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Daniela S Gerhard, PhD
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Journal Articles

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Samuel W. Brady, PhD, Zhaohui Gu, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Deqing Pei, MS, Cheng Cheng, PhD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Chunxu Qu, PhD, Ashley Hill, BS, Xiaotu Ma, Lei Wei, PhD, Sasi Arunachalam, PhD, Kohei Hagiwara, MD, Yangling Liu, Diane Flasch, Yu Liu, PhD, Matthew Parker, PhD, Xiaolong Chen, PhD, Yongjin Li, PhD, Yiping Fan, PhD, Robert Michael, PhD, Michael Rusch, BS, Mark Wilkinson, Scott Foy, PhD, Dale Hedges, PhD, Scott Newman, PhD, Xin Zhou, PhD, Jian Wang, Shalini C. Reshmi, PhD, Julie M. Gastier-Foster, PhD, Patee Gesuwan, Malcolm A Smith, MD PhD, Daniela S. Gerhard, PhD, Naomi Winick, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Eric Larsen, MD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, William L. Carroll, MD, Patrick A. Zweidler-McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, Stuart S. Winter, MD, Michael J. Burke, MD, Wanda L. Salzer, MD, Kimberly P. Dunsmore, Anne Angiolillo, MD, Kristine R Crews, PharmD, James R. Downing, MD, Sima Jeha, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 649.
https://doi.org/10.1182/blood-2019-124881
Published: 2019
Journal Articles

Evaluation of Cancer Testis Antigens (CTAs) As Immuno-Therapeutic Targets in Pediatric AML

Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, Tim Triche, PhD, Jason E. Farrar, MD, Todd A Alonzo, PhD, Yussanne Ma, PhD, Lisa Wei, BS, Jaime Guidry Auvil, PhD, Daniela S. Gerhard, PhD, Marco A Marra, PhD, Alan S Gamis, MD MPH, Anders Kolb, MD, Hamid Bolouri, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 107.
https://doi.org/10.1182/blood.V130.Suppl_1.107.107
Published: 2017
Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma

Bruno M. Grande, BSc, Daniela S. Gerhard, PhD, Nicholas B. Griner, PhD, Corey Casper, MD MPH, Constance Namirembe, Abraham Omoding, MD, Jackson Orem, MD, Sam M. Mbulaiteye, MD MBBChir, MPhil, Charles G. Mullighan, MBBS, MD, John T. Sandlund, MD, Thomas Alexander, MD MPH, John Kim Choi, MD, Jeremy S. Abramson, MD MMSc, Thomas G. Gross, MD PhD, Ariela Noy, MD, Jeffrey Bethony, PhD, Timothy C. Greiner, MS, MD, Elaine S. Jaffe, MD, Nancy Lee Harris, MD, Julie M. Gastier-Foster, PhD, Jay Bowen, MS, Hilary Allen, MS, Roland Schmitz, PhD, Wyndham H. Wilson, MD PhD, Jean Paul Martin, PhD, Marie-Reine Martin, MD, John D. Irvin, MD PhD, Maureen Dyer, PhD, Patee Gesuwan, Yiwen He, PhD, Tanja M. Davidsen, PhD, Karen Novik, PhD, Andrew J. Mungall, PhD, Yussanne Ma, PhD, Marco A. Marra, PhD, Ryan D. Morin, PhDBSc,MSc, Louis M. Staudt, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 39.
https://doi.org/10.1182/blood.V130.Suppl_1.39.39
Published: 2017
Journal Articles

Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative

Katherine Tarlock, MD, Allison J. Kaeding, Todd A. Alonzo, PhD, Michael R. Loken, PhD, Rhonda E. Ries, MA, Laura Pardo, Robert Gerbing, BS, Jason E Farrar, MD, Jaime M. Guidry Auvil, PhD, Daniela S. Gerhard, PhD, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Pattee Gesuwan, Leandro C. Hermida, Marco A. Marra, PhD, Andrew J. Mungall, Karen Mungall, PhD, Yussanne Ma, PhD, Stuart Zong, William Long, PhD, Alan S. Gamis, MD MPH, E. Anders Kolb, MD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2873.
https://doi.org/10.1182/blood.V128.22.2873.2873
Published: 2016
Journal Articles

Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction

Daniela S Gerhard, PhD, Bruno Grande, B. Sc., Nicholas Griner, PhD, Corey Casper, MD, Sarah E. Gerdts, MPH, Abraham Omoding, MD, Jackson Orem, MD, Sam M Mbulaiteye, MD, Martin D. Ogwang, MD, Steven J. Reynolds, MD MPH, Kishor Bhatia, PhD, Leona Ayers, MD, John K Choi, MD, Charles G. Mullighan, MBBS, MSc, PhD, John T. Sandlund, MD, Thomas B. Alexander, MD MPH, Jeremy S. Abramson, MD, Thomas G. Gross, MD PhD, Ariela Noy, MD PhD, Jeffrey Bethony, PhD, Fabio Leal, MD, PhD, Timothy C Greiner, MS, MD, Elaine S. Jaffe, MD, Nancy Lee Harris, MD, Julie M. Gastier-Foster, PhD, Jay Bowen, MS, Benjamin Hanf, Roland Schmitz, PhD, Jean-Paul Martin, MD, Marie-Reine Martin, MD, John D. Irvin, MD PhD, Ellen Miller, MS, Patee Gesuwan, Leandro C. Hermida, Tanja M. Davidsen, PhD, Andrew J. Mungall, Yussanne Ma, PhD, Marco A. Marra, PhD, Ryan D. Morin, Louis M. Staudt, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1760.
https://doi.org/10.1182/blood.V128.22.1760.1760
Published: 2016
Journal Articles

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Timothy Junius Triche, Jr., PhD, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi
Journal: Blood
Blood (2016) 128 (22): 595.
https://doi.org/10.1182/blood.V128.22.595.595
Published: 2016
Journal Articles

A microRNA Expression-Based Model Predicts Event Free Survival in Pediatric Acute Myeloid Leukemia

Emilia L. Lim, PhD, Diane L. Trinh, MSc, Rhonda E. Ries, MA, Jim Wang, Yussanne Ma, PhD, James Topham, Maya D. Hughes, MD, Erin Pleasance, PhD, Andrew J. Mungall, Richard Moore, PhD, Yongjun Zhao, PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Daniela S. Gerhard, PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD
Journal: Blood
Blood (2016) 128 (22): 1210.
https://doi.org/10.1182/blood.V128.22.1210.1210
Published: 2016
Journal Articles

Divergent Epigenomes in Pediatric and Adult Acute Myeloid Leukemia Implicate Cell of Origin and Transcriptional Silencing of Immune Responses As Sources of Clinically Relevant Heterogeneity: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Timothy Junius Triche, Jr., PhD, Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan Gamis, MD, Malcolm A. Smith, MD PhD, Stephen R Piccolo, PhD, Daniela S Gerhard, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1046.
https://doi.org/10.1182/blood.V128.22.1046.1046
Published: 2016
Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2016) 128 (22): 454.
https://doi.org/10.1182/blood.V128.22.454.454
Published: 2016
Journal Articles

Alteration of Chromatin Modifiers and Misregulation of Transcription Factors Define the Genomic Profile of Infant AML

Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E Farrar, MD, Emilia L. Lim, PhD, Timothy Junius Triche, Jr., PhD, Katherine Tarlock, MD, Jaime Guidry Auvil, PhD, Betsy A. Hirsch, PhD, Susana C. Raimondi, PhD, Yussanne Ma, PhD, Marco A. Marra, PhD, Richard Aplenc, MD PhD, Erin M. Guest, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 774.
https://doi.org/10.1182/blood.V128.22.774.774
Published: 2016
Journal Articles

TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative

Matthew A. Kutny, MD, Todd A. Alonzo, PhD, Yi-Cheng Wang, MS, Rhonda Ries, MA, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, William Long, PhD, Yussanne Ma, PhD, Stuart Zong, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1368.
https://doi.org/10.1182/blood.V126.23.1368.1368
Published: 2015
Journal Articles

ASXL1 and ASXL2 Mutations in Childhood AML Are Strongly Associated with t(8;21) but Do Not Independently Impact on Prognosis: A Report from the Children's Oncology Group and NCI/COG Target Initiative

Jason E. Farrar, MD, Todd A. Alonzo, PhD, Rhonda E. Ries, MA, Robert B. Gerbing, MA, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Karen Mungall, PhD, Yussanne Ma, PhD, William Long, PhD, Stuart Zong, E. Anders Kolb, MD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2587.
https://doi.org/10.1182/blood.V126.23.2587.2587
Published: 2015
Journal Articles

Comprehensive Sequence Analysis of Relapse and Refractory Pediatric Acute Myeloid Leukemia Identifies miRNA and mRNA Transcripts Associated with Treatment Resistance - a Report from the COG/NCI-Target AML Initiative

Emilia L. Lim, Diane L. Trinh, MSc, Rhonda E. Ries, MA, Yussanne Ma, PhD, James Topham, Maya D. Hughes, MD, Erin Pleasance, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, Yongjun Zhao, PhD, Daniela S. Gerhard, PhD, Vivian Oehler, MD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Todd A. Alonzo, PhD, Robert J. Arceci, MD PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD
Journal: Blood
Blood (2015) 126 (23): 687.
https://doi.org/10.1182/blood.V126.23.687.687
Published: 2015
Journal Articles

