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Daniel J. DeAngelo, MDPhD
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Journal Articles

The Safety and Activity of BMS-906024, a Gamma Secretase Inhibitor (GSI) with Anti-Notch Activity, in Patients with Relapsed T-Cell Acute Lymphoblastic Leukemia (T-ALL): Initial Results of a Phase 1 Trial

Patrick A. Zweidler-McKay, MDPhD, Daniel J. DeAngelo, MDPhD, Dan Douer, MD, Hervé Dombret, MD, Oliver G. Ottmann, MD, Norbert Vey, MD, Deborah A. Thomas, MD, Lili Zhu, MSc, Fei Huang, PhD, Gaurav Bajaj, PhD, Bruce S. Fischer, MD
Journal: Blood
Blood (2014) 124 (21): 968.
https://doi.org/10.1182/blood.V124.21.968.968
Published: 2014
Journal Articles

Ontogeny-Specific Patterns of Genetic Alterations in Acute Myeloid Leukemia

R. Coleman Lindsley, MDPhD, Brenton G. Mar, MDPhD, Emanuele Mazzola, PhD, Peter Grauman, Sarah Shareef, Daniel J. DeAngelo, MDPhD, Donna S. Neuberg, ScD, Richard M. Stone, MD, Benjamin L. Ebert, MD DPhil
Journal: Blood
Blood (2014) 124 (21): 18.
https://doi.org/10.1182/blood.V124.21.18.18
Published: 2014
Journal Articles

Preclinical and Clinical Pharmacodynamics of Pan-Pim Inhibition By AZD1208 in Acute Myeloid Leukemia: Assessment of Pim Isoform Dependency for Bad and 4EBP1 Phosphorylation

Kristen A McEachern, PhD, Adriana E Tron, PhD, Greg O'Connor, Rachel DuPont, Francis D Gibbons, PhD, Lourdes Pablo, Karthick Vishwanathan, PhD, Patricia McCoon, PhD, Jorge E. Cortes, MD, Daniel J. DeAngelo, MDPhD, Mark D Minden, MDPhD, Geoffrey L. Uy, MD, Frank Neumann, MDPhD, Karen Keating, Dennis Huszar, PhD, J. Elizabeth Pease, PhD, Jeffrey Brown, PhD, J. Carl Barrett, PhD
Journal: Blood
Blood (2014) 124 (21): 906.
https://doi.org/10.1182/blood.V124.21.906.906
Published: 2014
Journal Articles

­Selective Inhibitor of Nuclear Export (SINE), Selinexor (KPT-330), Shows Remarkable Activity Against AML Leukemia-Initiating Cells

Julia Etchin, PhD, Bonnie Thi Le, M.S., Alex Kentsis, MD PhD, Marc R Mansour, MDPhD, Alla Berezovskaya, B.S., Richard M. Stone, MD, Ilene Galinsky, RNP, Daniel J. DeAngelo, MDPhD, Dilara McCauley, PhD, Michael Kauffman, MD PhD, Sharon Shacham, PhDMBA, Jean C.Y. Wang, MDPhD, Andrew L Kung, MD PhD, A. Thomas Look, MD
Journal: Blood
Blood (2014) 124 (21): 995.
https://doi.org/10.1182/blood.V124.21.995.995
Published: 2014