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Journal Articles

Outcome of Children with Different Non-Malignant Disorders Given Alphabeta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Pietro Merli, MD, Daria Pagliara, MD PhD, Federica Galaverna, MD PhD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Stefania Gaspari, MD, Emilia Boccieri, MD, Marco Becilli, MD, Giovanna Del Principe, MD, Olivia Marini, PhD, Francesca Del Bufalo, MD, Francesco Quagliarella, MD, Antonio Giacomo Grasso, MD, Tiziana Corsetti, PhD, Matteo Di Nardo, MD, Luisa Strocchio, MD, Mattia Algeri, MD, Franco Locatelli, MD PhD

Blood (2020) 136 (Supplement 1): 2–4.

https://doi.org/10.1182/blood-2020-142703

Published: 2020

Journal Articles

Long-Term Outcome of Children with Acute Leukemia (AL) Given Alphabeta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Pietro Merli, MD, Daria Pagliara, MD PhD, Mattia Algeri, MD, Federica Galaverna, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Mauro Montanari, MD, Giovanna Leone, MD, Stefania Gaspari, MD, Michele Massa, MD, Valentina Cirillo, PhD, Maria Giuseppina Cefalo, MD, Simone Biagini, MSc, Marco Becilli, MD, Elia Girolami, MSc, Roberto Carta, MD, Annalisa Ruggeri, MD, Franco Locatelli, MD PhD

Blood (2019) 134 (Supplement_1): 799.

https://doi.org/10.1182/blood-2019-128416

Published: 2019

Journal Articles

Comparative Analysis of Alpha-Beta T-Cell and B-Cell Depleted (abTCD) HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT) Versus Abtcd Haplo-HSCT with T-Cell Add-Back of Rivogenlecleucel Cell [Donor T Cells Transduced with the Inducible Caspase 9 (iC9) Gene Safety Switch] in Children with High-Risk Acute Leukemia (AL) in Remission

Annalisa Ruggeri, MD, Pietro Merli, MD, Mattia Algeri, MD, Marco Zecca, Franca Fagioli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Arcangelo Prete, MD, Mauro Montanari, MD, Francesca Del Bufalo, MD, Luciana Vinti, MD, Daria Pagliara, MD PhD, Melissa Aldinger, PharmD, Kai Chan, Paul Woodard, Federica Galaverna, MD, Franco Locatelli, MD

Blood (2019) 134 (Supplement_1): 145.

https://doi.org/10.1182/blood-2019-125366

Published: 2019

Journal Articles

Results of a Multicentre, Randomized, Controlled Open-Label Study on the Use of Anti-T-Lymphocyte Globulin (ATLG) and Rituximab for Immunomodulation of Graft-Versus-Host Disease (GvHD) and Graft Failure (GF) in Patients with Non-Malignant Disorders

Mattia Algeri, MD, Stefania Galimberti, PhD, Maria Ester Bernardo, MD PhD, Attilio Rovelli, MD, Marco Zecca, MD, Giorgio La Nasa, MD, Sarah Marktel, MD, Pietro Merli, MD, Alice Bertaina, MD PhD, Daria Pagliara, MD PhD, Emilia Boccieri, MD, Francesca Del Bufalo, MD, Stefania Gaspari, MD, Giulia Capitoli, Maria Grazia Valsecchi, PhD, Franco Locatelli, MD PhD

Blood (2019) 134 (Supplement_1): 3280.

https://doi.org/10.1182/blood-2019-128925

Published: 2019

Journal Articles

Steroid-Refractory Acute Gvhd in Children: Retrospective Analysis of the AIEOP HSCT Registry

Marco Zecca, MD, Daria Pagliara, MD PhD, Franca Fagioli, MD, Attilio Rovelli, MD, Edoardo Lanino, MD, Arcangelo Prete, MD, Elisabetta Calore, MD, Stella Boghen, MD, Pietro Merli, MD, Francesca Compagno, MD, Mimmo Ripaldi, MD, Fulvio Porta, MD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 4578.

https://doi.org/10.1182/blood-2018-99-114862

Published: 2018

Journal Articles

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an HLA-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies

Joanne Shaw, PhD, Xiaoou Zhou, MD PhD, An Lu, Valentina Bertaina, Daria Pagliara, MD PhD, Melissa Aldinger, PharmD, David M. Spencer, PhD, Franco Locatelli, Aaron Foster, PhD

Blood (2018) 132 (Supplement 1): 4534.

https://doi.org/10.1182/blood-2018-99-119779

Published: 2018

Journal Articles

Administration of BPX-501 Cells Following Αβ- T and B-Cell-Depleted HLA-Haploidentical HSCT in Children with Fanconi Anemia

Swati Naik, MBBS, Susanne H.C. Baumeister, MD, Victor Aquino, MD, Annalisa Ruggeri, MD PhD, Daria Pagliara, MD PhD, Melissa Aldinger, PharmD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 4654.

