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David Sinclair, PhD
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Journal Articles

SIRT1 Deacetylase Is Essential for Hematopoietic Stem Cell Activity Via Regulation of Foxo3.

Free
Pauline Rimmele, PhD, Carolina L. Bigarella, PhD, Valentina d'Escamard, MSc, Brigitte Izac, MSc, David Sinclair, PhD, Saghi Ghaffari, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2315.
https://doi.org/10.1182/blood.V120.21.2315.2315
Published: 2012
Journal Articles

Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice

Free
Sara Santos Franco, PhD student, Luigia De Falco, PhD, Saghi Ghaffari, MD, PhD, Carlo Brugnara, M.D., David Sinclair, PhD, Achille Iolascon, MD, PhD, Mohandas Narla, DSc, Mariarita Bertoldi, PhD, Christophe Lebouf, PhD, Anne Janin, MD, PhD, Angela Siciliano, Mrs, Pauline Rimmele, PhD, Maria Domenica Cappellini, MD, Shady Michan, PhD, Elisa Zoratti, PhD, Lucia De Franceschi, MD
Journal: Blood
Blood (2012) 120 (21): 3191.
https://doi.org/10.1182/blood.V120.21.3191.3191
Published: 2012
Journal Articles

Does Declining Mitochondrial NAD+ and Unscheduled Opening of Mitochondrial Transition Pore Promote Mammalian Aging?

Free
David Sinclair, PhD, Angela V. Hafner, Ana Gomes, Jing Liang, Yana Cen, Ian Lanza, Sree Nair, Anthony Sauve, Anthony Rozenzweig
Journal: Blood
Blood (2010) 116 (21): SCI-3.
https://doi.org/10.1182/blood.V116.21.SCI-3.SCI-3
Published: 2010
Journal Articles

Poly-Glutamine Induces Bax-Mediated Cell Death by Dissociating Ku70 from Bax through Ku70-Acetylation.

Free
Vivian Gama, MSc, Tomoyuki Yoshida, MSc, Haim Cohen, PhD, David Sinclair, PhD, Takanori Yokota, PhD, Clark Distelhorst, MD, Shigemi Matsuyama, PhD
Journal: Blood
Blood (2005) 106 (11): 4299.
https://doi.org/10.1182/blood.V106.11.4299.4299
Published: 2005