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Daniel Sasca, MD
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Journal Articles

Mutational Synergy Coordinately Remodels Chromatin Accessibility, Enhancer Landscape and 3-Dimensional DNA Topology to Alter Gene Expression during Leukemia Induction

Haiyang Yun, PhD, Shabana Vohra, PhD, Annalisa Mupo, PhD, George Giotopoulos, PhD, Daniel Sasca, MD, Sarah J. Horton, PhD, Shuchi Agrawal-Singh, PhD, Eshwar Meduri, PhD, Faisal Basheer, MBBChir, MA, PhD, Ludovica Marando, Malgorzata Gozdecka, PhD, Oliver M. Dovey, PhD, Xiaonan Wang, PhD, Paolo Gallipoli, PhD, Cameron Osborne, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 278.
https://doi.org/10.1182/blood-2019-122413
Published: 2019
Journal Articles

Contrasting Stage Dependent Requirements for the Histone Methyltransferase EZH2 during the Evolution of Acute Myeloid Leukemia

Faisal Basheer, MBBChir, MA, George Giotopoulos, PhD, Eshwar Meduri, PhD, Haiyang Yun, PhD, Milena Mazan, PhD, Olivia Sheppard, Daniel Sasca, MD, Malgorzata Gozdecka, PhD, George S. Vassiliou, MD PhD, Brian J.P Huntly
Journal: Blood
Blood (2017) 130 (Supplement 1): 1215.
https://doi.org/10.1182/blood.V130.Suppl_1.1215.1215
Published: 2017
Journal Articles

Early Loss of CREBBP Confers Malignant Stem Cell Properties on Lymphoid Progenitors

Brian J.P Huntly, MD PhD, Sarah Jayne Horton, BSc, PhD, George Giotopoulos, Haiyang Yun, MD PhD, Shabana Vohra, BSc, PhD, Olivia Sheppard, Bsc, PhD, Rachael Bashford-Rogers, PhD, Mamunur Rashid, PhD, Daniel Sasca, MD, Faisal Basheer, MBBChir, MA, Paolo Gallipoli, MD PhD, Jessica Okosun, Daniel James Hodson, MD PhD, Jude Fitzgibbon, Ming Du, David Adams
Journal: Blood
Blood (2016) 128 (22): 460.
https://doi.org/10.1182/blood.V128.22.460.460
Published: 2016
Journal Articles

Targeting Aberrant Ncam (neural cell adhesion molecule; CD56) Expression in Acute Myeloid Leukemia

Daniel Sasca, MD, Andrea Schueler, PhD, Jakub Szybinski, Oliver Kriege, MD, Kerstin Kunz, Eva Marie Fehr, MD, Patricia Haehnel, PhD, Wolf Henning Gebhardt, PhD, Gerge Reid, PhD, Matthias Theobald, MD PhD, Lars Bullinger, MD, Thomas Kindler, MD
Journal: Blood
Blood (2015) 126 (23): 311.
https://doi.org/10.1182/blood.V126.23.311.311
Published: 2015
Journal Articles

Expression Of FLT3-ITD Dysregulates The DBC1-Sirt1-p53 Signaling and Promotes Therapy Resistance

Daniel Sasca, MD, Patricia Haehnel, PhD, Kaml I.K. Khawaja, Birgit Enders, Lars Bullinger, MD, PhD, Matthias Theobald, MD, PhD, Thomas Kindler, MD
Journal: Blood
Blood (2013) 122 (21): 3789.
https://doi.org/10.1182/blood.V122.21.3789.3789
Published: 2013