https://doi.org/10.1182/blood-2018-99-119534

Published: 2018

Journal Articles

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

Pietro Merli, MD, Mattia Algeri, MD, Giuseppina Li Pira, PhD, Michela Falco, PhD, Daniela Pende, PhD, Valentina Bertaina, Daria Pagliara, MD PhD, Federica Galaverna, MD, Annalisa Ruggeri, MD PhD, Concetta Quintarelli, PhD, Lorenzo Moretta, MD PhD, Alice Bertaina, MD PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 2169.

https://doi.org/10.1182/blood-2018-99-117136

Published: 2018

Journal Articles

Administration of BPX-501 Following α-T and B-Cell Depleted Haplo-HSCT in Children with Transfusion-Dependent Thalassemia

Federica Galaverna, MD, Daria Pagliara, MD PhD, Deepa Manwani, MD, Rajni Agarwal, MD, Melissa Kuhn, PharmD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 166.

https://doi.org/10.1182/blood-2018-166

Published: 2018

Journal Articles

Clinical Outcome and Immune Recovery after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children with Hemoglobinopathies and Diamond-Blackfan Anemia Given α/β T-Cell Depleted HLA-Haploidentical Stem Cell Transplantation (HSCT)

Alice Bertaina, MDPhD, Pietro Merli, MD, Daria Pagliara, MD, Giuseppina Li Pira, PhD, Biagio De Angelis, PhD, Letizia Pomponia Brescia, MD, Luisa Strocchio, MD, Francesca Del Bufalo, MD, Mauro Montanari, MD, Barbarella Lucarelli, MD, Mattia Algeri, MD, Martha French, PhD, Annemarie Moseley, MDPhD, Franco Locatelli, MD

Blood (2016) 128 (22): 2286.

https://doi.org/10.1182/blood.V128.22.2286.2286

Published: 2016

Journal Articles

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Franco Locatelli, Prof, MD PhD, Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Mauro Montanari, MD, Daniela Pende, MD, Michela Falco, PhD, Daria Pagliara, MD, Maria Giuseppina Cefalo, MD, Alessandro Moretta, MD, Concetta Quintarelli, PhD, Brigitte Strahm, MD, Waseem Qasim, MBBS PhD, Mary Slatter, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD

Blood (2015) 126 (23): 1931.

https://doi.org/10.1182/blood.V126.23.1931.1931

Published: 2015

Journal Articles

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

Alice Bertaina, MDPhD, Barbarella Lucarelli, MD, Riccardo Masetti, MD, Pietro Merli, MD, Roberto Rondelli, MD, Giuseppina Li Pira, PhD, Marco Andreani, PhD, Lavinia Grapulin, MD, Daniela Pende, MD, Michela Falco, PhD, Maria Rita Pinto, MD, Valentina Bertaina, PhD, Maria Teresa Romano, MD, Stefano Ceccarelli, MD, Letizia Pomponia Brescia, MD, Daria Pagliara, MD, Alessandro Moretta, MD, Lorenzo Moretta, MD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 195.

https://doi.org/10.1182/blood.V126.23.195.195

Published: 2015

Journal Articles

Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Following Hematopoietic Stem Cell Transplantation or Chemotherapy--Results from the Italian Therapeutic Use Protocol

Franco Locatelli, MD PhD, Maura Faraci, MD, Simone Cesaro, MD, Daria Pagliara, MD, Franca Fagioli, MD, Marco Zecca, MD, Vian Amber, MBChB, MSc, PhD FRCPath, MFPM, Kamalika Banerjee, MS, Giorgia Finetto, Fabio Ciceri, MD

Blood (2015) 126 (23): 3107.

https://doi.org/10.1182/blood.V126.23.3107.3107

Published: 2015

Journal Articles

Recovery Of Gamma/Delta+ T Cells After Transplantation With Alpha-Beta+/CD19+ Lymphocyte Depleted Hematopoietic Stem Cells From HLA-Haploidentical Donors

Irma Airoldi, PhD, Ignazia Prigione, PhD, Alice Bertaina, MD, Claudia Cocco, PhD, Daria Pagliara, MD, Alessia Zorzoli, Dr., Sergio Rutella, MD, Rita M Pinto, MD, Vito Pistoia, MD, Riccardo Masetti, MD, Mariateresa Romano, MD, Francesca Di Florio, Dr, Francesca Del Bufalo, MD, Lorenzo Moretta, MD, Franco Locatelli

Blood (2013) 122 (21): 3245.

https://doi.org/10.1182/blood.V122.21.3245.3245

Published: 2013

Journal Articles

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Blood (2013) 122 (21): 157.

https://doi.org/10.1182/blood.V122.21.157.157

Published: 2013

Journal Articles

Indoleamine 2,3-Dioxygenase-1 (IDO1) Is Expressed by a Subset of Childhood Acute Myeloid Leukemias and Restrains IFN-γ Production by T Cells

Valentina Folgiero, BSc, Daniela Natale, BSc, Daria Pagliara, MD, Roberta Caruso, MD, Luciana Vinti, MD, Valentina Coletti, MD, Francesca Moretta, MD, Raimondo De Cristofaro, MD, Franco Locatelli, MD, PhD, Sergio Rutella, MD PhD