The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia

Yu Liu, PhD, John Easton, PhD, Ying Shao, Mark Wilkinson, Michael Edmonson, PhD, Xiaotu Ma, PhD, Malcolm A. Smith, MD PhD, Michael Rusch, BA, Jaime Guidry Auvil, Daniela S. Gerhard, PhD, Mary V. Relling, PharmD, Naomi J. Winick, MD, Elizabeth Raetz, MD, Meenakshi Devidas, PhD, Cheryl L. Willman, MD, Richard C. Harvey, PhD, William L. Carroll, MD, Kimberly P. Dunsmore, MD, Stuart S. Winter, MD, Brent L Wood, MD PhD, James R. Downing, MD, Mignon L. Loh, MD, Stephen P Hunger, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MSc, MD
Journal: Blood
Blood (2015) 126 (23): 691.
https://doi.org/10.1182/blood.V126.23.691.691
Published: 2015
Journal Articles

Comprehensive Genomic and Transcript Profiling of CBL Gene in Childhood AML: A Report from Children's Oncology Group Studies AAML03P1, AAML0531 and COG/NCI Target AML Initiative

Diana Chin, Matthew A. Kutny, MD, Jonathan Grim, MD PhD, Robert B. Gerbing, MA, Kristen Miller, BS, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, William Long, PhD, Yussanne Ma, PhD, Stuart Zong, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 170.
https://doi.org/10.1182/blood.V126.23.170.170
Published: 2015
Journal Articles

Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative

Fabiana Ostronoff, MD, Rhonda E. Ries, MA, Robert B. Gerbing, MA, Marco A Marra, PhD, Ma Yussanne, William Long, PhD, Stuart Zong, Karen Mungall, PhD, Andrew Andrew, Daniela S. Gerhard, PhD, Malcolm A. Smith, MD PhD, Gesuwan Patee, Tanja M. Davidsen, PhD, Leandro C. Hermida, Jason E. Farrar, MD, Jaime Guidry Auvil, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 169.
https://doi.org/10.1182/blood.V126.23.169.169
Published: 2015
Journal Articles

CSF3R Mutations Represent a Novel Therapeutic Target in Pediatric AML with a High Degree of Overlap with CEBPA Mutations: a Report from COG AAML0531 and COG/NCI Target AML Initiative

Julia Elizabeth Maxson, PhD, Rhonda Ries, MA, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, E. Anders Kolb, MD, Sarah L Thompson, Jaime M. Guidry Auvil, PhD, Marco A Marra, PhD, Yussanne Ma, PhD, Stuart Zong, Andrew J. Mungall, PhD, Richard Moore, PhD, William Long, PhD, Patee Gesuwan, Tanja M. Davidsen, PhD, Leandro C. Hermida, Jason E. Farrar, MD, Jerald P. Radich, MD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Alan S. Gamis, MD MPH, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 174.
https://doi.org/10.1182/blood.V126.23.174.174
Published: 2015
Journal Articles

Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative

Katherine Tarlock, MD, M. Eva Hansen, Tiffany Hylkema, Rhonda Ries, MA, Jason E. Farrar, MD, Jaime Guidry Auvil, Daniela S. Gerhard, PhD, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Karen Mungall, PhD, Yussanne Ma, Stuart Zong, William Long, PhD, Titus Boggon, PhD, Todd A. Alonzo, PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 87.
https://doi.org/10.1182/blood.V126.23.87.87
Published: 2015
Journal Articles

A Genome-Wide Association Study of Susceptibility to Acute Lymphoblastic Leukemia in Adolescents and Young Adults

Virginia Perez-Andreu, MDPhD, Kathryn G. Roberts, PhD, Xu Heng, PhD, Colton Smith, PhD, Hui Zhang, MD PhD, Wenjian Yang, PhD, Richard C. Harvey, PhD, Debbie Payne-Turner, BS, Meenakshi Devidas, PhD, I-Ming Cheng, DVM, William L. Carroll, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Elizabeth A. Raetz, MD, Julie M. Gastier-Foster, PhD, Guido Marcucci, MD, Clara D. Bloomfield, MD, Krzysztof Mrózek, MD PhD, Jessica Kohlschmidt, PhD, Wendy Stock, MD, Steven M. Kornblau, MD, Marina Konopleva, MD PhD, Elisabeth Paietta, PhD, Jacob M. Rowe, MD, Selina M. Luger, MD, Martin S. Tallman, MD, Ching-Hon Pui, MD, Sima Jeha, MD, Mary V. Relling, PharmD, William E. Evans, PharmD, Daniela S. Gerhard, PhD, Mignon L. Loh, MD, Cheryl L. Willman, MD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MSc, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2014) 124 (21): 132.
https://doi.org/10.1182/blood.V124.21.132.132
Published: 2014