/blood.V130.Suppl_1.1251.1251
Published: 2017
Journal Articles

Effectiveness of Transcriptional CDK Inhibitors in Targeting Non-Proliferating CD34+CD38- AML Cells,

Monica Pallis, PhD, Francis Burrows, PhD, Abigail Whittall, B Med Sci, Claire Seedhouse, PhD, Nicholas Boddy, B Med Sci, Nigel H. Russell, MD
Journal: Blood
Blood (2011) 118 (21): 3482.
https://doi.org/10.1182/blood.V118.21.3482.3482
Published: 2011
Journal Articles

Regulation of ABCB1 (p-glycoprotein) by the FOXO1 Transcription Factor in Acute Myeloid Leukemia.

Claire Seedhouse, PhD, Sophie Ahluwalia, BSc, Ken I Mills, Ph.D., FRCPath, Martin Grundy, BSc, Shili Shang, MD, MSc, Alan K. Burnett, MD, FRCP, Nigel H. Russell, MD, Monica Pallis, PhD
Journal: Blood
Blood (2009) 114 (22): 589.
https://doi.org/10.1182/blood.V114.22.589.589
Published: 2009
Journal Articles

Impaired S Phase Arrest in AML Cells with a FLT3-ITD Treated with Clofarabine Allows Prolonged Drug exposure to Reverse the Chemoresistant Phenotype.

Claire Seedhouse, PhD, Martin Grundy, BSc, Shili Shang, MD, MSc, John Ronan, CSci, FIBMS, Heather Pimblett, Nigel H. Russell, MD, Monica Pallis, PhD
Journal: Blood
Blood (2009) 114 (22): 1000.
https://doi.org/10.1182/blood.V114.22.1000.1000
Published: 2009
Journal Articles

The Telomerase Inhibitor RHPS4 Induces Telomere Shortening, DNA-Damage and Cell Death in AML Cells and Chemosensitises Cells to Daunorubicin.

Monica Pallis, PhD, Dotun Ojo, Jaineeta Richardson, MSc, John Ronan, CSci, FIBMS, Malcolm Stevens, PhD, FRS, Nigel H. Russell, MD, Claire Seedhouse, PhD
Journal: Blood
Blood (2009) 114 (22): 2760.
https://doi.org/10.1182/blood.V114.22.2760.2760
Published: 2009
Journal Articles

Genetic Polymorphisms of DNA-Repair- and Detoxification Enzymes in Therapy-Related AML and MDS.

Stephanie Fischer, Claire Seedhouse, PhD, Thomas Schulz, PhD, Ulrich Germing, PhD, MD, Lorenz H. Truemper, PhD, MD, Detlef Haase, PhD, MD
Journal: Blood
Blood (2007) 110 (11): 4223.
https://doi.org/10.1182/blood.V110.11.4223.4223
Published: 2007
Journal Articles

P-Glycoprotein Is Downregulated in KG1a Primitive Leukaemia Cells by LDL Cholesterol Deprivation and by HMG-CoA Reductase Inhibitors.

Laura Connelly-Smith, MBBCh, Joanne Pattinson, Martin Grundy, Shili Shang, Claire Seedhouse, PhD, Nigel Russell, MBChB, Monica Pallis, PhD
Journal: Blood
Blood (2007) 110 (11): 4192.
https://doi.org/10.1182/blood.V110.11.4192.4192
Published: 2007
Journal Articles

Polymorphisms in Human Homeobox HLX1 and DNA Repair RAD51 Genes Increase the Risk of Therapy-Related Acute Myeloid Leukemia.

Mays Jawad, PhD, Claire Seedhouse, PhD, Nigel H. Russell, MD, Mark Plumb, PhD
Journal: Blood
Blood (2006) 108 (11): 1171.
https://doi.org/10.1182/blood.V108.11.1171.1171
Published: 2006
Journal Articles

A Role for DNA Double Strand Breaks in the Sensitivity of AML Cells to Clofarabine: Enhanced In Vitro Sensitivity in Primary AML Cells with FLT3 Mutations.

Monica Pallis, PhD, Martin Grundy, BSc, Claire Seedhouse, PhD, Heather Pimblett, B Med Sci, Nigel Russell, MD
Journal: Blood
Blood (2006) 108 (11): 2582.
https://doi.org/10.1182/blood.V108.11.2582.2582
Published: 2006