Blood (2012) 120 (21): 1430.

https://doi.org/10.1182/blood.V120.21.1430.1430

Published: 2012

Journal Articles

Negative Depletion of B Cells and T Cells Expressing the αβ Chain of the T-Cell Receptor (TCR) for Haploidentical Stem Cell Transplantation

Giuseppina Li Pira, BSc, Fabiola Landi, MD, Perla Filippini, BSc MSc, Paola Giustiniani, BSc, Alice Bertaina, MD, Daria Pagliara, MD, Rita M Pinto, MD, Katia Girardi, MD, Giovanna Del Principe, MD, Stefano Ceccarelli, MD, Franco Locatelli, MD, PhD, Sergio Rutella, MD, PhD

Blood (2012) 120 (21): 343.

https://doi.org/10.1182/blood.V120.21.343.343

Published: 2012

Journal Articles

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

Alice Bertaina, MD, Mariateresa Romano, MD, Sergio Rutella, MD PhD, Giuseppe Palumbo, MD, Daria Pagliara, MD, Stefano Ceccarelli, MD, Letizia P Brescia, MD, Giuseppina Li Pira, BSc, Francesca Cocca, MD, Maria Ester Bernardo, MD, Giuseppe M Milano, MD, Daniela Pende, PhD, Michela Falco, BSc, Lorenzo Moretta, MD, Franco Locatelli, MD, PhD

Blood (2012) 120 (21): 2018.

https://doi.org/10.1182/blood.V120.21.2018.2018

Published: 2012

Journal Articles

OUTCOME of Unrelated DONOR BONE MARROW TRANSPLANTATION for THALASSEMIA MAJOR PATIENTS

Franco Locatelli, MD, Roberto Littera, MD, Daria Pagliara, MD, Benedetta Contoli, PhD, Giovanna Giorgiani, MD, Maria Ester Bernardo, MD, Angela Mastronuzzi, MD, Eugenia Piras, MD, Maria Grazia Orofino, MD, Claudio Giardini, MD, Carlo Carcassi, MD, Giorgio La Nasa, MD

Blood (2011) 118 (21): 149.

https://doi.org/10.1182/blood.V118.21.149.149

Published: 2011

Journal Articles

IL15 Enhances Proliferation and Effector Function of Antigen-Specific Cytotoxic T Lymphocytes (CTLs) and Mitigates the Suppressive Action of Regulatory T Cells (Tregs).

Serena Kimi Perna, MD, Biagio De Angelis, PhD, Daria Pagliara, MD, Lan Zhan, Cliona M Rooney, PhD, Helen E. Heslop, MD, Malcolm K Brenner, MB, PhD, FRCP, FRCPath, Gianpietro Dotti, MD, Barbara Savoldo, MD, PhD

Blood (2009) 114 (22): 4088.

https://doi.org/10.1182/blood.V114.22.4088.4088

Published: 2009

NARROW

Outcome of Children with Different Non-Malignant Disorders Given Alphabeta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Long-Term Outcome of Children with Acute Leukemia (AL) Given Alphabeta T and B-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (TBdepl-haploHSCT)

Results of a Multicentre, Randomized, Controlled Open-Label Study on the Use of Anti-T-Lymphocyte Globulin (ATLG) and Rituximab for Immunomodulation of Graft-Versus-Host Disease (GvHD) and Graft Failure (GF) in Patients with Non-Malignant Disorders

Steroid-Refractory Acute Gvhd in Children: Retrospective Analysis of the AIEOP HSCT Registry

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an HLA-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies

Administration of BPX-501 Cells Following Αβ- T and B-Cell-Depleted HLA-Haploidentical HSCT in Children with Fanconi Anemia

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

Administration of BPX-501 Following α-T and B-Cell Depleted Haplo-HSCT in Children with Transfusion-Dependent Thalassemia

Clinical Outcome and Immune Recovery after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children with Hemoglobinopathies and Diamond-Blackfan Anemia Given α/β T-Cell Depleted HLA-Haploidentical Stem Cell Transplantation (HSCT)

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Following Hematopoietic Stem Cell Transplantation or Chemotherapy--Results from the Italian Therapeutic Use Protocol

Recovery Of Gamma/Delta+ T Cells After Transplantation With Alpha-Beta+/CD19+ Lymphocyte Depleted Hematopoietic Stem Cells From HLA-Haploidentical Donors

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Indoleamine 2,3-Dioxygenase-1 (IDO1) Is Expressed by a Subset of Childhood Acute Myeloid Leukemias and Restrains IFN-γ Production by T Cells

Negative Depletion of B Cells and T Cells Expressing the αβ Chain of the T-Cell Receptor (TCR) for Haploidentical Stem Cell Transplantation

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

OUTCOME of Unrelated DONOR BONE MARROW TRANSPLANTATION for THALASSEMIA MAJOR PATIENTS

IL15 Enhances Proliferation and Effector Function of Antigen-Specific Cytotoxic T Lymphocytes (CTLs) and Mitigates the Suppressive Action of Regulatory T Cells (Tregs).

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American Society of Hematology

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American Society of Hematology

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